| Protein: | VBA4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 768 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VBA4.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..768] | [1..768] |
|
|
2.0E-99 | [144..767] | [32..634] |
|
|
3.0E-99 | [227..762] | [12..522] |
|
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1.0E-95 | [234..764] | [29..543] |
|
|
3.0E-93 | [164..763] | [14..592] |
|
|
7.0E-92 | [228..764] | [1..509] |
|
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2.0E-91 | [205..754] | [2..550] |
|
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3.0E-91 | [242..756] | [6..500] |
|
|
4.0E-91 | [242..756] | [6..500] |
|
Region A: Residues: [1-74] |
1 11 21 31 41 51
| | | | | |
1 MGKKDRQRKK LREFAKLKNR QRNLRKSVQT LKNEVQREAK VPRTSNQIAL GNDKIEEINE 60
61 NSPLLSAPSK QEEV
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.646 | a.4.1 | Homeodomain-like |
| View | Download | 0.634 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.499 | d.95.1 | Glucose permease domain IIB |
| View | Download | 0.482 | a.17.1 | p8-MTCP1 |
| View | Download | 0.584 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.472 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.463 | a.28.1 | ACP-like |
| View | Download | 0.447 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.424 | a.4.1 | Homeodomain-like |
| View | Download | 0.423 | a.28.1 | ACP-like |
| View | Download | 0.420 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.417 | g.53.1 | TAZ domain |
| View | Download | 0.414 | d.95.2 | Homing endonucleases |
| View | Download | 0.414 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.405 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.402 | a.4.1 | Homeodomain-like |
| View | Download | 0.396 | a.47.2 | t-snare proteins |
| View | Download | 0.390 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.389 | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.367 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.366 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.358 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.356 | a.39.1 | EF-hand |
| View | Download | 0.355 | a.28.2 | Colicin E immunity proteins |
| View | Download | 0.342 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.342 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.341 | a.41.1 | Domain of poly(ADP-ribose) polymerase |
| View | Download | 0.339 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.337 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.336 | a.28.1 | ACP-like |
| View | Download | 0.331 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.330 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.327 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.321 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.318 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.315 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.303 | a.28.1 | ACP-like |
| View | Download | 0.299 | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.295 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.293 | a.17.1 | p8-MTCP1 |
| View | Download | 0.292 | a.2.3 | Chaperone J-domain |
| View | Download | 0.284 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.282 | a.28.1 | ACP-like |
| View | Download | 0.280 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.278 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.274 | a.41.1 | Domain of poly(ADP-ribose) polymerase |
| View | Download | 0.273 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.269 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.268 | a.17.1 | p8-MTCP1 |
| View | Download | 0.267 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.262 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.262 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.256 | a.41.1 | Domain of poly(ADP-ribose) polymerase |
| View | Download | 0.255 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.248 | a.64.1 | Saposin |
| View | Download | 0.243 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.241 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.239 | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.232 | a.21.1 | HMG-box |
| View | Download | 0.229 | a.135.1 | Tetraspanin |
| View | Download | 0.227 | a.153.1 | Nuclear receptor coactivator interlocking domain |
| View | Download | 0.226 | g.53.1 | TAZ domain |
| View | Download | 0.225 | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.224 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.218 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.216 | a.7.7 | BAG domain |
| View | Download | 0.214 | a.157.1 | Skp1 dimerisation domain-like |
| View | Download | 0.212 | a.118.14 | FliG |
| View | Download | 0.211 | a.47.2 | t-snare proteins |
| View | Download | 0.208 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.207 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.207 | a.4.1 | Homeodomain-like |
| View | Download | 0.206 | a.28.2 | Colicin E immunity proteins |
| View | Download | 0.205 | a.64.1 | Saposin |
| View | Download | 0.202 | d.95.2 | Homing endonucleases |
| View | Download | 0.202 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.202 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.201 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
|
Region A: Residues: [75-244] |
1 11 21 31 41 51
| | | | | |
1 SIPKAVDIDT IDAQPLHEGP KIDDSPQDEV NSIKGKPADK ANEDDLKPPS QHEACGNSAL 60
61 QSSITDFSDR SVSPLQSITS CNTPMSEHEL PVSSSNSFER ADDMPVVQAD NQTSSSKSLH 120
121 IVAPSPEVPV SGDEITSYGY GSIPQSIGDV ENGLNPPYVE NTSSDELVHD
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| transporter activity | 1.47137690164233 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.05831640191854 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.04845870423152 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.01835310550526 | bayes_pls_golite062009 |
| binding | 0.0875556388382674 | bayes_pls_golite062009 |
|
Region A: Residues: [245-427] |
1 11 21 31 41 51
| | | | | |
1 LTRRRIFSSC MCTYLFFIAM DSSIILVIAS KIASEFHELW RLSLVISAYL LSNAIGQLVF 60
61 LKLSLISSVK LLLCIAQFSF ILGGYLSWSS AHFWTFIFAR CVTGFGGGSL IALKSTIMNR 120
121 FSQKNDSRYS LSASMITFAM GVVIGPFMMN LFDSSHGSGW RNAFLIPVPF CLVNASIMLA 180
181 DMY
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|
Region B: Residues: [509-632] |
1 11 21 31 41 51
| | | | | |
1 MNSVISMSLQ GDKRLIWTMI GISFCFAALM CIIPFGTTYF IIVLNLSTLQ LAERLSPFFF 60
61 SIVLGYFSVS YFWKSKGQNF LLKFVLSGAT LLLYVALMGV SLNLPVWKQY ICLSLPFLGS 120
121 SMIL
|
| Detection Method: | |
| Confidence: | 7.39794 |
| Match: | 1ja5A_ |
| Description: | No description for 1ja5A_ was found. |
|
Region A: Residues: [428-508] |
1 11 21 31 41 51
| | | | | |
1 SVKSTLYGRP TPTLWKRFKN TLLSPDLYEI LTLTLFLLCF VQVTSLDLTG LKNNTMIQAL 60
61 LFSVIIVCGI LFFLIETSDT Y
|
| Detection Method: | |
| Confidence: | 7.39794 |
| Match: | 1ja5A_ |
| Description: | No description for 1ja5A_ was found. |
|
Region A: Residues: [633-768] |
1 11 21 31 41 51
| | | | | |
1 TLLSNLYHEY HEQRKSPISG SIVYCFGAVG GTVGISLGGY VFHKTLIKLM HEKVMPFSKQ 60
61 GYLKKDLLKI IKHATESSDW VHESAPKFVF QTLIECYLQA CRNVFKLSTL FFTITVVAIF 120
121 IFNRIHCRSQ NCLSLS
|
| Detection Method: | |
| Confidence: | 3.30103 |
| Match: | 1kplA_ |
| Description: | Clc chloride channel |
Matching Structure (courtesy of the PDB): |
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