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View Structure Prediction Details

Protein: EMC1
Organism: Saccharomyces cerevisiae
Length: 760 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EMC1.

Description E-value Query
Range
Subject
Range
EMC1 - Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant ...
EMC1_YEAST - ER membrane protein complex subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EM...
0.0 [1..760] [1..760]
FBpp0308770, CG2... - This gene is referred to in FlyBase by the symbol Dmel\CG2943 (CG2943, FBgn0037530). It is a protein...
0.0 [168..757] [312..914]
CE27186 - status:Confirmed UniProt:O44825 protein_id:AAK31541.1
0.0 [145..757] [313..945]
EMC1_SCHPO - ER membrane protein complex subunit 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=emc1...
SPAC25H1.07 - DUF1620 family protein
0.0 [157..757] [312..883]
gi|6473377 - gi|6473377|dbj|BAA87126.1| Hypothetical protein [Schizosaccharomyces pombe]
8.0E-34 [157..310] [48..181]

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Predicted Domain #1
Region A:
Residues: [1-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKITCTDLVY VFILLFLNTS CVQAVFSDDA FITDWQLANL GPWEKVIPDS RDRNRVLILS  60
   61 NPTETSCLVS SFNVSSGQIL FRNVLPFTID EIQLDSNDHN AMVCVNSSSN HWQKYDLHDW 120
  121 FLLEEGVDNA PSTTILPQSS YLNDQVSIKN NELHILDEQS KLAEWKLELP QGFNKVEYFH 180
  181 REDPLALVLN VNDTQYMGFS A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 1.49721450547449 bayes_pls_golite062009
catalytic activity 1.30141348136874 bayes_pls_golite062009
protein binding 0.418181509648475 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [202-760]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGTELIPVWQ RDEWLTNVVD YAVLDVFDSR DVELNKDMKA ELDSNSLWNA YWLRLTTNWN  60
   61 RLINLLKENQ FSPGRVFTKL LALDAKDTTV SDLKFGFAKI LIVLTHDGFI GGLDMVNKGQ 120
  121 LIWKLDLEID QGVKMFWTDK NHDELVVFSH DGHYLTIEVT KDQPIIKSRS PLSERKTVDS 180
  181 VIRLNEHDHQ YLIKFEDKDH LLFKLNPGKN TDVPIVANNH SSSHIFVTEH DTNGIYGYII 240
  241 ENDTVKQTWK KAVNSKEKMV AYSKRETTNL NTLGITLGDK SVLYKYLYPN LAAYLIANEE 300
  301 HHTITFNLID TITGEILITQ EHKDSPDFRF PMDIVFGEYW VVYSYFSSEP VPEQKLVVVE 360
  361 LYESLTPDER LSNSSDNFSY DPLTGHINKP QFQTKQFIFP EIIKTMSISK TTDDITTKAI 420
  421 VMELENGQIT YIPKLLLNAR GKPAEEMAKD KKKEFMATPY TPVIPINDNF IITHFRNLLP 480
  481 GSDSQLISIP TNLESTSIIC DLGLDVFCTR ITPSGQFDLM SPTFEKGKLL ITIFVLLVIT 540
  541 YFIRPSVSNK KLKSQWLIK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle