YRC Public Data Repository - Protein Structure Prediction

Protein:	RPN5
Organism:	Saccharomyces cerevisiae
Length:	445 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPN5.

Description	E-value	Query Range	Subject Range
gi\|73965259 - gi\|73965259\|ref\|XP_537584.2\| PREDICTED: similar to 26S proteasome non-ATPase regulatory subunit 12 (...	368.0	[0..7]	[443..14]
PSD12_PONAB - 26S proteasome non-ATPase regulatory subunit 12 OS=Pongo abelii GN=PSMD12 PE=2 SV=3 PSD12_PONPY - 26S proteasome non-ATPase regulatory subunit 12 - Pongo pygmaeus (Orangutan)	367.0	[0..7]	[443..14]
gi\|123985956, gi... - gi\|168275714\|dbj\|BAG10577.1\| 26S proteasome non-ATPase regulatory subunit 12 [synthetic construct], ... gi\|114670121 - gi\|114670121\|ref\|XP_511639.2\| PREDICTED: proteasome 26S non-ATPase subunit 12 [Pan troglodytes] gi\|109117036 - gi\|109117036\|ref\|XP_001116817.1\| PREDICTED: proteasome 26S non-ATPase subunit 12 isoform 2 [Macaca m... PSMD12 - proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	367.0	[0..7]	[443..14]
PSD12_BOVIN - 26S proteasome non-ATPase regulatory subunit 12 OS=Bos taurus GN=PSMD12 PE=2 SV=3	365.0	[0..7]	[443..14]
gi\|12857304 - gi\|12857304\|dbj\|BAB30969.1\| unnamed protein product [Mus musculus]	365.0	[0..7]	[443..14]
gi\|54400716, gi\|... - gi\|54400716\|ref\|NP_001005875.1\| proteasome 26S non-ATPase subunit 12 [Rattus norvegicus], gi\|5373354...	365.0	[0..7]	[443..14]
gi\|53136554, gi\|... - gi\|71897101\|ref\|NP_001025877.1\| proteasome 26S non-ATPase subunit 12 [Gallus gallus], gi\|53136554\|em...	363.0	[0..7]	[443..14]

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Predicted Domain #1

Region A:
Residues: [1-101]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRDAPIKAD KDYSQILKEE FPKIDSLAQN DCNSALDQLL VLEKKTRQAS DLASSKEVLA  60
   61 KIVDLLASRN KWDDLNEQLT LLSKKHGQLK LSIQYMIQKV M

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	13.64
Match:
Description:	No description for 1hz4A was found.

Predicted Domain #2

Region A:
Residues: [102-222]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYLKSSKSLD LNTRISVIET IRVVTENKIF VEVERARVTK DLVEIKKEEG KIDEAADILC  60
   61 ELQVETYGSM EMSEKIQFIL EQMELSILKG DYSQATVLSR KILKKTFKNP KYESLKLEYY 120
  121 N

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	13.64
Match:
Description:	No description for 1hz4A was found.

Predicted Domain #3

Region A:
Residues: [223-370]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLVKISLHKR EYLEVAQYLQ EIYQTDAIKS DEAKWKPVLS HIVYFLVLSP YGNLQNDLIH  60
   61 KIQNDNNLKK LESQESLVKL FTTNELMRWP IVQKTYEPVL NEDDLAFGGE ANKHHWEDLQ 120
  121 KRVIEHNLRV ISEYYSRITL LRLNELLD

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	13.64
Match:
Description:	No description for 1hz4A was found.

Predicted Domain #4

Region A:
Residues: [371-445]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTESQTETYI SDLVNQGIIY AKVNRPAKIV NFEKPKNSSQ LLNEWSHNVD ELLEHIETIG  60
   61 HLITKEEIMH GLQAK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.914	N/A	N/A	d.58.4	Dimeric alpha+beta barrel

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits