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View Structure Prediction Details

Protein: ENA2
Organism: Saccharomyces cerevisiae
Length: 1091 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENA2.

Description E-value Query
Range		 Subject
Range
AT1A1_RAT - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Rattus norvegicus GN=Atp1a1 PE=1 SV=1
 0.0 [2..1059] [28..1021]
ATP1A3 - ATPase, Na+/K+ transporting, alpha 3 polypeptide
 0.0 [5..1059] [21..1011]
AT1A1_HORSE - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Equus caballus GN=ATP1A1 PE=3 SV=1
 0.0 [2..1059] [26..1019]
AT1A3_CHICK - Sodium/potassium-transporting ATPase subunit alpha-3 OS=Gallus gallus GN=ATP1A3 PE=2 SV=1
 0.0 [3..1059] [16..1008]
gi|1364218 - gi|1364218|emb|CAA26582.1| unnamed protein product [Ovis aries]
 0.0 [2..1059] [21..1014]
ATN1_YEAST - Sodium transport ATPase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ENA1 PE=1 SV=1
ENA1 - P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
 0.0 [1..1091] [1..1091]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 0.0 [2..1059] [26..1019]

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Predicted Domain #1
Region A:
Residues: [1-56] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEGTVKENN NEEFNAYHTL TTEEAAEFIG TSLTEGLTQD ESLRRLKAVG ENTLGD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [128-258] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNAHVIRNGK SETINSKDVV PGDICLVKVG DTIPADLRLI ETKNFDTDES LLTGESLPVS  60
   61 KDANLVFGKE EETSVGDRLN LAFSSSAVVK GRAKGIVIKT ALNSEIGKIA KSLQGDSGLI 120
  121 SRDPSKSWLQ N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1906.9897
Match: 1eulA_
Description: Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #2
Region A:
Residues: [57-117] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTKIDYKAMV LHQVCNAMIM VLVISMAISF AVRDWITGGV ISFVIAVNVL IGLVQEYKAT  60
   61 K

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [259-336] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TWISTKKVTG AFLGTNVGTP LHRKLSKLAV LLFWIAVLFA IIVMASQKFD VDKRVAIYAI  60
   61 CVALSMIPSS LVVVLTIT

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [808-1091] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDNIQKFVL QLLAENVAQA LYLIIGLVFR DENGKSVFPL SPVEVLWIIV VTSCFPAMGL  60
   61 GLEKAAPDLM DRPPHDSEVG IFTWEVIIDT FAYGIIMTGS CMASFTGSLY GINSGRLGHD 120
  121 CDGTYNSSCR DVYRSRSAAF ATMTWCALIL AWEVVDMRRS FFRMHPDTDS PVKEFFRSIW 180
  181 GNQFLFWSII FGFVSAFPVV YIPVINDKVF LHKPIGAEWG LAIAFTIAFW IGAELYKCGK 240
  241 RRYFKTQRAH NPENDLESNN KRDPFEAYST STTIHTEVNI GIKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1906.9897
Match: 1eulA_
Description: Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #3
Region A:
Residues: [118-127] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TMNSLKNLSS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [337-376] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVGAAVMVS RNVIVRKLDS LEALGAVNDI CSDKTGTLTQ

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [651-807] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRNETAGAVK KFHQAGINVH MLTGDFVGTA KAIAQEVGIL PTNLYHYSQE IVDSMVMTGS  60
   61 QFDGLSEEEV DDLPVLPLVI ARCSPQTKVR MIEALHRRKK FCAMTGDGVN DSPSLKMANV 120
  121 GIAMGINGSD VSKEASDIVL SDDNFASILN AVEEGRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1906.9897
Match: 1eulA_
Description: Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #4
Region A:
Residues: [377-650] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKMLARQIWI PRFGTITISN SDDPFNPNEG NVSLIPRFSP YEYSHNEDGD VGILQNFKDR  60
   61 LYEKDLPEDI DMDLFQKWLE TATLANIATV FKDDATDCWK AHGDPTEIAI QVFATKMDLP 120
  121 HNALTGEKST NQSNENDQSS LSQHNEKPGS AQFEHIAEFP FDSTVKRMSS VYYNNHNETY 180
  181 NIYGKGAFES IISCCSSWYG KDGVKITPLT DCDVETIRKN VYSLSNEGLR VLGFASKSFT 240
  241 KDQVNDDQLK NITSNRATAE SDLVFLGLIG IYDP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1906.9897
Match: 1eulA_
Description: Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle