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View Structure Prediction Details

Protein: STE5
Organism: Saccharomyces cerevisiae
Length: 917 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STE5.

Description E-value Query
Range
Subject
Range
gi|311161 - gi|311161|gb|AAA35108.1| STE5 [Saccharomyces cerevisiae]
0.0 [1..917] [1..916]

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Predicted Domain #1
Region A:
Residues: [1-917]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMETPTDNIV SPFHNFGSST QYSGTLSRTP NQIIELEKPS TLSPLSRGKK WTEKLARFQR  60
   61 SSAKKKRFSP SPISSSTFSF SPKSRVTSSN SSGNEDGNLM NTPSTVSTDY LPQHPHRTSS 120
  121 LPRPNSNLFH ASNSNLSRAN EPPRAENLSD NIPPKVAPFG YPIQRTSIKK SFLNASCTLC 180
  181 DEPISNRRKG EKIIELACGH LSHQECLIIS FGTTSKADVR ALFPFCTKCK KDTNKAVQCI 240
  241 PENDELKDIL ISDFLIHKIP DSELSITPQS RFPPYSPLLP PFGLSYTPVE RQTIYSQAPS 300
  301 LNPNLILAAP PKERNQIPQK KSNYTFLHSP LGHRRIPSGA NSILADTSVA LSANDSISAV 360
  361 SNSVRAKDDE TKTTLPLLRS YFIQILLNNF QEELQDWRID GDYGLLRLVD KLMISKDGQR 420
  421 YIQCWCFLFE DAFVIAEVDN DVDVLEIRLK NLEVFTPIAN LRMTTLEASV LKCTLNKQHC 480
  481 ADLSDLYIVQ NINSDESTTV QKWISGILNQ DFVFNEDNIT STLPILPIIK NFSKDVGNGR 540
  541 HETSTFLGLI NPNKVVEVGN VHDNDTVIIR RGFTLNSGEC SRQSTVDSIQ SVLTTISSIL 600
  601 SLKREKPDNL AIILQIDFTK LKEEDSLIVV YNSLKALTIK FARLQFCFVD RNNYVLDYGS 660
  661 VLHKIDSLDS ISNLKSKSSS TQFSPIWLKN TLYPENIHEH LGIVAVSNSN MEAKKSILFQ 720
  721 DYRCFTSFGR RRPNELKIKV GYLNVDYSDK IDELVEASSW TFVLETLCYS FGLSFDEHDD 780
  781 DDEEDNDDST DNELDNSSGS LSDAESTTTI HIDSPFDNEN ATANMVNDRN LLTEGEHSNI 840
  841 ENLETVASSV QPALIPNIRF SLHSEEEGTN ENENENDMPV LLLSDMDKGI DGITRRSSFS 900
  901 SLIESGNNNC PLHMDYI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [134-271]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNLSRANEPP RAENLSDNIP PKVAPFGYPI QRTSIKKSFL NASCTLCDEP ISNRRKGEKI  60
   61 IELACGHLSH QECLIISFGT TSKADVRALF PFCTKCKKDT NKAVQCIPEN DELKDILISD 120
  121 FLIHKIPDSE LSITPQSR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1u6gB
Description: Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [272-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPPYSPLLPP FGLSYTPVER QTIYSQAPSL NPNLILAAPP KERNQIPQKK SNYTFLHSP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [331-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGHRRIPSGA NSILADTSVA LSANDSISAV SNSVRAKDDE TKTTLPLLRS YFIQILLNNF  60
   61 QEELQDWRID GDYGLLRLVD KLMISKDGQR YIQCWCFLFE DAFVIAEVDN DVDVLEIRLK 120
  121 NLEVFTPIAN LRMTTLEASV LKCTLNKQHC ADLSDLYIVQ NINSDESTTV QKWISGILNQ 180
  181 DFVFNEDNIT STLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [525-771]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILPIIKNFSK DVGNGRHETS TFLGLINPNK VVEVGNVHDN DTVIIRRGFT LNSGECSRQS  60
   61 TVDSIQSVLT TISSILSLKR EKPDNLAIIL QIDFTKLKEE DSLIVVYNSL KALTIKFARL 120
  121 QFCFVDRNNY VLDYGSVLHK IDSLDSISNL KSKSSSTQFS PIWLKNTLYP ENIHEHLGIV 180
  181 AVSNSNMEAK KSILFQDYRC FTSFGRRRPN ELKIKVGYLN VDYSDKIDEL VEASSWTFVL 240
  241 ETLCYSF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [772-835]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLSFDEHDDD DEEDNDDSTD NELDNSSGSL SDAESTTTIH IDSPFDNENA TANMVNDRNL  60
   61 LTEG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [836-917]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EHSNIENLET VASSVQPALI PNIRFSLHSE EEGTNENENE NDMPVLLLSD MDKGIDGITR  60
   61 RSSFSSLIES GNNNCPLHMD YI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle