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View Structure Prediction Details

Protein: VPS64
Organism: Saccharomyces cerevisiae
Length: 604 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS64.

Description E-value Query
Range		 Subject
Range
gi|190404846 - gi|190404846|gb|EDV08113.1| vacuolar protein sorting protein 64 [Saccharomyces cerevisiae RM11-1a]
VPS64 - Protein required for cytoplasm to vacuole targeting of proteins; forms a complex with Far3p and Far7...
VPS64_YEAST - Vacuolar protein sorting-associated protein 64 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
 7.0E-79 [1..604] [1..604]
gck-4 - serine\/threonine kinase status:Partially_confirmed UniProt:O17566 protein_id:CAB03829.1
 4.0E-36 [7..576] [646..1207]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
 1.0E-29 [132..603] [929..1410]
gi|179508, gi|10... - sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta), gi|4557773|ref|NP...
 2.0E-28 [110..604] [1376..1884]
MYH7_MOUSE - Myosin-7 OS=Mus musculus GN=Myh7 PE=1 SV=1
 2.0E-28 [110..604] [1376..1884]

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Predicted Domain #1
Region A:
Residues: [1-152] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVELEKRRRP PPQLQHSPYV RDQSNSQGMT KTPETSPPKR PMGRARSNSR SSGSRSNVDI  60
   61 DQYTIPPGLD LLPTASSPPS VHQVSQQQQL SPILANKIRS PFENQSQDQN DNSIDPTPAG 120
  121 QVTIPVEAVS PPALDELSKF QNGSTETLFR TG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [153-219] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPRKKHTHII ILKSLNATFE TKFLVVPFKP DGLKLGRPVT NSVNKNNSGS KRDLFSQQVR  60
   61 PDNGNFD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.921 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.824 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.798 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.795 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.787 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.773 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.743 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.739 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.698 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.687 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.667 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.654 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.614 0.288 protein targeting to vacuole d.15.2 CAD & PB1 domains
View Download 0.608 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.549 0.288 protein targeting to vacuole d.15.7 Immunoglobulin-binding domains
View Download 0.479 0.288 protein targeting to vacuole d.15.1 Ubiquitin-like
View Download 0.433 0.288 protein targeting to vacuole b.2.2 Carbohydrate-binding domain
View Download 0.382 0.288 protein targeting to vacuole b.55.1 PH domain-like
View Download 0.378 0.288 protein targeting to vacuole d.15.1 Ubiquitin-like
View Download 0.378 0.288 protein targeting to vacuole d.15.2 CAD & PB1 domains
View Download 0.368 0.288 protein targeting to vacuole b.44.1 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
View Download 0.364 0.288 protein targeting to vacuole b.71.1 Glycosyl hydrolase domain
View Download 0.356 0.288 protein targeting to vacuole d.27.1 Ribosomal protein S16
View Download 0.355 0.288 protein targeting to vacuole d.15.2 CAD & PB1 domains
View Download 0.350 0.288 protein targeting to vacuole b.44.1 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
View Download 0.349 0.288 protein targeting to vacuole b.1.18 E set domains
View Download 0.326 0.288 protein targeting to vacuole d.15.2 CAD & PB1 domains
View Download 0.326 0.288 protein targeting to vacuole b.44.1 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
View Download 0.318 0.288 protein targeting to vacuole b.4.1 HSP40/DnaJ peptide-binding domain
View Download 0.313 0.288 protein targeting to vacuole b.61.2 Metalloprotease inhibitor
View Download 0.311 0.288 protein targeting to vacuole d.19.1 MHC antigen-recognition domain
View Download 0.302 0.288 protein targeting to vacuole d.15.1 Ubiquitin-like
View Download 0.295 0.288 protein targeting to vacuole b.1.5 Transglutaminase, two C-terminal domains
View Download 0.287 0.288 protein targeting to vacuole b.1.1 Immunoglobulin
View Download 0.279 0.288 protein targeting to vacuole b.1.1 Immunoglobulin
View Download 0.274 0.288 protein targeting to vacuole d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.266 0.288 protein targeting to vacuole d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.238 0.288 protein targeting to vacuole b.1.2 Fibronectin type III
View Download 0.231 0.288 protein targeting to vacuole b.43.3 Translation proteins
View Download 0.215 0.288 protein targeting to vacuole d.129.1 TATA-box binding protein-like
View Download 0.211 0.288 protein targeting to vacuole d.129.1 TATA-box binding protein-like
View Download 0.206 0.288 protein targeting to vacuole d.129.1 TATA-box binding protein-like
View Download 0.205 0.288 protein targeting to vacuole d.15.1 Ubiquitin-like

Predicted Domain #3
Region A:
Residues: [220-604] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRVLSRNHAC LSCDPTSGKI YIRDLKSSNG TFVNGVKIRQ NDVELKVGDT VDLGTDIDSK  60
   61 FEHRKISAYV EEISVIPLMN TVSDPTNLVM KKQDHTNKNN GNSTNINGIK IDRGHHNQHI 120
  121 PIRSHLKENY TEAGVTSATT AQRAAFEAAM FGDINNSELD DDILGPETEV LSGIFINNSA 180
  181 GTSINLINMI KTLTTELSLE KQELEKLHSM QNFMQNYTIN LDFINKHMID MNEKHLLKLS 240
  241 TALQKTLSEN NDALLKESED QLKEIKQQNN KVKSACSLKE KQNHEKLQEL ESELRELNLQ 300
  301 IEEERGKNLV LTQSNFNGGI NNDNNAKVKQ NDSREEKKDT EDTLISTEEL GVVEGKRTRV 360
  361 SKGMLFGVVA ISFGLVATAV KQLPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle