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View Structure Prediction Details

Protein: CRD1
Organism: Saccharomyces cerevisiae
Length: 283 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CRD1.

Description E-value Query
Range
Subject
Range
CRD1 - Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membr...
CRD1_YEAST - Cardiolipin synthase (CMP-forming) OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CRD1 ...
3.0E-56 [1..283] [1..283]
CCDS830.1_1 - null
CEPT1 - choline/ethanolamine phosphotransferase 1
gi|114558962, gi... - gi|114558966|ref|XP_001161701.1| PREDICTED: choline/ethanolaminephosphotransferase isoform 7 [Pan tr...
5.0E-29 [55..270] [62..303]
DIPPS_AQUAE - Bifunctional IPC transferase and DIPP synthase OS=Aquifex aeolicus (strain VF5) GN=spsI PE=1 SV=1
gi|7429848 - pir||H70418 glucose-1-phosphate thymidylyltransferase - Aquifex aeolicus
6.0E-27 [40..225] [231..422]
gi|5458457, gi|7... - pir||D75080 glucose-1-phosphate thymidylyltransferase related protein PAB2433 - Pyrococcus abyssi (s...
gi|5458457, gi|1... - gi|5458457|emb|CAB49945.1| CDP-alcohol phosphatidyltransferase [Pyrococcus abyssi GE5], gi|14521239|...
1.0E-26 [40..223] [225..414]
DIPPS_PYRFU - Bifunctional IPC transferase and DIPP synthase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 ...
1.0E-26 [40..225] [234..425]
gi|7429847 - pir||E71065 hypothetical protein PH1219 - Pyrococcus horikoshii
gi|14591039, gi|... - gi|3257636|dbj|BAA30319.1| 423aa long hypothetical protein [Pyrococcus horikoshii OT3], gi|14591039|...
2.0E-26 [40..223] [225..414]
CLS_ARATH - Cardiolipin synthase (CMP-forming), mitochondrial OS=Arabidopsis thaliana GN=CLS PE=1 SV=1
3.0E-25 [32..276] [102..333]
PSS_MYCLE - CDP-diacylglycerol--serine O-phosphatidyltransferase OS=Mycobacterium leprae GN=pssA PE=3 SV=1
PSS_MYCLE - CDP-diacylglycerol--serine O-phosphatidyltransferase OS=Mycobacterium leprae (strain TN) GN=pssA PE=...
gi|221229555, gi... - gi|221229555|ref|YP_002502971.1| putative CDP-diacylglycerol-serine o-phosphatidyltransferase [Mycob...
1.0E-24 [57..281] [3..221]
gi|25288732, gi|... - pir||AG2715 phosphatidylglycerophosphate synthase pgsA [imported] - Agrobacterium tumefaciens (strai...
gi|17739526, gi|... - gi|17935035|ref|NP_531825.1| phosphatidylglycerophosphate synthase [Agrobacterium tumefaciens str. C...
2.0E-24 [65..280] [3..191]

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Predicted Domain #1
Region A:
Residues: [1-58]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQMVPIYSC SALLRRTIPK RPFYHVLSGL TVRFKVNPQL NYNLFRDLTR REYATNPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.694 a.4.5 "Winged helix" DNA-binding domain
View Download 0.677 a.60.2 RuvA domain 2-like
View Download 0.647 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.695 d.47.1 Ribosomal protein L11, N-terminal domain
View Download 0.695 d.47.1 Ribosomal protein L11, N-terminal domain
View Download 0.694 a.4.5 "Winged helix" DNA-binding domain
View Download 0.677 a.60.2 RuvA domain 2-like
View Download 0.661 a.4.5 "Winged helix" DNA-binding domain
View Download 0.661 a.4.5 "Winged helix" DNA-binding domain
View Download 0.647 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.624 a.4.5 "Winged helix" DNA-binding domain
View Download 0.606 a.4.1 Homeodomain-like
View Download 0.555 a.4.1 Homeodomain-like
View Download 0.546 a.4.1 Homeodomain-like
View Download 0.524 a.4.1 Homeodomain-like
View Download 0.500 a.60.1 SAM/Pointed domain
View Download 0.486 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.454 a.5.2 UBA-like
View Download 0.450 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.423 a.144.1 PABC (PABP) domain
View Download 0.392 a.4.5 "Winged helix" DNA-binding domain
View Download 0.385 a.65.1 Annexin
View Download 0.381 a.112.1 Description not found.
View Download 0.372 a.4.1 Homeodomain-like
View Download 0.344 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.315 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.312 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.286 a.4.5 "Winged helix" DNA-binding domain
View Download 0.278 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.273 a.4.1 Homeodomain-like
View Download 0.266 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.264 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.249 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.244 a.39.1 EF-hand
View Download 0.240 a.64.1 Saposin
View Download 0.230 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.229 a.22.1 Histone-fold
View Download 0.226 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.213 a.36.1 Signal peptide-binding domain
View Download 0.209 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.202 a.5.6 Hypothetical protein MTH1615
View Download 0.201 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.201 g.1.1 Insulin-like
View Download 0.201 c.102.1 Cell-division inhibitor MinC, N-terminal domain

Predicted Domain #2
Region A:
Residues: [59-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTPHIKSKLL NIPNILTLSR IGCTPFIGLF IITNNLTPAL GLFAFSSITD FMDGYIARKY  60
   61 GLKTIAGTIL DPLADKLLMI TTTLALSVPS GPQIIPVSIA AIILGRDVLL AISALFIRYS 120
  121 TLKLKYPGRV AWNSYWDIVR YPSAEVRPSQ LSKWNTFFQM VYLGSGVLLL LYEKEEGCEK 180
  181 TEEDFEDRKQ DFQKAFSYLG YVTATTTIMS GVSYALKRNA FKLLK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 28.585027
Match: PF01066
Description: CDP-alcohol phosphatidyltransferase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle