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View Structure Prediction Details

Protein: RPN6
Organism: Saccharomyces cerevisiae
Length: 434 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPN6.

Description E-value Query
Range
Subject
Range
CSN2_RAT - COP9 signalosome complex subunit 2 OS=Rattus norvegicus GN=Cops2 PE=1 SV=1
gi|57108185 - gi|57108185|ref|XP_535470.1| PREDICTED: similar to COP9 (constitutive photomorphogenic) homolog, sub...
gi|190689395, gi... - gi|190690757|gb|ACE87153.1| COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) prote...
tr|M3XER3|M3XER3... - COP9 signalosome subunit 2 OS=Felis catus GN=COPS2 PE=4 SV=1
CSN2_MOUSE - COP9 signalosome complex subunit 2 OS=Mus musculus GN=Cops2 PE=1 SV=1
gi|109081050 - gi|109081050|ref|XP_001113656.1| PREDICTED: similar to COP9 (constitutive photomorphogenic) homolog,...
COPS2 - COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)
gi|157427726, gi... - gi|157427726|ref|NP_001098771.1| COP9 constitutive photomorphogenic homolog subunit 2 [Sus scrofa], ...
gi|114656917 - gi|114656917|ref|XP_510388.2| PREDICTED: similar to COP9 complex subunit 2 isoform 2 [Pan troglodyte...
gi|149691961 - gi|149691961|ref|XP_001502205.1| PREDICTED: similar to COP9 complex subunit 2 isoform 1 [Equus cabal...
gi|224062509 - gi|224062509|ref|XP_002198608.1| PREDICTED: COP9 constitutive photomorphogenic homolog subunit 2 [Ta...
4.0E-77 [10..431] [19..443]
gi|18606281 - gi|18606281|gb|AAH23096.1| Cops2 protein [Mus musculus]
7.0E-77 [10..431] [16..440]
gi|194190744, gi... - gi|195577757|ref|XP_002078735.1| GD22368 [Drosophila simulans], gi|194190744|gb|EDX04320.1| GD22368 ...
FBpp0308633, FBp... - The gene alien is referred to in FlyBase by the symbol Dmel\alien (CG9556, FBgn0013746). It is a pro...
gi|195473219, gi... - gi|195473219|ref|XP_002088893.1| GE10643 [Drosophila yakuba], gi|194174994|gb|EDW88605.1| GE10643 [D...
gi|194130177, gi... - gi|195339379|ref|XP_002036297.1| GM12583 [Drosophila sechellia], gi|194130177|gb|EDW52220.1| GM12583...
gi|194858832, gi... - gi|194858832|ref|XP_001969266.1| GG24040 [Drosophila erecta], gi|190661133|gb|EDV58325.1| GG24040 [D...
6.0E-74 [10..431] [19..444]
gi|190405102 - gi|190405102|gb|EDV08369.1| 26S proteasome regulatory subunit RPN6 [Saccharomyces cerevisiae RM11-1a...
gi|151941906 - gi|151941906|gb|EDN60262.1| proteasome regulatory particle subunit [Saccharomyces cerevisiae YJM789]
RPN6 - Essential, non-ATPase regulatory subunit of the 26S proteasome lid required for the assembly and act...
gi|207347002 - gi|207347002|gb|EDZ73323.1| YDL097Cp-like protein [Saccharomyces cerevisiae AWRI1631]
RPN6_YEAST - 26S proteasome regulatory subunit RPN6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=R...
5.0E-73 [1..434] [1..434]
CSN2_ARATH - COP9 signalosome complex subunit 2 OS=Arabidopsis thaliana GN=CSN2 PE=1 SV=1
4.0E-69 [9..429] [12..437]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-67 [4..431] [6..420]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPGSKLEE ARRLVNEKQY NEAEQVYLSL LDKDSSQSSA AAGASVDDKR RNEQETSILE  60
   61 LGQLYVTMGA KDKLREFIPH STEYMMQFAK SKTVKVLKTL IEKFEQVPDS LDDQIFVCEK 120
  121 SIEFAKREKR VFLKHSLSIK L

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.43
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [142-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATLHYQKKQY KDSLALINDL LREFKKLDDK PSLVDVHLLE SKVYHKLRNL AKSKASLTAA  60
   61 RTAANSIYCP TQTVAELDLM SGILHCEDKD YKTAFSYFFE SFESYHNLTT HNSYEKACQV 120
  121 LK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.43
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [264-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YMLLSKIMLN LIDDVKNILN AKYTKETYQS RGIDAMKAVA EAYNNRSLLD FNTALKQYEK  60
   61 ELMGDELTRS HFNALYDTLL ESNLCKIIEP FECVEISHIS KIIGLDTQQV EGKLSQMILD 120
  121 KIFYGVLDQG NGWLYVYETP NQDATYDSAL ELVGQLNKVV DQLFEKASVL Y

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.43
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

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Created and Maintained by: Michael Riffle