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View Structure Prediction Details

Protein: ARE1
Organism: Saccharomyces cerevisiae
Length: 610 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARE1.

Description E-value Query
Range
Subject
Range
ARE1_YEAST - Sterol O-acyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARE1 PE=1 SV=...
gi|190406477 - gi|190406477|gb|EDV09744.1| acyl-CoA cholesterol acyltransferase [Saccharomyces cerevisiae RM11-1a]
ARE1 - Acyl-CoA:sterol acyltransferase, isozyme of Are2p; endoplasmic reticulum enzyme that contributes the...
0.0 [1..610] [1..610]
gi|7576941 - gi|7576941|gb|AAF64065.1|AF251794_1 putative diacylglycerol acyltransferase [Brassica napus]
0.0 [158..610] [85..493]
DGAT1_ARATH - Diacylglycerol O-acyltransferase 1 OS=Arabidopsis thaliana GN=DGAT1 PE=1 SV=2
0.0 [159..610] [105..512]
gi|6625653 - gi|6625653|gb|AAF19345.1|AF129003_1 diacylglycerol acylCoA acyltransferase [Nicotiana tabacum]
0.0 [145..609] [99..523]
gi|10803053 - gi|10803053|gb|AAG23696.1|AF298815_1 diacylglycerol acyltransferase [Perilla frutescens]
0.0 [145..610] [97..526]
gi|18698659, gi|... - gi|18698659|gb|AAL78366.1|AF468650_1 acyl coenzyme A:diacylglycerol acyltransferase [Drosophila mela...
0.0 [141..609] [97..548]
DGAT1_MOUSE - Diacylglycerol O-acyltransferase 1 OS=Mus musculus GN=Dgat1 PE=1 SV=1
0.0 [158..608] [48..484]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTETKDLLQD EEFLKIRRLN SAEANKRHSV TYDNVILPQE SMEVSPRSST TSLVEPVEST  60
   61 EGVESTEAER VAGKQEQEEE YPVDAHMQKY LSHLKSKSRS RFHRKDASKY VSFFGDVSFD 120
  121 PRPTLLDSAI N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.545 a.118.8 TPR-like
View Download 0.436 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.460 a.79.1 Antitermination factor NusB
View Download 0.376 a.69.2 Ypt/Rab-GAP domain of gyp1p
View Download 0.545 a.118.8 TPR-like
View Download 0.485 a.118.8 TPR-like
View Download 0.460 a.79.1 Antitermination factor NusB
View Download 0.436 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.422 d.92.2 beta-N-acetylhexosaminidase-like domain
View Download 0.422 d.92.2 beta-N-acetylhexosaminidase-like domain
View Download 0.356 a.4.1 Homeodomain-like
View Download 0.340 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.330 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.314 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.248 a.152.1 Antioxidant defence protein AhpD
View Download 0.241 c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.223 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.223 d.26.1 FKBP-like

Predicted Domain #2
Region A:
Residues: [132-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPFQTTFKGP VLEKQLKNLQ LTKTKTKATV KTTVKTTEKT DKADAPPGEK LESNFSGIYV  60
   61 FAWMFLGWIA IRCCTDYYAS YGSAWNKLEI VQYMTTDLFT IAMLDLAMFL CTFFVVFVHW 120
  121 LVKKRIINWK WTGFVAVSIF ELAFIPVTFP IYVYYFDFNW VTRIFLFLHS VVFVMKSHSF 180
  181 AFYN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [316-367]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYLWDIKQEL EYSSKQLQKY KESLSPETRE ILQKSCDFCL FELNYQTKDN DF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.397 a.4.5 "Winged helix" DNA-binding domain
View Download 0.455 a.65.1 Annexin
View Download 0.764 a.144.1 PABC (PABP) domain
View Download 0.404 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.780 a.144.2 Ribosomal protein L20
View Download 0.356 a.60.2 RuvA domain 2-like
View Download 0.318 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.313 a.157.1 Skp1 dimerisation domain-like
View Download 0.288 a.4.1 Homeodomain-like
View Download 0.280 a.4.1 Homeodomain-like
View Download 0.279 g.58.1 Pheromone ER-23
View Download 0.275 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.273 a.6.1 Putative DNA-binding domain
View Download 0.230 a.5.2 UBA-like
View Download 0.224 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.212 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.210 a.4.1 Homeodomain-like
View Download 0.203 a.144.1 PABC (PABP) domain

Predicted Domain #4
Region A:
Residues: [368-610]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNNISCSNFF MFCLFPVLVY QINYPRTSRI RWRYVLEKVC AIIGTIFLMM VTAQFFMHPV  60
   61 AMRCIQFHNT PTFGGWIPAT QEWFHLLFDM IPGFTVLYML TFYMIWDALL NCVAELTRFA 120
  121 DRYFYGDWWN CVSFEEFSRI WNVPVHKFLL RHVYHSSMGA LHLSKSQATL FTFFLSAVFH 180
  181 EMAMFAIFRR VRGYLFMFQL SQFVWTALSN TKFLRARPQL SNVVFSFGVC SGPSIIMTLY 240
  241 LTL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 129.200659
Match: PF01800
Description: No description for PF01800 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [499-610]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSFEEFSRIW NVPVHKFLLR HVYHSSMGAL HLSKSQATLF TFFLSAVFHE MAMFAIFRRV  60
   61 RGYLFMFQLS QFVWTALSNT KFLRARPQLS NVVFSFGVCS GPSIIMTLYL TL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle