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View Structure Prediction Details

Protein: YDL199C
Organism: Saccharomyces cerevisiae
Length: 687 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDL199C.

Description E-value Query
Range
Subject
Range
YDL199C - Putative transporter, member of the sugar porter family
YD199_YEAST - Putative metabolite transport protein YDL199C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
0.0 [1..687] [1..687]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
0.0 [43..588] [1..547]
GTR3_CANLF - Solute carrier family 2, facilitated glucose transporter member 3 OS=Canis lupus familiaris GN=SLC2A...
0.0 [115..594] [5..491]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPPLNMSRS NKPLTQEANS SAHIDRAHQL AQDFNSKQDD TALTSLPHKN PDIFRFENNI  60
   61 TAHSSRRGSL YRDSDATVVL PLSEH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.471 d.58.3 Protease propeptides/inhibitors
View Download 0.312 d.110.1 Profilin (actin-binding protein)
View Download 0.268 b.34.2 SH3-domain
View Download 0.254 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.244 b.80.3 Cell-division inhibitor MinC, C-terminal domain
View Download 0.240 b.101.1 Ribonuclease domain of colicin E3
View Download 0.223 c.98.1 MurE/MurF N-terminal domain
View Download 0.218 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.210 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.205 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.205 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.202 d.58.2 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain

Predicted Domain #2
Region A:
Residues: [86-304]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPRLSMDDPY RQLLQQAEIS QLRSKKKRHS SRVLRTSFIS FVVLVSSLSG LDQGLISGNV  60
   61 MTLSFQKYFH YPLTSPLGNI VSIVNLGAFM ASLFVYSGIL EPCSRKKMLQ ISTMIYSLGA 120
  121 IVQVLALNQW CLLLGRFLLG VGMGFAFSMV IIYQFEFPLP CIRKRTLISI QCVSSVIAYS 180
  181 FGIWINCAFR YLGFAWRYPL STHVALGIIL NLMSFYLIL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [349-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLKSHLQKNS YPYAYILKDF SSIIKLLIGF QLLTRTNGVD AFLYYSPLIL QQMGRGERKS  60
   61 IYLTGLNALI YSIVILAYVP LVLRKRKEKT NVLLGSIVMC ALLFTISFTD WFPKSTTRYI 120
  121 SILFAVFLFT HFISWDSIGW VMTIELLPHL SQAPVILLVS NFYWIFKWFV SLITPILIDR 180
  181 LSWKFYLIPS LSSFISIIFV LKIFPIETR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 148.0
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transporter activity 3.3426261924492 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.29689809004391 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
ion transmembrane transporter activity 1.94035843948137 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 1.6904339767429 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
cation transmembrane transporter activity 1.5181741634556 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 1.34681686321591 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 1.34681686321591 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
binding 0.805286077372817 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [305-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPSWLLKQK NDVEALVLIS NVFDDGNFEE NQTQLKFRVL KRDI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [558-623]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DERLDSDDDS TGNGSGNHDD VFDDTGSEFS SSPSFSAYQI NTLGSSIKQN NQAYSSIQNE  60
   61 QILPKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 148.0
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted Domain #4
Region A:
Residues: [624-687]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNLSNQTHGS AQNVYFITSD SGPSRTGEFF SFHNRTDPNI SDNIAANKPS SGGGQNSPGD  60
   61 MAVA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.490 a.4.5 "Winged helix" DNA-binding domain
View Download 0.483 d.10.1 DNA-binding domain
View Download 0.444 d.15.7 Immunoglobulin-binding domains
View Download 0.424 a.4.5 "Winged helix" DNA-binding domain
View Download 0.396 a.144.1 PABC (PABP) domain
View Download 0.290 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.268 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.261 g.7.1 Snake toxin-like
View Download 0.203 b.4.1 HSP40/DnaJ peptide-binding domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle