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View Structure Prediction Details

Protein: SPR28
Organism: Saccharomyces cerevisiae
Length: 423 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPR28.

Description E-value Query
Range
Subject
Range
gi|2978511 - gi|2978511|gb|AAC39780.1| septin [Homo sapiens]
0.0 [10..400] [71..416]
SEPT4_MOUSE - Septin-4 OS=Mus musculus GN=Sept4 PE=1 SV=1
0.0 [10..400] [123..476]
gi|28922725, gi|... - gi|32404966|ref|XP_323096.1| probable cell division control protein CDC12 [MIPS] [Neurospora crassa]...
gi|85101640 - gi|85101640|ref|XP_961184.1| cell division control protein 12 [Neurospora crassa OR74A]
0.0 [1..423] [1..379]
gi|220955920, gi... - gi|220955920|gb|ACL90503.1| pnut-PA [synthetic construct], gi|220946224|gb|ACL85655.1| pnut-PA [synt...
pnut-PA, pnut-PB - The gene peanut is referred to in FlyBase by the symbol Dmel\pnut (CG8705, FBgn0013726). It is a pro...
0.0 [2..418] [115..484]
SEPT5_MACFA - Septin-5 OS=Macaca fascicularis GN=Sept5 PE=2 SV=1
0.0 [10..400] [32..377]

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Predicted Domain #1
Region A:
Residues: [1-246]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFPMKDHSAL EQHTLSRDEL RRRKGYKKGL QLSILLLGEK GSGKSTFLNN LCGQDISLSD  60
   61 GDYDDDDDKV TNNVTPENGN AIEDIDPGYK TAHLSPGLKL VTRRVYLNDE LGVPITLDII 120
  121 LFPGCGDNVD NSQSSVVIKN YLDQQFANVL KEEVRIKRNT KETDGRPHVC LYFLKSTPRG 180
  181 VKKFDIELMK TICDKVNLIP IIPKADGLTE TELNLHKDIV RQEISQNNIR VFDFKSDTLG 240
  241 ETLALY

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.79
Match: 1egaA
Description: GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [247-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMDIDSSSAK SKYDNDTKIK EISPFAIVCS KTFNKNSENR VEHIRTYEWG SLVVEDQNTS  60
   61 DFIYLKAILL GSHLQELKDV TNNVLYENYR AKVLTEKKNN YDIPN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.79
Match: 1egaA
Description: GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [352-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSYIDETSRG SVSNVSTRRN SASRTLGNPD TNDENAYQIH KEIDEKNRII EDYQRKIDLL  60
   61 EKMLAAPHQN KV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.406 0.016 structural constituent of cytoskeleton a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.401 0.013 structural constituent of cytoskeleton a.144.1 PABC (PABP) domain
View Download 0.432 0.009 structural constituent of cytoskeleton a.60.9 lambda integrase-like, N-terminal domain
View Download 0.477 0.003 structural constituent of cytoskeleton a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.380 0.002 structural constituent of cytoskeleton a.46.1 Methionine synthase domain
View Download 0.295 N/A N/A a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.258 N/A N/A a.156.1 S13-like H2TH domain
View Download 0.255 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.254 N/A N/A a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.251 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.248 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.246 N/A N/A a.64.1 Saposin
View Download 0.238 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.219 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.212 N/A N/A a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.211 N/A N/A a.5.2 UBA-like
View Download 0.206 N/A N/A a.39.1 EF-hand
View Download 0.200 N/A N/A a.3.1 Cytochrome c


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle