YRC Public Data Repository - Protein Structure Prediction

Protein:	YDR186C
Organism:	Saccharomyces cerevisiae
Length:	877 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR186C.

Description	E-value	Query Range	Subject Range
gi\|44985743 - gi\|44985743\|gb\|AAS54367.1\| AGL124Cp [Ashbya gossypii ATCC 10895] gi\|45200973, gi\|... - gi\|45200973\|ref\|NP_986543.1\| AGL124Cp [Ashbya gossypii ATCC 10895], gi\|44985743\|gb\|AAS54367.1\| AGL12...	278.0	[0..23]	[344..11]
gi\|49643009, gi\|... - gi\|50307763\|ref\|XP_453875.1\| unnamed protein product [Kluyveromyces lactis], gi\|49643009\|emb\|CAH0097... gi\|49643009 - gi\|49643009\|emb\|CAH00971.1\| KLLA0D18392p [Kluyveromyces lactis]	262.0	[0..9]	[350..3]
gi\|50287577, gi\|... - gi\|50287577\|ref\|XP_446218.1\| unnamed protein product [Candida glabrata], gi\|49525525\|emb\|CAG59142.1\|... gi\|49525525 - gi\|49525525\|emb\|CAG59142.1\| unnamed protein product [Candida glabrata]	205.0	[0..25]	[332..6]
gi\|57228946, gi\|... - gi\|58271062\|ref\|XP_572687.1\| ubiquitin-protein ligase [Cryptococcus neoformans var. neoformans JEC21...	61.0	[0..268]	[563..2032]
gi\|50256705, gi\|... - gi\|50256705\|gb\|EAL19428.1\| hypothetical protein CNBH1200 [Cryptococcus neoformans var. neoformans B-...	61.0	[0..268]	[563..2118]

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Predicted Domain #1

Region A:
Residues: [1-77]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTVGTDAAA ASINERRFAQ STSPKVSVKS QDSLFLITYS NMQQTVVQAS LADRYPSLKK  60
   61 LNILLYIDIP TIDYYND

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [78-414]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EMTHNKLSRL NKRFKLHRLR NSIAQSFSNT STAEDNDKFW EELKSLISSR STPENKFDLN  60
   61 VLVSSSGSLR YVETIRFLVE KLFNSFKDLY VQKKLNLCFQ INVSPTSLKW FSTFLNAELL 120
  121 NLKIINWQNI GSFTKTIQNS KSLPFKEYYT KLNEKFTGSN QSNGSMQDQT VLDSIVIVTN 180
  181 STGVKALLTL LSDHPLTSLI SQESIKALHE YSDAVNEDKG DDQSNTSLKR NSSSLLNFQN 240
  241 SVLTSNKDKS VRIRSLSINR KSNRAHMFKT NESITTIPST SINNLIGQES NLRKQPSGTA 300
  301 LHLQSHLHPH SRSQSYSSSN MSRSPSPFPY GKTPSND

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	8.17
Match:
Description:	No description for 1l9uD was found.

Predicted Domain #3

Region A:
Residues: [415-489]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELVYDELNNQ INEVQDRAKN EEIVLYNNNN YDDYTKERGE QEQDRTSYAD EYGFNYDDEE  60
   61 GGNEDNYDDD EDDDD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [490-877]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDDDDESDD EGLSFYAPSI LSRSGSSTDV LSSGIDSMAK NSKETRGRFR SLSLMDPALQ  60
   61 KPFNQKFPNS QQPDSAGASS PKRSTSSNHF TNVYVHDGDF DGTDTINNKK NLSSATLIKR 120
  121 KSLMNRNLAP SISNGLIPPE FISRISTPST SASSSNSSLN DMSTVSNAFS KLLNDTSKKQ 180
  181 KFLNSPIPQH TQQASPLLMR NNSNSNLLFE KNLINKSFEE LRRQPSVNLF STLMNGNMEK 240
  241 NGLALNFKSR TPTDALMANS IKNSNNSSHR LLNLEEEDQI MSGSLPKERE DDNDSTNSTI 300
  301 VPNHPDNDNY NDNDNDNNTG INSNNFNLNL YDDNDSAGFT DVTTEGVKYS NSNSTVTKPV 360
  361 YKKAVTLDLY GEDDMDNMGG WVLGGNAR

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	7.58
Match:
Description:	No description for 1iu4A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits