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View Structure Prediction Details

Protein: IPT1
Organism: Saccharomyces cerevisiae
Length: 527 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IPT1.

Description E-value Query
Range
Subject
Range
IPT1_YEAST - Inositolphosphotransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IPT1 PE=1 S...
IPT1 - Inositolphosphotransferase, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), the m...
0.0 [1..527] [1..527]
AUR1_CANAL - Aureobasidin A resistance protein homolog OS=Candida albicans GN=AUR1 PE=3 SV=1
2.0E-86 [88..317] [66..287]
gi|4741885 - gi|4741885|gb|AAD28747.1|AF126178_1 inositolphosphorylceramide synthase; IPC1p [Candida parapsilosis...
1.0E-78 [92..320] [73..293]
gi|4558826 - gi|4558826|gb|AAD22749.1|AF076691_1 aureobasidin-resistance protein; AurA [Aspergillus nidulans]
7.0E-78 [102..320] [110..312]
gi|7144496 - gi|7144496|gb|AAD28748.2|AF126179_1 inositolphosphorylceramide synthase; IPC1p [Candida tropicalis]
4.0E-76 [87..315] [64..284]
gi|4558828 - gi|4558828|gb|AAD22750.1|AF076692_1 aureobasidin-resistance protein; Aur1 homolog; Aur1 [Aspergillus...
2.0E-75 [99..320] [106..312]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-74 [88..320] [53..277]
gi|2992150 - gi|2992150|dbj|BAA25320.1| Aur1-C [Shuttle vector pAUR112]
gi|2992148 - gi|2992148|dbj|BAA25319.1| Aur1-C [Shuttle vector pAUR101]
gi|2992152 - gi|2992152|dbj|BAA25321.1| Aur1-C [Shuttle vector pAUR123]
6.0E-74 [88..320] [53..277]

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Predicted Domain #1
Region A:
Residues: [1-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVIFSLASF VKNMYNASLN QRNLISLPFN FMLNFAPVFI WLSIFKRAGL IPIRLRPDIH  60
   61 SKFAFFADQF LFGDYWHELT VQLPDNTSKL FFWSFISSSA FLLVFLICIP FAIWYYIYYI 120
  121 KHVNYNLLEW FANIFHYPCK RKQRPIQKRF RTIFIPFALP LFTFVILNID HFFAYQSDAN 180
  181 FTKTKDLLAW FSYVILHLTA PILTAVYLYV FQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [213-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPGTLKCFSF ALGLQNIAGV LTHLLVPMAS PWFTHLYGID DTEHVNYTQE GFAAGLIRVD  60
   61 SHLGTHLNTK GFHMSPIVFG AVPSLHSAIA FQCFLFLVSR STSLKHRFSN AGGFTMHNND 120
  121 SSTFKLSEED SEDEGDNSIP PTIGPNDLEM EPLGTVEPVD ISNERSSSPS SSFTVSSNER 180
  181 STGGGDGSII NSNGNKKPLQ FVHLYDEDTN FTNKWIFKIV NDGFIPKFWA ILYIILQWWA 240
  241 TMYLDHHYRF DLFVGVLYAM TSFIIINWFV LQPKVLKKWI HIRLGDKVDT RNEARTFGMR 300
  301 VFCGTKMEWF FDPLA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 2.721246
Match: PF01569
Description: PAP2 superfamily

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [199-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAPILTAVYL YVFQPPGTLK CFSFALGLQN IAGVLTHLLV PMASPWFTHL YGIDDTEHVN  60
   61 YTQEGFAAGL IRVDSHLGTH LNTKGFHMSP IVFGAVPSLH SAIAFQCFLF LVSRSTSLKH 120
  121 RFSNAGGFTM HNNDSSTFKL SEEDSEDEGD NSIPPTIGPN DLEMEPLGTV EPVDISNERS 180
  181 SSPSSSFTVS SNERSTGGGD GSIINSNGNK KPLQFVHLYD EDTNFTNKWI FKIVNDGFIP 240
  241 KFWAILYIIL QWWATMYLDH HYRFDLFVGV LYAMTSFIII NWFVLQPKVL KKWIHIRLGD 300
  301 KVDTRNEART FGMRVFCGTK MEWFFDPLA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.12
Match: 2a96A
Description: No description for 2a96A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle