YRC Public Data Repository - Protein Structure Prediction

Protein:	GAL3
Organism:	Saccharomyces cerevisiae
Length:	520 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAL3.

Description	E-value	Query Range	Subject Range
GAL3_YEAST - Protein GAL3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAL3 PE=1 SV=2 gi\|151941998 - gi\|151941998\|gb\|EDN60354.1\| galactose metabolism-related protein [Saccharomyces cerevisiae YJM789] GAL3 - Transcriptional regulator involved in activation of the GAL genes in response to galactose; forms a ...	0.0	[1..520]	[1..520]
gi\|171567\|gb\|AAA... - gal1 gi\|171567 - gi\|171567\|gb\|AAA34631.1\| gal1	0.0	[5..519]	[11..527]
GAL1_KLULA - Galactokinase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-... GAL1_KLULA - Galactokinase OS=Kluyveromyces lactis GN=GAL1 PE=2 SV=2	0.0	[4..519]	[2..503]
SPBPB2B2.13 - galactokinase Gal1 GAL1_SCHPO - Galactokinase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gal1 PE=3 SV=1	0.0	[4..519]	[3..515]
GAL1_CANAX - Galactokinase OS=Candida albicans GN=GAL1 PE=3 SV=1	0.0	[4..518]	[2..509]
GAL1_CANPA - Galactokinase OS=Candida parapsilosis GN=GAL1 PE=3 SV=1	0.0	[4..519]	[2..495]
GALK1_ARATH - Galactokinase OS=Arabidopsis thaliana GN=GAL1 PE=1 SV=2	4.0E-96	[4..518]	[8..494]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	7.0E-96	[4..518]	[8..494]

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Predicted Domain #1

Region A:
Residues: [1-44]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTNVPIFSS PVRDLPRSFE QKHLAVVDAF FQTYHVKPDF IARS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [71-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLCAVKILDE KNPSITLTNA DPKFAQRKFD LPLDGSYMAI DPSVSEWSNY FKCGLHVAHS  60
   61 YLKKIAPERF NNTPLVGAQI FCQSDIPTGG GLSSAFTCAA ALATIRANMG KNFDISKKDL 120
  121 TRITAVAEHY VGVNN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.218487
Match:	1kkhA_
Description:	Mevalonate kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [45-70]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGRVNLIGEH IDYCDFSVLP LAIDVD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [206-372]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGMDQATSVY GEEDHALYVE FRPKLKATPF KFPQLKNHEI SFVIANTLVK SNKFETAPTN  60
   61 YNLRVIEVTV AANALATRYS VALPSHKDNS NSERGNLRDF MDAYYARYEN QAQPWNGDIG 120
  121 TGIERLLKML QLVEESFSRK KSGFTVHEAS TALNCSREEF TRDYLTT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.218487
Match:	1kkhA_
Description:	Mevalonate kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [373-520]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPVRFQVLKL YQRAKHVYSE SLRVLKALKM MTSATFHTDE DFFTDFGRLM NESQASCDKL  60
   61 YECSCIETNQ ICSIALANGS FGSRLTGAGW GGCTIHLVPS GANGNVEQVR KALIEKFYNV 120
  121 RYPDLTDEEL KDAIIVSKPA LGTCLYEQ

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	14.1
Match:	1kvkA
Description:	Mevalonate kinase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits