YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: YDL025C
Organism: Saccharomyces cerevisiae
Length: 620 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDL025C.

Description E-value Query
Range
Subject
Range
YDL025C - Putative protein kinase, potentially phosphorylated by Cdc28p; YDL025C is not an essential gene
RTK1_YEAST - Probable serine/threonine-protein kinase RTK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
0.0 [1..620] [1..620]
gi|16215467 - gi|16215467|emb|CAC82998.1| calcium-dependent protein kinase 2 [Nicotiana tabacum]
0.0 [200..620] [9..433]
gi|15289758 - gi|15289758|dbj|BAB63463.1| calcium dependent protein kinase [Solanum tuberosum]
0.0 [200..620] [9..430]
gi|16215475 - gi|16215475|emb|CAC83000.1| calcium-dependent protein kinase 2 [Nicotiana benthamiana]
0.0 [208..620] [17..433]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [200..620] [9..426]
CDPKH_ARATH - Calcium-dependent protein kinase 17 OS=Arabidopsis thaliana GN=CPK17 PE=2 SV=1
0.0 [252..620] [23..389]

Back

Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKETPLHSS SSTSLSSLFR PTKLKNLSAK IFNGGGNQSY SKTDDVSRSS SRSSKKNTDS  60
   61 DQEDQIKYNK PNDRRSTIGK SPQGNGAL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.299 a.118.8 TPR-like
View Download 0.323 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.429 a.29.4 RecG, N-terminal domain

Predicted Domain #2
Region A:
Residues: [89-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKESHVVASS TLTGISPTSA KKAPIDYSPS RPLPNNHNPV RTGHTVPHLP HSIHNPINYI  60
   61 HQGSKDAFHH PHPVRSTAHS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1f3mA_
Description: pak1 autoregulatory domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [169-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NISTVSSAKS DTPSSNLSYQ AHMHPVEILQ KQIEDKHFMD SQASTPGSVE LQHNSSSGSD  60
   61 DTSSRKKKSL RLTRFFKKIH NDYHDNHHHH HHHNRGSTPT KPKLNL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.461 a.4.5 "Winged helix" DNA-binding domain
View Download 0.533 a.26.1 4-helical cytokines
View Download 0.491 a.47.2 t-snare proteins
View Download 0.650 a.7.7 BAG domain
View Download 0.550 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.432 d.52.2 GMP synthetase C-terminal dimerisation domain
View Download 0.412 a.24.3 Cytochromes
View Download 0.412 a.118.1 ARM repeat
View Download 0.409 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.392 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.367 f.14.1 Voltage-gated potassium channels
View Download 0.362 d.52.4 YhbC-like, N-terminal domain
View Download 0.355 d.58.5 GlnB-like
View Download 0.344 a.118.1 ARM repeat
View Download 0.339 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.337 f.14.1 Voltage-gated potassium channels
View Download 0.336 f.16.1 Gated mechanosensitive channel
View Download 0.325 d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.317 a.3.1 Cytochrome c
View Download 0.315 d.129.1 TATA-box binding protein-like
View Download 0.310 d.52.6 BolA-like
View Download 0.299 a.61.1 Retroviral matrix proteins
View Download 0.291 a.74.1 Cyclin-like
View Download 0.289 d.222.1 YbaB-like
View Download 0.286 a.3.1 Cytochrome c
View Download 0.284 a.1.1 Globin-like
View Download 0.282 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.280 a.142.1 PTS-regulatory domain, PRD
View Download 0.278 a.7.5 Tubulin chaperone cofactor A
View Download 0.268 a.74.1 Cyclin-like
View Download 0.259 d.58.7 RNA-binding domain, RBD
View Download 0.251 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.244 a.133.1 Phospholipase A2, PLA2
View Download 0.231 a.46.1 Methionine synthase domain
View Download 0.229 a.24.3 Cytochromes
View Download 0.225 d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.221 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.203 d.212.1 TolA/TonB C-terminal domain

Predicted Domain #4
Region A:
Residues: [275-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTNENIVESN GKALYETDNP VELLEKYGIP GRKLGEGASG SVSVVERTDG KLFACKMFRK  60
   61 PHLNNEGTNQ SQLANYSKKV TT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [373-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDMLTEGDTY LLVME

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 342.70927
Match: 1ia8A_
Description: Cell cycle checkpoint kinase chk1
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [357-372]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFCIGSTLHH ENIVET

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [388-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YAPYDFFNL

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [411-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKQLCHGVNY LHSMGLAHRD LKLDNCVVTK DGILKLIDFG SAVVFQYPYE DTIV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 342.70927
Match: 1ia8A_
Description: Cell cycle checkpoint kinase chk1
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [397-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VMSNLMTQDE VNCY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [465-620]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSHGIVGSDP YLAPELLKQT SYDPRVADVW SIAIIFYCMV LKRFPWKAPK KSFNSFRLFT  60
   61 EEPEDEDDIV RGPNKILRLL PRHSRTIIGR MLALEPKQRV LMNDVVKDDW LVSVPSCEVD 120
  121 PTSGDLVEKP KNHKHHLVTE EELNELTKQH GNKDSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 342.70927
Match: 1ia8A_
Description: Cell cycle checkpoint kinase chk1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle