YRC Public Data Repository - Protein Structure Prediction

Protein:	RAM1
Organism:	Saccharomyces cerevisiae
Length:	431 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAM1.

Description	E-value	Query Range	Subject Range
RAM1 - Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone a... FNTB_YEAST - Protein farnesyltransferase subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...	0.0	[1..431]	[1..431]
FNTB_BOVIN - Protein farnesyltransferase subunit beta OS=Bos taurus GN=FNTB PE=2 SV=1	0.0	[15..424]	[18..416]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-99	[15..424]	[18..416]
ENSPTRT00000011804 - null gi\|123982626, gi... - gi\|123997291\|gb\|ABM86247.1\| farnesyltransferase, CAAX box, beta [synthetic construct], gi\|123982626\|... FNTB - farnesyltransferase, CAAX box, beta	2.0E-99	[15..424]	[18..416]
gi\|56553908 - gi\|56553908\|pdb\|1TN8\|B Chain B, Protein Farnesyltransferase Complexed With A H-Ras Peptide Substrate... FNTB_RAT - Protein farnesyltransferase subunit beta OS=Rattus norvegicus GN=Fntb PE=1 SV=1	3.0E-99	[15..424]	[18..416]
PGTB_MOUSE, PGTB... - Geranylgeranyl transferase type-2 subunit beta - Mus musculus (Mouse), Geranylgeranyl transferase ty...	4.0E-93	[71..419]	[18..331]

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Predicted Domain #1

Region A:
Residues: [1-342]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQRVGRSIA RAKFINTALL GRKRPVMERV VDIAHVDSSK AIQPLMKELE TDTTEARYKV  60
   61 LQSVLEIYDD EKNIEPALTK EFHKMYLDVA FEISLPPQMT ALDASQPWML YWIANSLKVM 120
  121 DRDWLSDDTK RKIVDKLFTI SPSGGPFGGG PGQLSHLAST YAAINALSLC DNIDGCWDRI 180
  181 DRKGIYQWLI SLKEPNGGFK TCLEVGEVDT RGIYCALSIA TLLNILTEEL TEGVLNYLKN 240
  241 CQNYEGGFGS CPHVDEAHGG YTFCATASLA ILRSMDQINV EKLLEWSSAR QLQEERGFCG 300
  301 RSNKLVDGCY SFWVGGSAAI LEAFGYGQCF NKHALRDYIL YC

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [343-431]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CQEKEQPGLR DKPGAHSDFY HTNYCLLGLA VAESSYSCTP NDSPHNIKCT PDRLIGSSKL  60
   61 TDVNPVYGLP IENVRKIIHY FKSNLSSPS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits