YRC Public Data Repository - Protein Structure Prediction

Protein:	GPD1
Organism:	Saccharomyces cerevisiae
Length:	391 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPD1.

Description	E-value	Query Range	Subject Range
GPD1_SACUV - Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 OS=Saccharomyces uvarum GN=GPD1 PE=3 SV=1 GPD1_YEAST - Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288... gi\|151941971 - gi\|151941971\|gb\|EDN60327.1\| glycerol-3-phosphate dehydrogenase [Saccharomyces cerevisiae YJM789] GPD1 - NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for gr... GPD1_SACBA - Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 OS=Saccharomyces bayanus GN=GPD1 PE=3 SV=1 gi\|436875\|gb\|AAA... - dihydroxyacetone phosphate reductase	0.0	[1..391]	[1..391]
gi\|6572467 - gi\|6572467\|emb\|CAB63118.1\| glycerol-3-phosphate dehydrogenase [Zygosaccharomyces rouxii]	0.0	[1..389]	[1..389]
gi\|577307 - gi\|577307\|dbj\|BAA07648.1\| KIAA0089 [Homo sapiens]	0.0	[7..390]	[38..411]
GPDA_MOUSE - Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic OS=Mus musculus GN=Gpd1 PE=1 SV=3	0.0	[35..390]	[4..349]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-99	[35..390]	[3..348]

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Predicted Domain #1

Region A:
Residues: [1-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAAADRLNL TSGHLNAGRK RSSSSVSLKA AEKPFKVTVI GSGNWGTTIA KVVAENCKGY  60
   61 PEVFAPIVQM WVFEEEINGE KLTEIINTRH QNVKYLPGIT LPDNLVANPD LIDSVKDVDI 120
  121 IVFNIPHQFL PRICSQLKGH VDSHVRAISC LKGFEVGAKG VQLLSSYITE ELGIQCGALS 180
  181 GANIATEVAQ EHWSETTVAY HIPKDFRGEG KDVDHKVLKA LFHRPYFHVS VIEDVAGISI 240
  241

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [285-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PESREETYYQ ESAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	208.491979
Match:	1evyA_
Description:	Glycerol-3-phosphate dehydrogenase; Glycerol-3- phosphate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [241-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CGALKNVVAL GCGFVEGLGW GNNASAAIQR VGLGEIIRFG QMFF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [299-391]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VADLITTCAG GRNVKVARLM ATSGKDAWEC EKELLNGQSA QGLITCKEVH EWLETCGSVE  60
   61 DFPLFEAVYQ IVYNNYPMKN LPDMIEELDL HED

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	208.491979
Match:	1evyA_
Description:	Glycerol-3-phosphate dehydrogenase; Glycerol-3- phosphate dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits