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View Structure Prediction Details

Protein: PPS1
Organism: Saccharomyces cerevisiae
Length: 807 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PPS1.

Description E-value Query
Range		 Subject
Range
PPS1_YEAST - Dual specificity protein phosphatase PPS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
PPS1 - Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the...
 0.0 [1..807] [1..807]
gi|85081406 - gi|85081406|ref|XP_956712.1| hypothetical protein NCU03426 [Neurospora crassa OR74A]
gi|32404142, gi|... - gi|32404142|ref|XP_322684.1| hypothetical protein [Neurospora crassa], gi|28917787|gb|EAA27476.1| co...
 2.0E-76 [406..788] [334..666]
DUS1B_XENLA - Dual specificity protein phosphatase 1-B OS=Xenopus laevis GN=dusp1-b PE=2 SV=1
 2.0E-51 [488..785] [80..318]
DUS4_RAT - Dual specificity protein phosphatase 4 OS=Rattus norvegicus GN=Dusp4 PE=2 SV=1
 2.0E-51 [488..785] [102..339]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 4.0E-51 [488..785] [101..338]
gi|1255785 - gi|1255785|gb|AAC50452.1| MKP-2
 5.0E-51 [488..785] [101..338]
DUS4_CHICK - Dual specificity protein phosphatase 4 OS=Gallus gallus GN=DUSP4 PE=2 SV=1
 4.0E-49 [488..785] [85..319]

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Predicted Domain #1
Region A:
Residues: [1-446] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLEVPSITP GELHDLMRLH QDAEWPECKK MFPWAHDISF GQPPDFPHSL AIVKSQSDAN  60
   61 NSALLRNSLE VNDIFQSWKV RTSFHREGDT CETGNDSNGF QYPNNTKELL NLLKFQIRQL 120
  121 ELQVDDVALE NAATYCHNHS ILPFLKVDPR GLSLELKRYS RNKVGSNTTL KRSGQDVWGR 180
  181 RGLFRRFDLQ CAKMIEMVDN IVIYCSRTGG STDMQTESAP ACSHEGNCPN CTTLALLLQI 240
  241 CLMFVQKGYV GSGGSLYKTN LFICTYQNFN TDIPQTLIGT PLLDNEFFKN NTPLNLCSSP 300
  301 SEIVCFNNVD KNMVLCEKLE LNKLTSATRL EETGLICGNT TDWHNYQIIK KNNISLTHRF 360
  361 EENTSIVNLK SLNYDTDNPT TSISQLYNIP NTKEVWKLII KCTSNSQMPS LTKIRTYLDL 420
  421 LLDDDASKSQ EHLHLTFPAS GSIGLG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [447-583] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLNIQSVEIL LNVCYLIFQV SQVQELLTFM YCEDGYTETS LLLTAYIIFH FNIPLQDALL  60
   61 RIHPRPFFLF PSDLQILGHL QPVLREFSPQ NGSNLKLYAN ALKFRDKSFQ LHISSELFSS 120
  121 IFFMKIPLES NFVNLKG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.881 0.191 protein tyrosine/threonine phosphatase activity a.118.8 TPR-like

Predicted Domain #3
Region A:
Residues: [584-807] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLPSRILRHL YLGSLDHAQN PALLKSLGIT HIVSVGEVVS WTLNKDKIAH PVRPHRAITM  60
   61 TNTNEVAGNT TCNKSRNRAD TVVSDKQENG SNVVISENSG FQICQIENLD DNGKDPLFHQ 120
  121 IDKVLDFISN SEATGGKVLV HCMVGVSRSA TVCIAECMRY LQCDLASAYL FVRVRRLNVI 180
  181 IQPNLFFVYE LFKWWKKHYN REKDKTMDWH IICRGIAEVN MKYT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 102.124002
Match: 1ikzA_
Description: Mapk phosphatase

Predicted Domain #4
Region A:
Residues: [379-609] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTTSISQLYN IPNTKEVWKL IIKCTSNSQM PSLTKIRTYL DLLLDDDASK SQEHLHLTFP  60
   61 ASGSIGLGNL NIQSVEILLN VCYLIFQVSQ VQELLTFMYC EDGYTETSLL LTAYIIFHFN 120
  121 IPLQDALLRI HPRPFFLFPS DLQILGHLQP VLREFSPQNG SNLKLYANAL KFRDKSFQLH 180
  181 ISSELFSSIF FMKIPLESNF VNLKGPLPSR ILRHLYLGSL DHAQNPALLK S

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.18
Match: 2hxpA
Description: No description for 2hxpA was found.

Predicted Domain #5
Region A:
Residues: [610-807] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGITHIVSVG EVVSWTLNKD KIAHPVRPHR AITMTNTNEV AGNTTCNKSR NRADTVVSDK  60
   61 QENGSNVVIS ENSGFQICQI ENLDDNGKDP LFHQIDKVLD FISNSEATGG KVLVHCMVGV 120
  121 SRSATVCIAE CMRYLQCDLA SAYLFVRVRR LNVIIQPNLF FVYELFKWWK KHYNREKDKT 180
  181 MDWHIICRGI AEVNMKYT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.522879
Match: 2esbA
Description: No description for 2esbA was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle