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View Structure Prediction Details

Protein: HSP42
Organism: Saccharomyces cerevisiae
Length: 375 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSP42.

Description E-value Query
Range		 Subject
Range
HSP42 - Small heat shock protein (sHSP) with chaperone activity; forms barrel-shaped oligomers that suppress...
gi|207346637 - gi|207346637|gb|EDZ73077.1| YDR171Wp-like protein [Saccharomyces cerevisiae AWRI1631]
HSP42_YEAST - Heat shock protein 42 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HSP42 PE=1 SV=1
gi|190404874 - gi|190404874|gb|EDV08141.1| heat shock protein 42 [Saccharomyces cerevisiae RM11-1a]
 0.0 [1..375] [1..375]
HS22C_PETHY - Small heat shock protein, chloroplastic OS=Petunia hybrida GN=HSP22 PE=2 SV=1
 2.0E-46 [138..345] [42..234]
gi|4028567, gi|2... - gi|4028567|gb|AAC96314.1| heat shock protein HSP26 [Triticum aestivum], gi|220675835|emb|CAM12753.1|...
 2.0E-45 [144..345] [36..231]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 5.0E-45 [138..354] [39..240]
gi|8671873 - gi|8671873|gb|AAF78436.1|AC018748_15 Contains similarity to 17.6 KD class I heat shock protein from ...
 8.0E-45 [193..356] [245..402]
HS21C_SOLLC - Small heat shock protein, chloroplastic OS=Solanum lycopersicum GN=HSP21 PE=2 SV=1
 2.0E-44 [141..354] [38..235]
HSP13_SOYBN - 17.5 kDa class I heat shock protein OS=Glycine max GN=HSP17.5-M PE=3 SV=1
 8.0E-44 [195..356] [1..152]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 1.0E-43 [195..356] [1..153]

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Predicted Domain #1
Region A:
Residues: [1-188] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFYQPSLSL YDVLNALSNQ TGQRGQQGYP RQPQRPQRYH PHYGQVHVGG HHPRHHPLYS  60
   61 RYNGVPNTYY YQFPGQAYYY SPEYGYDDED GEEEDQDEDM VGDSGTTRQE DGGEDSNSRR 120
  121 YPSYYHCNTA RNNRTNQQAN SLNDLLTALI GVPPYEGTEP EIEANTEQEG EKGEEKDKKD 180
  181 KSEAPKEE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [189-375] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGETNKEKPL NQLEESSRPP LAKKSSSFAH LQAPSPIPDP LQVSKPETRM DLPFSPEVNV  60
   61 YDTEDTYVVV LALPGANSRA FHIDYHPSSH EMLIKGKIED RVGIDEKFLK ITELKYGAFE 120
  121 RTVKFPVLPR IKDEEIKATY NNGLLQIKVP KIVNDTEKPK PKKRIAIEEI PDEELEFEEN 180
  181 PNPTVEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.30103
Match: 1gmeA_
Description: Small heat shock protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
unfolded protein binding 2.66693334592032 bayes_pls_golite062009
binding 1.39874024053677 bayes_pls_golite062009
protein binding 0.950651976327201 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle