YRC Public Data Repository - Protein Structure Prediction

Protein:	PHO13
Organism:	Saccharomyces cerevisiae
Length:	312 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHO13.

Description	E-value	Query Range	Subject Range
CG5567-PA - This gene is referred to in FlyBase by the symbol Dmel\CG5567 (CG5567, FBgn0036760). It is a protein...	2.0E-60	[1..312]	[16..326]
PGP1A_ARATH, PGP... - Phosphoglycolate phosphatase 1B, chloroplastic OS=Arabidopsis thaliana GN=PGLP1B PE=1 SV=1, Phosphog...	1.0E-58	[1..305]	[54..355]
gi\|151941772 - gi\|151941772\|gb\|EDN60128.1\| p-nitrophenyl phosphatase [Saccharomyces cerevisiae YJM789] PHO13 - Alkaline phosphatase specific for p-nitrophenyl phosphate; also has protein phosphatase activity PNPP_YEAST - 4-nitrophenylphosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHO13 PE=1 SV=2	1.0E-57	[1..312]	[1..312]
pho2 - 4-nitrophenylphosphatase PNPP_SCHPO - 4-nitrophenylphosphatase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pho2 PE=4 SV=2	4.0E-54	[8..306]	[2..296]
gi\|159491082, gi... - gi\|28316388\|dbj\|BAC56941.1\| phosphoglycolate phosphatase precursor [Chlamydomonas reinhardtii], gi\|1...	5.0E-53	[1..312]	[23..327]
PDXP - pyridoxal (pyridoxine, vitamin B6) phosphatase	5.0E-52	[17..310]	[12..296]

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Predicted Domain #1

Region A:
Residues: [1-80]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAQQGVPIK ITNKEIAQEF LDKYDTFLFD CDGVLWLGSQ ALPYTLEILN LLKQLGKQLI  60
   61 FVTNNSTKSR LAYTKKFASF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [81-167]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIDVKEEQIF TSGYASAVYI RDFLKLQPGK DKVWVFGESG IGEELKLMGY ESLGGADSRL  60
   61 DTPFDAAKSP FLVNGLDKDV SCVIAGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.522879
Match:	1jud__
Description:	L-2-Haloacid dehalogenase, HAD
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [168-312]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTKVNYHRLA VTLQYLQKDS VHFVGTNVDS TFPQKGYTFP GAGSMIESLA FSSNRRPSYC  60
   61 GKPNQNMLNS IISAFNLDRS KCCMVGDRLN TDMKFGVEGG LGGTLLVLSG IETEERALKI 120
  121 SHDYPRPKFY IDKLGDIYTL TNNEL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.522879
Match:	1jud__
Description:	L-2-Haloacid dehalogenase, HAD
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits