| Protein: | ROT2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 954 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ROT2.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..954] | [1..954] |
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0.0 | [7..952] | [18..940] |
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0.0 | [7..952] | [19..941] |
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0.0 | [7..952] | [19..963] |
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0.0 | [4..952] | [4..918] |
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0.0 | [1..952] | [6..940] |
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0.0 | [3..953] | [5..917] |
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Region A: Residues: [1-82] |
1 11 21 31 41 51
| | | | | |
1 MVLLKWLVCQ LVFFTAFSHA FTDYLLKKCA QSGFCHRNRV YAENIAKSHH CYYKVDAESI 60
61 AHDPLENVLH ATIIKTIPRL EG
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.339 | 0.026 | alpha-glucosidase activity | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.355 | 0.026 | alpha-glucosidase activity | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.548 | 0.026 | alpha-glucosidase activity | a.65.1 | Annexin |
| View | Download | 0.379 | 0.026 | alpha-glucosidase activity | a.83.1 | Guanido kinase N-terminal domain |
| View | Download | 0.933 | 0.026 | alpha-glucosidase activity | d.45.1 | ClpS-like |
| View | Download | 0.538 | 0.026 | alpha-glucosidase activity | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.721 | 0.026 | alpha-glucosidase activity | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.933 | 0.026 | alpha-glucosidase activity | d.45.1 | ClpS-like |
| View | Download | 0.721 | 0.026 | alpha-glucosidase activity | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.548 | 0.026 | alpha-glucosidase activity | a.65.1 | Annexin |
| View | Download | 0.538 | 0.026 | alpha-glucosidase activity | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.533 | 0.026 | alpha-glucosidase activity | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.533 | 0.026 | alpha-glucosidase activity | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.492 | 0.026 | alpha-glucosidase activity | a.77.1 | DEATH domain |
| View | Download | 0.451 | 0.026 | alpha-glucosidase activity | a.112.1 | Description not found. |
| View | Download | 0.433 | 0.026 | alpha-glucosidase activity | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.431 | 0.026 | alpha-glucosidase activity | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.428 | 0.026 | alpha-glucosidase activity | d.58.17 | Metal-binding domain |
| View | Download | 0.415 | 0.026 | alpha-glucosidase activity | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.371 | 0.026 | alpha-glucosidase activity | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.370 | 0.026 | alpha-glucosidase activity | a.7.1 | Spectrin repeat |
| View | Download | 0.367 | 0.026 | alpha-glucosidase activity | d.58.10 | Acylphosphatase-like |
| View | Download | 0.365 | 0.026 | alpha-glucosidase activity | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.363 | 0.026 | alpha-glucosidase activity | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.362 | 0.026 | alpha-glucosidase activity | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.361 | 0.026 | alpha-glucosidase activity | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.357 | 0.026 | alpha-glucosidase activity | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.353 | 0.026 | alpha-glucosidase activity | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.350 | 0.026 | alpha-glucosidase activity | d.94.1 | HPr-like |
| View | Download | 0.346 | 0.026 | alpha-glucosidase activity | a.4.1 | Homeodomain-like |
| View | Download | 0.341 | 0.026 | alpha-glucosidase activity | a.7.7 | BAG domain |
| View | Download | 0.337 | 0.026 | alpha-glucosidase activity | a.4.1 | Homeodomain-like |
| View | Download | 0.327 | 0.026 | alpha-glucosidase activity | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.326 | 0.026 | alpha-glucosidase activity | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.321 | 0.026 | alpha-glucosidase activity | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.317 | 0.026 | alpha-glucosidase activity | a.4.1 | Homeodomain-like |
| View | Download | 0.313 | 0.026 | alpha-glucosidase activity | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.301 | 0.026 | alpha-glucosidase activity | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.299 | 0.026 | alpha-glucosidase activity | a.7.7 | BAG domain |
| View | Download | 0.297 | 0.026 | alpha-glucosidase activity | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.291 | 0.026 | alpha-glucosidase activity | a.126.1 | Serum albumin-like |
| View | Download | 0.288 | 0.026 | alpha-glucosidase activity | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.283 | 0.026 | alpha-glucosidase activity | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.282 | 0.026 | alpha-glucosidase activity | g.53.1 | TAZ domain |
| View | Download | 0.278 | 0.026 | alpha-glucosidase activity | a.47.2 | t-snare proteins |
| View | Download | 0.278 | 0.026 | alpha-glucosidase activity | a.101.1 | Uteroglobin-like |
| View | Download | 0.268 | 0.026 | alpha-glucosidase activity | d.58.40 | D-ribose-5-phosphate isomerase (RpiA), lid domain |
| View | Download | 0.266 | 0.026 | alpha-glucosidase activity | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.262 | 0.026 | alpha-glucosidase activity | a.46.1 | Methionine synthase domain |
| View | Download | 0.261 | 0.026 | alpha-glucosidase activity | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.261 | 0.026 | alpha-glucosidase activity | a.64.1 | Saposin |
| View | Download | 0.258 | 0.026 | alpha-glucosidase activity | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.258 | 0.026 | alpha-glucosidase activity | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.256 | 0.026 | alpha-glucosidase activity | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.255 | 0.026 | alpha-glucosidase activity | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
| View | Download | 0.251 | 0.026 | alpha-glucosidase activity | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.246 | 0.026 | alpha-glucosidase activity | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.244 | 0.026 | alpha-glucosidase activity | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.243 | 0.026 | alpha-glucosidase activity | a.77.1 | DEATH domain |
| View | Download | 0.243 | 0.026 | alpha-glucosidase activity | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.242 | 0.026 | alpha-glucosidase activity | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.240 | 0.026 | alpha-glucosidase activity | a.24.11 | Bacterial GAP domain |
| View | Download | 0.239 | 0.026 | alpha-glucosidase activity | g.53.1 | TAZ domain |
| View | Download | 0.239 | 0.026 | alpha-glucosidase activity | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.237 | 0.026 | alpha-glucosidase activity | a.118.14 | FliG |
| View | Download | 0.236 | 0.026 | alpha-glucosidase activity | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.232 | 0.026 | alpha-glucosidase activity | a.112.1 | Description not found. |
| View | Download | 0.231 | 0.026 | alpha-glucosidase activity | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.231 | 0.026 | alpha-glucosidase activity | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.230 | 0.026 | alpha-glucosidase activity | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.227 | 0.026 | alpha-glucosidase activity | a.64.1 | Saposin |
| View | Download | 0.223 | 0.026 | alpha-glucosidase activity | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.222 | 0.026 | alpha-glucosidase activity | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.222 | 0.026 | alpha-glucosidase activity | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.221 | 0.026 | alpha-glucosidase activity | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.219 | 0.026 | alpha-glucosidase activity | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.219 | 0.026 | alpha-glucosidase activity | d.170.1 | Scavenger receptor cysteine-rich (SRCR) domain |
| View | Download | 0.218 | 0.026 | alpha-glucosidase activity | a.20.1 | PGBD-like |
| View | Download | 0.217 | 0.026 | alpha-glucosidase activity | d.74.3 | RBP11-like subunits of RNA polymerase |
| View | Download | 0.214 | 0.026 | alpha-glucosidase activity | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.213 | 0.026 | alpha-glucosidase activity | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.212 | 0.026 | alpha-glucosidase activity | a.101.1 | Uteroglobin-like |
| View | Download | 0.209 | 0.026 | alpha-glucosidase activity | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.206 | 0.026 | alpha-glucosidase activity | d.39.1 | Dynein light chain 8 (DLC8) |
| View | Download | 0.205 | 0.026 | alpha-glucosidase activity | d.120.1 | Cytochrome b5 |
| View | Download | 0.205 | 0.026 | alpha-glucosidase activity | a.126.1 | Serum albumin-like |
| View | Download | 0.204 | 0.026 | alpha-glucosidase activity | a.12.1 | Kix domain of CBP (creb binding protein) |
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Region A: Residues: [83-390] |
1 11 21 31 41 51
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1 DDIAVQFPFS LSFLQDHSVR FTINEKERMP TNSSGLLISS QRFNETWKYA FDKKFQEEAN 60
61 RTSIPQFHFL KQKQTVNSFW SKISSFLSLS NSTADTFHLR NGDVSVEIFA EPFQLKVYWQ 120
121 NALKLIVNEQ NFLNIEHHRT KQENFAHVLP EETTFNMFKD NFLYSKHDSM PLGPESVALD 180
181 FSFMGSTNVY GIPEHATSLR LMDTSGGKEP YRLFNVDVFE YNIGTSQPMY GSIPFMFSSS 240
241 STSIFWVNAA DTWVDIKYDT SKNKTMTHWI SENGVIDVVM SLGPDIPTII DKFTDLTGRP 300
301 FLPPISSI
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
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Region A: Residues: [391-586] |
1 11 21 31 41 51
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1 GYHQCRWNYN DEMDVLTVDS QMDAHMIPYD FIWLDLEYTN DKKYFTWKQH SFPNPKRLLS 60
61 KLKKLGRNLV VLIDPHLKKD YEISDRVINE NVAVKDHNGN DYVGHCWPGN SIWIDTISKY 120
121 GQKIWKSFFE RFMDLPADLT NLFIWNDMNE PSIFDGPETT APKDLIHDNY IEERSVHNIY 180
181 GLSVHEATYD AIKSIY
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| Detection Method: | |
| Confidence: | 2.154902 |
| Match: | 2taaA_ |
| Description: | Fungal alpha-amylase; Fungal alpha-amylases |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [587-814] |
1 11 21 31 41 51
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1 SPSDKRPFLL TRAFFAGSQR TAATWTGDNV ANWDYLKISI PMVLSNNIAG MPFIGADIAG 60
61 FAEDPTPELI ARWYQAGLWY PFFRAHAHID TKRREPYLFN EPLKSIVRDI IQLRYFLLPT 120
121 LYTMFHKSSV TGFPIMNPMF IEHPEFAELY HIDNQFYWSN SGLLVKPVTE PGQSETEMVF 180
181 PPGIFYEFAS LHSFINNGTD LIEKNISAPL DKIPLFIEGG HIITMKDK
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
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Region A: Residues: [815-954] |
1 11 21 31 41 51
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1 YRRSSMLMKN DPYVIVIAPD TEGRAVGDLY VDDGETFGYQ RGEYVETQFI FENNTLKNVR 60
61 SHIPENLTGI HHNTLRNTNI EKIIIAKNNL QHNITLKDSI KVKKNGEESS LPTRSSYEND 120
121 NKITILNLSL DITEDWEVIF
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.218 | 0.287 | alpha-glucosidase activity | b.29.1 | Concanavalin A-like lectins/glucanases |
| View | Download | 0.269 | 0.195 | alpha-glucosidase activity | b.60.1 | Lipocalins |
| View | Download | 0.384 | 0.025 | alpha-glucosidase activity | d.85.1 | RNA bacteriophage capsid protein |
| View | Download | 0.214 | 0.006 | alpha-glucosidase activity | b.118.1 | FAS1 domain |
| View | Download | 0.234 | N/A | N/A | c.55.6 | DNA repair protein MutS, domain II |
| View | Download | 0.211 | N/A | N/A | b.60.1 | Lipocalins |
