| Protein: | UPC2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 913 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UPC2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..913] | [1..913] |
|
|
6.0E-63 | [605..760] | [102..244] |
|
|
1.0E-53 | [8..268] | [7..275] |
|
|
2.0E-50 | [8..268] | [7..276] |
|
|
4.0E-50 | [38..331] | [11..334] |
|
Region A: Residues: [1-166] |
1 11 21 31 41 51
| | | | | |
1 MSEVGIQNHK KAVTKPRRRE KVIELIEVDG KKVSTTSTGK RKFHNKSKNG CDNCKRRRVK 60
61 CDEGKPACRK CTNMKLECQY TPIHLRKGRG ATVVKYVTRK ADGSVESDSS VDLPPTIKKE 120
121 QTPFNDIQSA VKASGSSNDS FPSSASTTKS ESEEKSSAPI EDKNNM
|
| Detection Method: |  |
| Confidence: | 46.502279 |
| Match: | 1pyiA_ |
| Description: | PPR1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 0.226078362275538 | bayes_pls_golite062009 |
|
Region A: Residues: [167-645] |
1 11 21 31 41 51
| | | | | |
1 TPLSMGLQGT INKKDMMNNF FSQNGTIGFG SPERLNSGID GLLLPPLPSG NMGAFQLQQQ 60
61 QQVQQQSQPQ TQAQQASGTP NERYGSFDLA GSPALQSTGM SLSNSLSGML LCNRIPSGQN 120
121 YTQQQLQYQL HQQLQLQQHQ QVQLQQYQQL RQEQHQQVQQ QQQEQLQQYQ QHFLQQQQQV 180
181 LLQQEQQPND EEGGVQEENS KKVKEGPLQS QTSETTLNSD AATLQADALS QLSKMGLSLK 240
241 SLSTFPTAGI GGVSYDFQEL LGIKFPINNG NSRATKASNA EEALANMQEH HERAAASVKE 300
301 NDGQLSDTKS PAPSNNAQGG SASIMEPQAA DAVSTMAPIS MIERNMNRNS NISPSTPSAV 360
361 LNDRQEMQDS ISSLGNLTKA ALENNEPTIS LQTSQTENED DASRQDMTSK INNEADRSSV 420
421 SAGTSNIAKL LDLSTKGNLN LIDMKLFHHY CTKVWPTITA AKVSGPEIWR DYIPELAFD
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [646-794] |
1 11 21 31 41 51
| | | | | |
1 YPFLMHALLA FSATHLSRTE TGLEQYVSSH RLDALRLLRE AVLEISENNT DALVASALIL 60
61 IMDSLANASG NGTVGNQSLN SMSPSAWIFH VKGAATILTA VWPLSERSKF HNIISVDLSD 120
121 LGDVINPDVG TITELVCFDE SIADLYPVG
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.723 | 0.231 | sterol biosynthetic process | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.514 | 0.047 | sterol biosynthetic process | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.648 | 0.042 | sterol biosynthetic process | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.545 | 0.014 | sterol biosynthetic process | a.24.4 | Hemerythrin |
| View | Download | 0.557 | 0.007 | sterol biosynthetic process | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.453 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.446 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.442 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.441 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.430 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.425 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.389 | N/A | N/A | a.5.4 | Elongation factor TFIIS domain 2 |
| View | Download | 0.385 | N/A | N/A | a.185.1 | Gametocyte protein Pfg27 |
| View | Download | 0.376 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.369 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.355 | N/A | N/A | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.349 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.329 | N/A | N/A | a.72.1 | Functional domain of the splicing factor Prp18 |
| View | Download | 0.326 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.321 | N/A | N/A | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.317 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.316 | N/A | N/A | a.126.1 | Serum albumin-like |
| View | Download | 0.294 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.280 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.271 | N/A | N/A | d.92.1 | Metalloproteases ("zincins"), catalytic domain |
| View | Download | 0.263 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.258 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.258 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.253 | N/A | N/A | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.250 | N/A | N/A | a.168.1 | GEF domain of SopE toxin |
| View | Download | 0.239 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.239 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.239 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.233 | N/A | N/A | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.233 | N/A | N/A | d.110.2 | GAF domain-like |
| View | Download | 0.232 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.226 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.225 | N/A | N/A | a.63.1 | Apolipophorin-III |
| View | Download | 0.219 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.219 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.215 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.213 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.213 | N/A | N/A | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.210 | N/A | N/A | a.79.1 | Antitermination factor NusB |
| View | Download | 0.207 | N/A | N/A | a.118.16 | Testis/brain RNA-binding protein (TB-RBP) |
| View | Download | 0.207 | N/A | N/A | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.207 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.202 | N/A | N/A | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
|
Region A: Residues: [795-913] |
1 11 21 31 41 51
| | | | | |
1 LDSPYLITLA YLDKLHREKN QGDFILRVFT FPALLDKTFL ALLMTGDLGA MRIMRSYYKL 60
61 LRGFATEVKD KVWFLEGVTQ VLPQDVDEYS GGGGMHMMLD FLGGGLPSMT TTNFSDFSL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.932 | 0.078 | sterol biosynthetic process | a.118.8 | TPR-like |
| View | Download | 0.863 | 0.078 | sterol biosynthetic process | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.766 | 0.078 | sterol biosynthetic process | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.757 | 0.078 | sterol biosynthetic process | a.24.4 | Hemerythrin |
| View | Download | 0.722 | 0.078 | sterol biosynthetic process | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.723 | 0.078 | sterol biosynthetic process | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.648 | 0.078 | sterol biosynthetic process | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.648 | 0.078 | sterol biosynthetic process | a.118.16 | Testis/brain RNA-binding protein (TB-RBP) |
| View | Download | 0.623 | 0.078 | sterol biosynthetic process | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.591 | 0.078 | sterol biosynthetic process | b.88.1 | Mss4-like |
| View | Download | 0.572 | 0.078 | sterol biosynthetic process | a.7.7 | BAG domain |
| View | Download | 0.567 | 0.078 | sterol biosynthetic process | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.557 | 0.078 | sterol biosynthetic process | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.545 | 0.078 | sterol biosynthetic process | a.24.4 | Hemerythrin |
| View | Download | 0.523 | 0.078 | sterol biosynthetic process | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.519 | 0.078 | sterol biosynthetic process | a.7.1 | Spectrin repeat |
| View | Download | 0.517 | 0.078 | sterol biosynthetic process | a.24.3 | Cytochromes |
| View | Download | 0.514 | 0.078 | sterol biosynthetic process | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.501 | 0.078 | sterol biosynthetic process | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.484 | 0.078 | sterol biosynthetic process | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.483 | 0.078 | sterol biosynthetic process | d.91.1 | N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 |
| View | Download | 0.463 | 0.078 | sterol biosynthetic process | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.456 | 0.078 | sterol biosynthetic process | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.451 | 0.078 | sterol biosynthetic process | a.47.2 | t-snare proteins |
| View | Download | 0.446 | 0.078 | sterol biosynthetic process | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.422 | 0.078 | sterol biosynthetic process | a.47.2 | t-snare proteins |
| View | Download | 0.418 | 0.078 | sterol biosynthetic process | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.417 | 0.078 | sterol biosynthetic process | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.411 | 0.078 | sterol biosynthetic process | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.408 | 0.078 | sterol biosynthetic process | a.7.7 | BAG domain |
| View | Download | 0.403 | 0.078 | sterol biosynthetic process | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.403 | 0.078 | sterol biosynthetic process | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.400 | 0.078 | sterol biosynthetic process | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.391 | 0.078 | sterol biosynthetic process | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.389 | 0.078 | sterol biosynthetic process | a.7.8 | GAT domain |
| View | Download | 0.376 | 0.078 | sterol biosynthetic process | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.375 | 0.078 | sterol biosynthetic process | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.365 | 0.078 | sterol biosynthetic process | a.118.1 | ARM repeat |
| View | Download | 0.359 | 0.078 | sterol biosynthetic process | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.347 | 0.078 | sterol biosynthetic process | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.340 | 0.078 | sterol biosynthetic process | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.336 | 0.078 | sterol biosynthetic process | c.120.1 | PIN domain-like |
| View | Download | 0.335 | 0.078 | sterol biosynthetic process | a.47.2 | t-snare proteins |
| View | Download | 0.328 | 0.078 | sterol biosynthetic process | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.327 | 0.078 | sterol biosynthetic process | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.326 | 0.078 | sterol biosynthetic process | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.322 | 0.078 | sterol biosynthetic process | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.320 | 0.078 | sterol biosynthetic process | a.26.1 | 4-helical cytokines |
| View | Download | 0.314 | 0.078 | sterol biosynthetic process | a.74.1 | Cyclin-like |
| View | Download | 0.296 | 0.078 | sterol biosynthetic process | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.291 | 0.078 | sterol biosynthetic process | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.285 | 0.078 | sterol biosynthetic process | a.5.4 | Elongation factor TFIIS domain 2 |
| View | Download | 0.281 | 0.078 | sterol biosynthetic process | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.269 | 0.078 | sterol biosynthetic process | a.118.7 | 14-3-3 protein |
| View | Download | 0.266 | 0.078 | sterol biosynthetic process | a.7.1 | Spectrin repeat |
| View | Download | 0.265 | 0.078 | sterol biosynthetic process | a.118.12 | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain |
| View | Download | 0.264 | 0.078 | sterol biosynthetic process | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.262 | 0.078 | sterol biosynthetic process | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.252 | 0.078 | sterol biosynthetic process | d.81.1 | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |
| View | Download | 0.247 | 0.078 | sterol biosynthetic process | a.118.9 | ENTH/VHS domain |
| View | Download | 0.242 | 0.078 | sterol biosynthetic process | f.32.1 | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.240 | 0.078 | sterol biosynthetic process | a.2.3 | Chaperone J-domain |
| View | Download | 0.240 | 0.078 | sterol biosynthetic process | d.162.1 | LDH C-terminal domain-like |
| View | Download | 0.231 | 0.078 | sterol biosynthetic process | a.25.1 | Ferritin-like |
| View | Download | 0.231 | 0.078 | sterol biosynthetic process | a.2.7 | tRNA-binding arm |
| View | Download | 0.227 | 0.078 | sterol biosynthetic process | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.224 | 0.078 | sterol biosynthetic process | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.224 | 0.078 | sterol biosynthetic process | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.223 | 0.078 | sterol biosynthetic process | a.29.2 | Bromodomain |
| View | Download | 0.223 | 0.078 | sterol biosynthetic process | a.118.9 | ENTH/VHS domain |
| View | Download | 0.222 | 0.078 | sterol biosynthetic process | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.220 | 0.078 | sterol biosynthetic process | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.220 | 0.078 | sterol biosynthetic process | a.26.1 | 4-helical cytokines |
| View | Download | 0.218 | 0.078 | sterol biosynthetic process | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.214 | 0.078 | sterol biosynthetic process | a.26.1 | 4-helical cytokines |
| View | Download | 0.211 | 0.078 | sterol biosynthetic process | a.79.1 | Antitermination factor NusB |
| View | Download | 0.204 | 0.078 | sterol biosynthetic process | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.201 | 0.078 | sterol biosynthetic process | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.201 | 0.078 | sterol biosynthetic process | a.25.1 | Ferritin-like |
|
Region A: Residues: [757-913] |
1 11 21 31 41 51
| | | | | |
1 NIISVDLSDL GDVINPDVGT ITELVCFDES IADLYPVGLD SPYLITLAYL DKLHREKNQG 60
61 DFILRVFTFP ALLDKTFLAL LMTGDLGAMR IMRSYYKLLR GFATEVKDKV WFLEGVTQVL 120
121 PQDVDEYSGG GGMHMMLDFL GGGLPSMTTT NFSDFSL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.932 | a.118.8 | TPR-like |
| View | Download | 0.863 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.766 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.757 | a.24.4 | Hemerythrin |
| View | Download | 0.722 | a.7.6 | Ribosomal protein S20 |
