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View Structure Prediction Details

Protein: ACK1
Organism: Saccharomyces cerevisiae
Length: 623 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACK1.

Description E-value Query
Range
Subject
Range
gi|84375186, gi|... - gi|84394204|ref|ZP_00992934.1| hypothetical protein V12B01_19651 [Vibrio splendidus 12B01], gi|84375...
252.0 [0..217] [623..52]
gi|69255787, gi|... - gi|69255787|ref|ZP_00605529.1| Sel1-like repeat [Magnetococcus sp. MC-1], gi|68248152|gb|EAN30235.1|...
236.0 [0..217] [623..389]
gi|60360536 - gi|60360536|dbj|BAD90512.1| mKIAA4137 protein [Mus musculus]
234.0 [0..128] [622..60]
gi|73964368 - gi|73964368|ref|XP_537530.2| PREDICTED: similar to sel-1 suppressor of lin-12-like [Canis familiaris...
229.0 [0..128] [622..17]
gi|88934891, gi|... - gi|88934891|ref|ZP_01140530.1| Sel1-like repeat [Geobacter uraniumreducens Rf4], gi|88918355|gb|EAR3...
228.0 [0..218] [622..123]
gi|6851089, gi|5... - gi|6851089|gb|AAF29413.1|AF052059_1 SEL1L [Homo sapiens], sp|Q9UBV2|SE1L_HUMAN Sel-1 homolog precurs...
227.0 [0..130] [622..19]
gi|53753948, gi|... - gi|54294116|ref|YP_126531.1| hypothetical protein lpl1180 [Legionella pneumophila str. Lens], gi|537...
225.0 [0..172] [622..11]
SE1L1_MESAU - Protein sel-1 homolog 1 OS=Mesocricetus auratus GN=Sel1l PE=2 SV=1
223.0 [0..128] [622..17]

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Predicted Domain #1
Region A:
Residues: [1-145]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNQGQPQPN LYDKHINMFP PARARESSHK LGNANSDRHG LPAQNIVPAP YPVDDSIVEL  60
   61 TPAIPFTSPS SSSSLSLPLS ALNFTDGNAD GGQLGTPVTI NSNNGMDIFN SKPTGEIGYA 120
  121 NNGTNSTGSR YELPFNFSST KESLG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [146-361]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPAVQDASIS SGNRISESVR DNSAPPPYEE SESRILQEKV YRTEEKAPIR PLNNNPVPPQ  60
   61 KINQPPTGSA KTDDNGSSGG EDKLSSYSPE ALAFYQVYKK TITDSSKFTP EIQMQWCETL 120
  121 LTYAFNEDFI SQYNINAEKL KRSLKPEEML KNQKVILEHS FKVLTKLITL KWPPAMYLMG 180
  181 TLYSHQPYLP IKNKNIVIKN DEKALEYYCK AAKLNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [362-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDACYRAGVC FEYQRGTSSL DPSPTKEQCI KKAFQYYQHG AEVCSNSACM YKLGMSHLYG  60
   61 LNMQKTDVLL AIKWFDKAAQ KGDSPQTLYE LGKIYEFSVL PPEIQNLLFA NGIRKDSQLA 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [482-623]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKYYQQCAKD FEYPLAQWKL GNCYEFGDLG LPVVAKKSIY WYSKAAAAQP KGNPMAMLSL  60
   61 SGWYLTGAPN ILKPNNKEAF NWALKSSKCS DGKLARTEFA LGFYYEKGVG CEVDLDLAKQ 120
  121 YYQRAARMGF RKAVDALRSL TN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1ihgA
Description: Cyclophilin 40; Cyclophilin 40 isomerase domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle