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View Structure Prediction Details

Protein: COS2, COS3
Organism: Saccharomyces cerevisiae
Length: 379 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS2, COS3.

Description E-value Query
Range
Subject
Range
COS1 - Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-enc...
COS1_YEAST - Protein COS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COS1 PE=1 SV=1
580.0 [0..1] [375..1]

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Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKENELKNEK SVDVLSFKQL ESQKIVLPQD LFRSSFTWFC YEIYKSLAFR IWMLLWLPLS  60
   61 V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [62-169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WWKLSNNCIY PLIVSLLVLF LGPIFVLVIC GLSRKRSLSK QLIQFCKEIT ENTPSSDPHD  60
   61 WEVVAANLNS YLYENNVWNT KYFFFNAMVC QEAFRTTLLE PFSLKKDK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 52.107905
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [170-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAKVKSFKDS VPYIEEALGV YFTEVEKQWK LFNTEKSWSP VGLEDAKLPK EAYRFKLTWF  60
   61 LKRISNIFML IP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [242-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLNFLCCIYV SRGMCLLLRT LYLGWILFML VQGFQNIRVL IMSMEHKMQF LSTIINEQES  60
   61 GANGWDEIAR KMNRYLFEKK AWKNEEFFFD GIDCEWFFNH FFYRVLSAKK SMWPLPLNVE 120
  121 LWPYIKEAQL SRSEVLLV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 59.267606
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle