YRC Public Data Repository - Protein Structure Prediction

Protein:	HTA1
Organism:	Saccharomyces cerevisiae
Length:	132 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HTA1.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-44	[3..131]	[9..137]
H2A2B_MOUSE - Histone H2A type 2-B OS=Mus musculus GN=Hist2h2ab PE=1 SV=3	1.0E-44	[3..131]	[2..130]
H2A1_XENLA - Histone H2A type 1 OS=Xenopus laevis PE=1 SV=2	1.0E-44	[3..131]	[2..130]
gi\|57110421 - gi\|57110421\|ref\|XP_545390.1\| PREDICTED: similar to Histone H2A.l (H2A/l) isoform 1 [Canis familiaris... CCDS4585.1_1 - null tr\|M3WYW4\|M3WYW4... - Histone H2A OS=Felis catus GN=LOC101092025 PE=3 SV=1 gi\|76651036, gi\|... - gi\|76651036\|ref\|XP_874740.1\| PREDICTED: similar to Histone H2A.l (H2A/l) isoform 2 [Bos taurus], gi\|... gi\|60821950, gi\|... - gi\|60821988\|gb\|AAX36593.1\| histone 1 H2ac [synthetic construct], gi\|60821950\|gb\|AAX36592.1\| histone ... HIST1H2AC - histone cluster 1, H2ac gi\|109069890 - gi\|109069890\|ref\|XP_001086273.1\| PREDICTED: similar to Histone H2A type 1-C [Macaca mulatta] gi\|149731868 - gi\|149731868\|ref\|XP_001497361.1\| PREDICTED: similar to Histone H2A type 1-C (H2A/l) [Equus caballus] ENSOCUP000000075... - pep:novel chromosome:oryCun2:12:10943921:10944313:-1 gene:ENSOCUG00000024878 transcript:ENSOCUT00000... gi\|55625972 - gi\|55625972\|ref\|XP_518286.1\| PREDICTED: similar to histone H2A [Pan troglodytes] gi\|194039784, gi... - gi\|194039834\|ref\|XP_001928159.1\| PREDICTED: similar to Histone H2A type 1-C (H2A/l) [Sus scrofa], gi... H2A1C_RAT - Histone H2A type 1-C OS=Rattus norvegicus PE=1 SV=2	1.0E-44	[3..131]	[2..130]
H2A_ONCMY - Histone H2A OS=Oncorhynchus mykiss PE=1 SV=2	2.0E-44	[3..129]	[2..128]
gi\|14549635 - gi\|14549635\|gb\|AAK66965.1\|AF255739_1 replication-dependent histone H2A [Bufo bufo gagarizans]	2.0E-44	[3..131]	[2..130]

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Predicted Domain #1

Region A:
Residues: [1-59]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGGKGGKAG SAAKASQSRS AKAGLTFPVG RVHRLLRRGN YAQRIGSGAP VYLTAVLEY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	579.383689
Match:	1id3C_
Description:	Histone H2A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.581886805340955	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [60-132]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAAEILELAG NAARDNKKTR IIPRHLQLAI RNDDELNKLL GNVTIAQGGV LPNIHQNLLP  60
   61 KKSAKATKAS QEL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	579.383689
Match:	1id3C_
Description:	Histone H2A
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: