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View Structure Prediction Details

Protein: AGP1
Organism: Saccharomyces cerevisiae
Length: 595 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGP1.

Description E-value Query
Range
Subject
Range
AGP1 - Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, gluta...
0.0 [1..593] [1..593]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [21..587] [13..563]
gi|68470470, gi|... - gi|68470731|ref|XP_720611.1| N-acetylglucosamine-inducible general amino acid permease [Candida albi...
gi|18568390 - gi|18568390|gb|AAL76065.1| Gap1 protein [Candida albicans]
gi|238882678 - gi|238882678|gb|EEQ46316.1| general amino-acid permease GAP1 [Candida albicans WO-1]
0.0 [33..590] [6..539]
gi|15054460 - gi|15054460|dbj|BAB62308.1| branched-chain amino acid permease [Saccharomyces pastorianus]
gi|15054462 - gi|15054462|dbj|BAB62309.1| branched-chain amino acid permease [Saccharomyces bayanus]
0.0 [21..587] [13..563]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSKSLYEL KDLKNSSTEI HATGQDNEIE YFETGSNDRP SSQPHLGYEQ HNTSAVRRFF  60
   61 DSFKRADQGP QDEVEATQMN DLTSAIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.401 a.74.1 Cyclin-like
View Download 0.417 a.2.3 Chaperone J-domain
View Download 0.384 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.397 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.514 a.20.1 PGBD-like
View Download 0.376 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.354 d.58.49 YajQ-like
View Download 0.335 a.29.2 Bromodomain
View Download 0.324 a.74.1 Cyclin-like
View Download 0.320 a.39.2 Insect pheromon/odorant-binding proteins
View Download 0.316 a.6.1 Putative DNA-binding domain
View Download 0.309 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.281 a.2.5 Prefoldin
View Download 0.274 a.40.1 Calponin-homology domain, CH-domain
View Download 0.271 a.64.1 Saposin
View Download 0.266 a.138.1 Multiheme cytochromes
View Download 0.243 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.233 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.233 a.39.1 EF-hand
View Download 0.222 a.24.15 FAD-dependent thiol oxidase
View Download 0.211 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.211 a.118.1 ARM repeat

Predicted functions:

Term Confidence Notes
binding 2.16072293434243 bayes_pls_golite062009
cytoskeletal protein binding 1.56123529621268 bayes_pls_golite062009
protein binding 1.36724461365736 bayes_pls_golite062009
tubulin binding 1.27811933320559 bayes_pls_golite062009
signal transducer activity 0.941563416769786 bayes_pls_golite062009
molecular transducer activity 0.941563416769786 bayes_pls_golite062009
microtubule binding 0.433976380647151 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [88-595]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSSRQAQELE KNESSDNIGA NTGHKSDSLK KTIQPRHVLM IALGTGIGTG LLVGNGTALV  60
   61 HAGPAGLLIG YAIMGSILYC IIQACGEMAL VYSNLTGGYN AYPSFLVDDG FGFAVAWVYC 120
  121 LQWLCVCPLE LVTASMTIKY WTTSVNPDVF VIIFYVLVIT INIFGARGYA EAEFFFNCCK 180
  181 ILMMTGFFIL GIIIDVGGAG NDGFIGGKYW HDPGAFNGKH AIDRFKGVAA TLVTAAFAFG 240
  241 GSEFIAITTA EQSNPRKAIP GAAKQMIYRI LFLFLATIIL LGFLVPYNSD QLLGSTGGGT 300
  301 KASPYVIAVA SHGVRVVPHF INAVILLSVL SMANSSFYSS ARLFLTLSEQ GYAPKVFSYI 360
  361 DRAGRPLIAM GVSALFAVIA FCAASPKEEQ VFTWLLAISG LSQLFTWTAI CLSHLRFRRA 420
  421 MKVQGRSLGE LGFKSQTGVW GSAYACIMMI LILIAQFWVA IAPIGEGKLD AQAFFENYLA 480
  481 MPILIALYVG YKVWHKDWKL FIRETRST

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 202.769551
Match: PF00324
Description: Amino acid permease

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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