| Protein: | NPP1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 742 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NPP1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..742] | [1..742] |
|
|
4.0E-89 | [156..616] | [180..594] |
|
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2.0E-88 | [144..616] | [132..560] |
|
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2.0E-88 | [156..616] | [180..594] |
|
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3.0E-88 | [156..616] | [180..594] |
|
Region A: Residues: [1-136] |
1 11 21 31 41 51
| | | | | |
1 MELQNDLESL DNELNDFSED PFRDDFITDE DAVRSGWRSA WTRMKYWFYK NRLKWTNNPI 60
61 VIGDAKDSRD GSNFRRGIPL YELDANGQPI DTELVDENEL SFGTGFHSKV PFKIIFRTLF 120
121 GSLVFAIFLI LMINIA
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.326 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.326 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.201 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.201 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
|
Region A: Residues: [137-493] |
1 11 21 31 41 51
| | | | | |
1 KPHHSTRVLS HFGSPEFDPY VKYFNGTHEF FPLTIVISLD GFHPSLISKR NTPFLHDLYE 60
61 LKYDGGMNIT STPFMVPSFP TETFPNHWTL VTGQYPIHHG IVSNVFWDPD LNEEFHPGVL 120
121 DPRIWNNNDT EPIWQTVQSA FDGDIPFKAA THMWPGSDVN YTKYNEEKLQ PEHKNPIARE 180
181 RTPFYFDEFN AKEPLSQKLS KIIEYVDMST LNERPQLILG YVPNVDAFGH KHGYPSESEY 240
241 YYEDFTETLG EVDTFLKQLV ESLQERNLTS FTNLVIVSDH GMSDIVVPSN VIIWEDLLDE 300
301 KLRKDYVSHA YLEGPMMAIS LKDSGNINEV YHNLKTSIDE DKYTVYVNGN FPKEWNF
|
| Detection Method: | |
| Confidence: | 38.221849 |
| Match: | 1e1zP_ |
| Description: | Arylsulfatase A |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [494-550] |
1 11 21 31 41 51
| | | | | |
1 NDGKNHHMAS IWIVPEPGYA VMKKEQLKKV AKGDHKDKNE DNVFTIGSHG YDNNAID
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.558 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.551 | d.74.2 | C-terminal domain of arginine repressor |
| View | Download | 0.545 | d.58.17 | Metal-binding domain |
| View | Download | 0.512 | a.24.3 | Cytochromes |
| View | Download | 0.499 | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.497 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.493 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.490 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.488 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.476 | d.80.1 | Tautomerase/MIF |
| View | Download | 0.474 | g.15.1 | Ovomucoid/PCI-1 like inhibitors |
| View | Download | 0.468 | d.58.38 | Urease metallochaperone UreE, C-terminal domain |
| View | Download | 0.408 | d.64.1 | eIF1-like |
| View | Download | 0.382 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.351 | d.58.10 | Acylphosphatase-like |
| View | Download | 0.278 | a.4.1 | Homeodomain-like |
| View | Download | 0.269 | d.58.49 | YajQ-like |
| View | Download | 0.250 | d.58.25 | Killer toxin KP6 alpha-subunit |
| View | Download | 0.232 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.220 | d.58.48 | MTH1187-like |
|
Region A: Residues: [551-636] |
1 11 21 31 41 51
| | | | | |
1 MRSVFIGMGP YFPQGYIEPF QNTEIYNLLC DICGVAEKDR NSNDGTGMLM NQLREPQSSE 60
61 EVEIEDDFDY LVSKFGEFST YNIIWG
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.693 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.603 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.384 | N/A | N/A | c.9.1 | Barstar (barnase inhibitor) |
| View | Download | 0.380 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.365 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.348 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.310 | N/A | N/A | a.101.1 | Uteroglobin-like |
| View | Download | 0.298 | N/A | N/A | a.28.1 | ACP-like |
| View | Download | 0.293 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.292 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.285 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.270 | N/A | N/A | a.158.1 | F-box domain |
| View | Download | 0.244 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.243 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.230 | N/A | N/A | d.58.48 | MTH1187-like |
| View | Download | 0.229 | N/A | N/A | d.80.1 | Tautomerase/MIF |
| View | Download | 0.222 | N/A | N/A | a.4.1 | Homeodomain-like |
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Region A: Residues: [637-742] |
1 11 21 31 41 51
| | | | | |
1 GYPEETEQDN VDNDNDDNDD GNTDEIAAMP SSSLTIKLEM TTSIPSATET LLGETSPSSR 60
61 SSSSSSIQAS ATASTVGDWL QDIINDAKDL IDDIIDSIDD LVDSDT
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.558 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.512 | a.24.3 | Cytochromes |
| View | Download | 0.497 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.493 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.488 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.456 | a.63.1 | Apolipophorin-III |
| View | Download | 0.425 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.410 | b.34.8 | Fumarylacetoacetate hydrolase, FAH, N-terminal domain |
| View | Download | 0.401 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.386 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.349 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.349 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.319 | a.29.2 | Bromodomain |
| View | Download | 0.312 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.286 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.271 | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.269 | a.24.3 | Cytochromes |
| View | Download | 0.266 | c.54.1 | IIA domain of mannose transporter, IIA-Man |
| View | Download | 0.263 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.261 | a.46.1 | Methionine synthase domain |
| View | Download | 0.255 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.227 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.222 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.216 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.214 | a.39.2 | Insect pheromon/odorant-binding proteins |
| View | Download | 0.211 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.205 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.204 | a.90.1 | Transcription factor STAT-4 N-domain |
