YRC Public Data Repository - Protein Structure Prediction

Protein:	TRM3
Organism:	Saccharomyces cerevisiae
Length:	1436 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRM3.

Description	E-value	Query Range	Subject Range
TRM3_YEAST - tRNA (guanosine(18)-2'-O)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)... TRM3 - 2'-O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine nucleotide at posit...	0.0	[1..1436]	[1..1436]
gi\|221312229 - gi\|221312229\|ref\|ZP_03594034.1\| hypothetical protein BsubsN3_00495 [Bacillus subtilis subsp. subtili... gi\|221317163 - gi\|221317163\|ref\|ZP_03598457.1\| hypothetical protein BsubsJ_00500 [Bacillus subtilis subsp. subtilis... gi\|221321426 - gi\|221321426\|ref\|ZP_03602720.1\| hypothetical protein BsubsS_00500 [Bacillus subtilis subsp. subtilis... YACO_BACSU - Putative TrmH family tRNA/rRNA methyltransferase YacO OS=Bacillus subtilis GN=yacO PE=3 SV=2 YACO_BACSU - Putative TrmH family tRNA/rRNA methyltransferase YacO OS=Bacillus subtilis (strain 168) GN=yacO PE=3...	7.0E-54	[1204..1435]	[3..244]
gi\|25316695 - pir\|\|A83664 tRNA/rRNA methyltransferase BH0113 [imported] - Bacillus halodurans (strain C-125) gi\|15612676, gi\|... - gi\|15612676\|ref\|NP_240979.1\| tRNA/rRNA methyltransferase [Bacillus halodurans C-125], gi\|10172725\|db...	8.0E-53	[1205..1435]	[2..243]
gi\|25316730 - pir\|\|F98035 tRNA (guanosine-2'-O-)-methyltransferase (EC 2.1.1.34) [imported] - Streptococcus pneumo... gi\|15903354, gi\|... - gi\|15903354\|ref\|NP_358904.1\| tRNA (guanosine-2'-O-)-methyltransferase [Streptococcus pneumoniae R6],...	2.0E-51	[1206..1436]	[15..253]
gi\|221232182, gi... - gi\|221232182\|ref\|YP_002511335.1\| SpoU rRNA methylase family protein [Streptococcus pneumoniae ATCC 7... gi\|15901307, gi\|... - gi\|66876818\|ref\|ZP_00402552.1\| COG0566: rRNA methylases [Streptococcus pneumoniae TIGR4], gi\|1590130... gi\|225854898, gi... - gi\|225854898\|ref\|YP_002736410.1\| RNA methyltransferase, TrmH family, group 3 [Streptococcus pneumoni... gi\|25316718 - pir\|\|F95169 spoU rRNA methylase family protein [imported] - Streptococcus pneumoniae (strain TIGR4)	4.0E-51	[1206..1436]	[4..242]
gi\|62130448, gi\|... - gi\|62182815\|ref\|YP_219232.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica subsp... gi\|56416160, gi\|... - gi\|56416160\|ref\|YP_153235.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica subsp... gi\|238910527 - gi\|238910527\|ref\|ZP_04654364.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... RLMB_SALTY - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Salmonella typhimurium (strain LT2 / SGSC1412 /... lcl\|NC_016856.1_... - [gene=yjfH] [protein=23S rRNA (guanosine-2'-O-)-methyltransferase] [protein_id=YP_005240682.1] [loca... gi\|197365085, gi... - gi\|197365085\|ref\|YP_002144722.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica s... gi\|204927331, gi... - gi\|204927331\|ref\|ZP_03218533.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica sub... gi\|213428664 - gi\|213428664\|ref\|ZP_03361414.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|213582911 - gi\|213582911\|ref\|ZP_03364737.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|194449058, gi... - gi\|194449058\|ref\|YP_002048412.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica s... gi\|194469123, gi... - gi\|194469123\|ref\|ZP_03075107.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica sub... RLMB_SALTY - 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB OS=Salmonella typhimurium GN=rlmB PE=3 SV=1 gi\|194734163, gi... - gi\|194734163\|ref\|YP_002117310.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica su... gi\|197263055, gi... - gi\|197263055\|ref\|ZP_03163129.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica sub... gi\|197287651, gi... - gi\|197287651\|gb\|EDY27042.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|205336077, gi... - gi\|205336077\|gb\|EDZ22841.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|205341078, gi... - gi\|205341078\|gb\|EDZ27842.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|194444737, gi... - gi\|194444737\|ref\|YP_002043624.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica su... gi\|161617640, gi... - gi\|161617640\|ref\|YP_001591605.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica s... gi\|205327237, gi... - gi\|205327237\|gb\|EDZ14001.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... RLMB_SALTY - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Salmonella typhimurium GN=rlmB PE=3 SV=1 gi\|168231407, gi... - gi\|205334208\|gb\|EDZ20972.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|213852966 - gi\|213852966\|ref\|ZP_03382498.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|214003352 - gi\|214003352\|ref\|ZP_03414087.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|224586209, gi... - gi\|224586209\|ref\|YP_002640008.1\| putative tRNA/rRNA methyltransferase [Salmonella enterica subsp. en...	4.0E-51	[1206..1435]	[2..242]
gi\|237703847, gi... - gi\|237703847\|ref\|ZP_04534328.1\| RNA methyltransferase [Escherichia sp. 3_2_53FAA], gi\|226901759\|gb\|E... gi\|227836350, gi... - gi\|227886777\|ref\|ZP_04004582.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli 83972... gi\|115515650, gi... - gi\|117626526\|ref\|YP_859849.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli APEC O1... gi\|124528239, gi... - gi\|124528239\|ref\|ZP_01699563.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli B], gi... gi\|75234271, gi\|... - gi\|75234271\|ref\|ZP_00718659.1\| COG0566: rRNA methylases [Escherichia coli E110019], gi\|193070849\|ref... gi\|191170707, gi... - gi\|75242430\|ref\|ZP_00726192.1\| COG0566: rRNA methylases [Escherichia coli F11], gi\|75236167\|ref\|ZP_0... gi\|75212271, gi\|... - gi\|75212271\|ref\|ZP_00712311.1\| COG0566: rRNA methylases [Escherichia coli B171], gi\|194426679\|ref\|ZP... gi\|190904353, gi... - gi\|75231227\|ref\|ZP_00717634.1\| COG0566: rRNA methylases [Escherichia coli B7A], gi\|191165658\|ref\|ZP_... gi\|73858142, gi\|... - gi\|74314665\|ref\|YP_313084.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Shigella sonnei Ss046], g... gi\|89110900, gi\|... - gi\|89110900\|ref\|AP_004680.1\| 23S rRNA (Gm2251)-methyltransferase [Escherichia coli str. K-12 substr.... gi\|192926325, gi... - gi\|75255907\|ref\|ZP_00727639.1\| COG0566: rRNA methylases [Escherichia coli E22], gi\|193066002\|ref\|ZP_... gi\|188489607, gi... - gi\|75515419\|ref\|ZP_00737576.1\| COG0566: rRNA methylases [Escherichia coli 53638], gi\|188494408\|ref\|Z... gi\|157080504, gi... - gi\|75188891\|ref\|ZP_00702158.1\| COG0566: rRNA methylases [Escherichia coli E24377A], gi\|157158474\|ref... gi\|75198026, gi\|... - gi\|75198026\|ref\|ZP_00708096.1\| COG0566: rRNA methylases [Escherichia coli HS], gi\|157163645\|ref\|YP_0... gi\|83585082, gi\|... - gi\|83585082\|ref\|ZP_00923735.1\| COG0566: rRNA methylases [Escherichia coli 101-1], gi\|194439536\|ref\|Z... gi\|254796199, gi... - gi\|254796199\|ref\|YP_003081036.1\| 23S rRNA (Gm2251)-methyltransferase [Escherichia coli O157:H7 str. ... gi\|254164109, gi... - gi\|254164109\|ref\|YP_003047217.1\| 23S rRNA (Gm2251)-methyltransferase [Escherichia coli B str. REL606... gi\|254037194, gi... - gi\|254037194\|ref\|ZP_04871271.1\| 23S rRNA-methyltransferase [Escherichia sp. 1_1_43], gi\|226840300\|gb... gi\|253775195, gi... - gi\|254290859\|ref\|YP_003056607.1\| 23S rRNA (Gm2251)-methyltransferase [Escherichia coli BL21(DE3)], g... gi\|251787429, gi... - gi\|251787429\|ref\|YP_003001733.1\| hypothetical protein B21_04009 [Escherichia coli BL21], gi\|24237970... gi\|238859752, gi... - gi\|238903287\|ref\|YP_002929083.1\| 23S rRNA (Gm2251)-methyltransferase [Escherichia coli BW2952], gi\|2... gi\|215489524, gi... - gi\|215489524\|ref\|YP_002331955.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli O127... gi\|217326510, gi... - gi\|217326510\|ref\|ZP_03442594.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H... gi\|218358992, gi... - gi\|218551450\|ref\|YP_002385242.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia fergusoni... gi\|218363501, gi... - gi\|218556732\|ref\|YP_002389646.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli IAI1... gi\|218561339, gi... - gi\|218561339\|ref\|YP_002394252.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli S88]... gi\|218430078, gi... - gi\|218692514\|ref\|YP_002400726.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli ED1a... gi\|218354661, gi... - gi\|218697929\|ref\|YP_002405596.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli 5598... gi\|218372863, gi... - gi\|218702877\|ref\|YP_002410506.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli IAI3... gi\|169891461, gi... - gi\|170083626\|ref\|YP_001732946.1\| 23S rRNA (Gm2251)-methyltransferase [Escherichia coli str. K-12 sub... gi\|170517295, gi... - gi\|170679577\|ref\|YP_001746575.1\| RNA methyltransferase [Escherichia coli SMS-3-5], gi\|170517295\|gb\|A... gi\|194417170, gi... - gi\|194434585\|ref\|ZP_03066842.1\| RNA methyltransferase, TrmH family, group 3 [Shigella dysenteriae 10... gi\|195935970 - gi\|195935970\|ref\|ZP_03081352.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli O157:... gi\|208726719, gi... - gi\|208806918\|ref\|ZP_03249255.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H... gi\|208813496, gi... - gi\|208813496\|ref\|ZP_03254825.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H... gi\|208818601, gi... - gi\|208818601\|ref\|ZP_03258921.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H... gi\|209160633, gi... - gi\|209399233\|ref\|YP_002273722.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:... gi\|24054863, gi\|... - gi\|24115535\|ref\|NP_710045.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Shigella flexneri 2a str.... RLMB_ECOL6 - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 70... RLMB_ECO57 - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Escherichia coli O157:H7 GN=rlmB PE=3 SV=1 gi\|30065552, gi\|... - gi\|30065552\|ref\|NP_839723.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Shigella flexneri 2a str.... RLMB_ECOL6 - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Escherichia coli O6 GN=rlmB PE=3 SV=1 EG12483 - 23S rRNA mG2251 2'-O-ribose methyltransferase, SAM-dependent / 23S rRNA mG2251 2'-O-ribose methyltra... RLMB_ECOLI - 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB (EC 2.1.1.-) (23S rRNA Gm2251 2'-O-methyltransfera... gi\|15804769, gi\|... - gi\|15804769\|ref\|NP_290810.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli O157:H7 ... gi\|218434888, gi... - gi\|218707791\|ref\|YP_002415310.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli UMN0... RLMB_SHIFL - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Shigella flexneri GN=rlmB PE=3 SV=1 EG12483 - 23S rRNA mG2251 2'-O-ribose methyltransferase, SAM-dependent / 23S rRNA mG2251 2'-O-ribose methyltra... gi\|91213729, gi\|... - gi\|91213729\|ref\|YP_543715.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli UTI89], ... gi\|189357886, gi... - gi\|189357886\|gb\|EDU76305.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H7 st... gi\|13364633, gi\|... - gi\|15834410\|ref\|NP_313183.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli O157:H7 ... gi\|189368907, gi... - gi\|189368907\|gb\|EDU87323.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H7 st... gi\|110644537, gi... - gi\|110644537\|ref\|YP_672267.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli 536], g... gi\|168766459, gi... - gi\|189364243\|gb\|EDU82662.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H7 st... gi\|110808098, gi... - gi\|110808098\|ref\|YP_691618.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Shigella flexneri 5 str.... gi\|187770173, gi... - gi\|187770173\|gb\|EDU34017.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H7 st... gi\|189001755, gi... - gi\|189001755\|gb\|EDU70741.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H7 st... gi\|189374953, gi... - gi\|189374953\|gb\|EDU93369.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H7 st... gi\|168801835, gi... - gi\|189376090\|gb\|EDU94506.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H7 st... gi\|170021810, gi... - gi\|170021810\|ref\|YP_001726764.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli ATCC... gi\|168751468, gi... - gi\|188014500\|gb\|EDU52622.1\| RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H7 st...	6.0E-51	[1206..1435]	[2..242]
gi\|213021981 - gi\|213021981\|ref\|ZP_03336428.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... RLMB_SALTI - 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB OS=Salmonella typhi GN=rlmB PE=3 SV=1 gi\|29140306, gi\|... - gi\|29144667\|ref\|NP_808009.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica subsp... RLMB_SALTI - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Salmonella typhi GN=rlmB PE=3 SV=1 gi\|16763188 - gi\|16763188\|ref\|NP_458805.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica subsp... gi\|213648977 - gi\|213648977\|ref\|ZP_03379030.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|213417716 - gi\|213417716\|ref\|ZP_03350838.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su...	1.0E-50	[1206..1435]	[2..242]
gi\|25325048 - pir\|\|AD1951 tRNA/rRNA methyltransferase [imported] - Nostoc sp. (strain PCC 7120) gi\|17130505, gi\|... - gi\|17228654\|ref\|NP_485202.1\| tRNA/rRNA methyltransferase [Nostoc sp. PCC 7120], gi\|17130505\|dbj\|BAB7...	1.0E-50	[1186..1435]	[94..321]

Back

Predicted Domain #1

Region A:
Residues: [1-1178]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGGALICKY LPREEQLKLI SDLIQNDSLE EVLELIETSP LDITTDSNIE TPIFEKITEQ  60
   61 VIAYASIDGE AREMFRSSRA EMNKALRTSA QLLCCLPSVW HKFQVWMSYR LNDIISENYK 120
  121 HLFNDNFGKK IVQPFFDSFA EEQNANIKHE NLHLDILSLL HYLEVVYLFD ECKNGISSKC 180
  181 LDFIIVPLLG CNSEEIADSC SKLMRWHIKY LSKCCNTDSN FDKLIWTFIK QLYAEGSQQA 240
  241 WKQKNSLSFL LRFLLAAELS PELITYIKTD AYWRHIQTEL DNDVHEHRKL ALSILKLTIQ 300
  301 KLSSHGITLQ TTFYKCNDLA NIEMLGSWKK FTTLYEMIAL DTSLNQIQAA KQDIIKIFDN 360
  361 EHLHHSWGLI LLSTGLKSSM ESVRKYMMTL MFSITNMSAF SSNLPLLTKT LLPAAMSAHY 420
  421 FDVKGVSCPH GEKLSLFVNN LLSQTTEGIS DILFEILKLL VEKGTSFDPS RIYLSYGILV 480
  481 FFQNNKQKTI NSDHLSLIRK LYDFAAEEEV LETTIQTIYL KFLLYIDPSV SASELLFTLV 540
  541 SHIKLKGGTY KYVEPLFEDY RDLAVSHFDD LQAKENLTTN IGKDTIFDLL ASIIFDFKDI 600
  601 DITPDFLIEV AKSKQDIPVY TSKAVTFLTQ LLSGEPSNGY TYENATALLS YPNFTISTWK 660
  661 SINVNNLFKS VMEKFSLDKF KFFAEIYQKT YECRFDTIEL NFNDLLSLYE MVKKSANQCS 720
  721 RESFKVKDSA YSSYFELLNT FLKTYALNRD SSEGNDDELH ILLRLVDENI NKDNGNYLGN 780
  781 LAVCKLLYFI IDSYIHCSTS VSDDDIFIVK FIFEKFSFIW ECINSERLVL KERDLHLMLI 840
  841 KGLFHPVILY FGSNQYIDTL TSKLEEHAQT IISLSYSRRS LLPLLGSQLR VFMKFYGKLL 900
  901 REDVNYWWLI NIIVGVFKQP QMDVNLYKLK PVISSLFDHK LNNYYIKGDE LYEKVYGPDE 960
  961 ILARVSIIDS ILYANDQLKI RLIEKVTEKT NALYAIKRTD GAEALQRLLQ WQLLLLSLLT1020
 1021 TNEKKLSETS MIRILKSIED ESSPLVRVYK EWFISSKVVD YYKTGNPKFA EDYLFSLLED1080
 1081 HSKPVFVVSA EKICFMVLKD LRNDEKKYGF TQLLDRFICT LVPNAASNKP LVRHFSNSLI1140
 1141 ISLWPTFKAY LSDHTLRNII ENLYSNAKKT QIFGQYRA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [1179-1277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDANIWDLKG DRKLTNMFGG VLKKVTDHDC PYISESVFEK YLQEKDIVPI GTDERSLWLD  60
   61 KRDTNTESVN NANISCDTSP LQTKSGAWET VLDLDNKKS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.69897
Match:	1ipaA_
Description:	RrmH, C-terminal domain; RrmH, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [1278-1436]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDVVTRSELI VVSSLVDKPP NLGGICRLCD VLGVGLLTVQ DIKVKNHPQF KNVAVTADRW  60
   61 MPMEEVALDE IASFMKEKKK EGYTLIGLEQ TDKSVKLDNN FQFPKKSLIL LGTEAFGIPG 120
  121 TLLSELDLCL EIQQFGVIRS MNIQTATAVI VHSYTVQHM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.69897
Match:	1ipaA_
Description:	RrmH, C-terminal domain; RrmH, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [429-616]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHGEKLSLFV NNLLSQTTEG ISDILFEILK LLVEKGTSFD PSRIYLSYGI LVFFQNNKQK  60
   61 TINSDHLSLI RKLYDFAAEE EVLETTIQTI YLKFLLYIDP SVSASELLFT LVSHIKLKGG 120
  121 TYKYVEPLFE DYRDLAVSHF DDLQAKENLT TNIGKDTIFD LLASIIFDFK DIDITPDFLI 180
  181 EVAKSKQD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [617-753]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPVYTSKAVT FLTQLLSGEP SNGYTYENAT ALLSYPNFTI STWKSINVNN LFKSVMEKFS  60
   61 LDKFKFFAEI YQKTYECRFD TIELNFNDLL SLYEMVKKSA NQCSRESFKV KDSAYSSYFE 120
  121 LLNTFLKTYA LNRDSSE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [754-919]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNDDELHILL RLVDENINKD NGNYLGNLAV CKLLYFIIDS YIHCSTSVSD DDIFIVKFIF  60
   61 EKFSFIWECI NSERLVLKER DLHLMLIKGL FHPVILYFGS NQYIDTLTSK LEEHAQTIIS 120
  121 LSYSRRSLLP LLGSQLRVFM KFYGKLLRED VNYWWLINII VGVFKQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7

Region A:
Residues: [920-1127]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQMDVNLYKL KPVISSLFDH KLNNYYIKGD ELYEKVYGPD EILARVSIID SILYANDQLK  60
   61 IRLIEKVTEK TNALYAIKRT DGAEALQRLL QWQLLLLSLL TTNEKKLSET SMIRILKSIE 120
  121 DESSPLVRVY KEWFISSKVV DYYKTGNPKF AEDYLFSLLE DHSKPVFVVS AEKICFMVLK 180
  181 DLRNDEKKYG FTQLLDRFIC TLVPNAAS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8

Region A:
Residues: [1128-1206]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKPLVRHFSN SLIISLWPTF KAYLSDHTLR NIIENLYSNA KKTQIFGQYR AGDANIWDLK  60
   61 GDRKLTNMFG GVLKKVTDH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9

Region A:
Residues: [1207-1436]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DCPYISESVF EKYLQEKDIV PIGTDERSLW LDKRDTNTES VNNANISCDT SPLQTKSGAW  60
   61 ETVLDLDNKK SNDVVTRSEL IVVSSLVDKP PNLGGICRLC DVLGVGLLTV QDIKVKNHPQ 120
  121 FKNVAVTADR WMPMEEVALD EIASFMKEKK KEGYTLIGLE QTDKSVKLDN NFQFPKKSLI 180
  181 LLGTEAFGIP GTLLSELDLC LEIQQFGVIR SMNIQTATAV IVHSYTVQHM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.69897
Match:	2ha8A
Description:	No description for 2ha8A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits