YRC Public Data Repository - Protein Structure Prediction

Protein:	PCS60
Organism:	Saccharomyces cerevisiae
Length:	543 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PCS60.

Description	E-value	Query Range	Subject Range
gi\|254164004, gi... - gi\|254164004\|ref\|YP_003047112.1\| acetyl-coenzyme A synthetase [Escherichia coli B str. REL606], gi\|2... gi\|83587193, gi\|... - gi\|83587193\|ref\|ZP_00925822.1\| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Escher... gi\|157159006, gi... - gi\|75188792\|ref\|ZP_00702059.1\| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Escher... gi\|194426861, gi... - gi\|75211996\|ref\|ZP_00712051.1\| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Escher... gi\|75238604, gi\|... - gi\|75238604\|ref\|ZP_00722593.1\| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Escher... gi\|75258987, gi\|... - gi\|75258987\|ref\|ZP_00730355.1\| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Escher... EG11448 - acetyl-CoA synthetase / Acetyl CoA synthase, acetate-scavenging enzyme, improves carbon starvation s... gi\|85676821, gi\|... - gi\|89110790\|ref\|AP_004570.1\| bifunctional acetyl-CoA synthetase and propionyl-CoA synthetase [Escher... EG11448 - acetyl-CoA synthetase / Acetyl CoA synthase, acetate-scavenging enzyme, improves carbon starvation s... ACSA_ECOLI - Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme) - Escherich... gi\|218697778, gi... - gi\|218697778\|ref\|YP_002405445.1\| acetyl-CoA synthetase [Escherichia coli 55989], gi\|218354510\|emb\|CA... gi\|218556627, gi... - gi\|218556627\|ref\|YP_002389541.1\| acetyl-CoA synthetase [Escherichia coli IAI1], gi\|218363396\|emb\|CAR... gi\|169756860, gi... - gi\|170021932\|ref\|YP_001726886.1\| acetyl-CoA synthetase [Escherichia coli ATCC 8739], gi\|169756860\|gb... gi\|238903178, gi... - gi\|238903178\|ref\|YP_002928974.1\| acetyl-CoA synthetase [Escherichia coli BW2952], gi\|238859913\|gb\|AC... gi\|251787323, gi... - gi\|251787323\|ref\|YP_003001627.1\| hypothetical protein B21_03901 [Escherichia coli BL21], gi\|24237959... gi\|124527708, gi... - gi\|124527708\|ref\|ZP_01699143.1\| acetate--CoA ligase [Escherichia coli B], gi\|124501151\|gb\|EAY48617.1... gi\|209921555, gi... - gi\|209921555\|ref\|YP_002295639.1\| acetyl-CoA synthetase [Escherichia coli SE11], gi\|209914814\|dbj\|BAG... gi\|254290754, gi... - gi\|254290754\|ref\|YP_003056502.1\| acetyl-coenzyme A synthetase [Escherichia coli BL21(DE3)], gi\|25398... gi\|170083524, gi... - gi\|170083524\|ref\|YP_001732844.1\| acetyl-CoA synthetase [Escherichia coli str. K-12 substr. DH10B], g... gi\|226840180, gi... - gi\|254037074\|ref\|ZP_04871151.1\| acetyl-coenzyme A synthetase [Escherichia sp. 1_1_43], gi\|226840180\|...	0.0	[2..539]	[74..625]
gi\|15804661, gi\|... - gi\|15804661\|ref\|NP_290702.1\| acetyl-CoA synthetase [Escherichia coli O157:H7 EDL933], gi\|12519026\|gb... gi\|217322623, gi... - gi\|217326402\|ref\|ZP_03442486.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. TW14588], gi\|2173... gi\|209751100, gi... - pir\|\|G86100 acetyl-CoA synthetase [imported] - Escherichia coli (strain O157:H7, substrain EDL933),... gi\|209161294, gi... - gi\|209399894\|ref\|YP_002273610.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4115], gi\|2091... gi\|208729342, gi... - gi\|208809541\|ref\|ZP_03251878.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4206], gi\|20872... gi\|195935854 - gi\|195935854\|ref\|ZP_03081236.1\| acetyl-CoA synthetase [Escherichia coli O157:H7 str. EC4024] gi\|208818900, gi... - gi\|208818900\|ref\|ZP_03259220.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4042], gi\|20873... gi\|208812711, gi... - gi\|208812711\|ref\|ZP_03254040.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4045], gi\|20873... gi\|168780486, gi... - gi\|189001801\|gb\|EDU70787.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4076], gi\|168780486... gi\|187769915, gi... - gi\|187769915\|gb\|EDU33759.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4196], gi\|168774431... gi\|189379155, gi... - gi\|189379155\|gb\|EDU97571.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC508], gi\|168798264\|... gi\|189375157, gi... - gi\|189375157\|gb\|EDU93573.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC869], gi\|168784689\|... gi\|189357553, gi... - gi\|189357553\|gb\|EDU75972.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4401], gi\|168755243... gi\|168748079, gi... - gi\|188017377\|gb\|EDU55499.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4113], gi\|168748079... ACSA_ECO57 - Acetyl-coenzyme A synthetase OS=Escherichia coli O157:H7 GN=acs PE=3 SV=1 gi\|168766333, gi... - gi\|189364237\|gb\|EDU82656.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4486], gi\|168766333... gi\|168760922, gi... - gi\|189368558\|gb\|EDU86974.1\| acetate--CoA ligase [Escherichia coli O157:H7 str. EC4501], gi\|168760922... gi\|15834305, gi\|... - gi\|15834305\|ref\|NP_313078.1\| acetyl-CoA synthetase [Escherichia coli O157:H7 str. Sakai], gi\|1336452... gi\|254796089, gi... - gi\|254796089\|ref\|YP_003080926.1\| acetyl-CoA synthetase [Escherichia coli O157:H7 str. TW14359], gi\|2...	0.0	[2..539]	[74..625]
ACSA_SALTI - Acetyl-coenzyme A synthetase OS=Salmonella typhi GN=acs PE=3 SV=1 gi\|213427241 - gi\|213427241\|ref\|ZP_03359991.1\| acetyl-CoA synthetase [Salmonella enterica subsp. enterica serovar T... gi\|213163052 - gi\|213163052\|ref\|ZP_03348762.1\| acetyl-CoA synthetase [Salmonella enterica subsp. enterica serovar T... gi\|16762956 - gi\|16762956\|ref\|NP_458573.1\| acetyl-CoA synthetase [Salmonella enterica subsp. enterica serovar Typh... ACSA_SALTI - Acetyl-coenzyme A synthetase OS=Salmonella typhi GN=acs PE=3 SV=1 gi\|29144443, gi\|... - gi\|29144443\|ref\|NP_807785.1\| acetyl-CoA synthetase [Salmonella enterica subsp. enterica serovar Typh... gi\|214002545 - gi\|214002545\|ref\|ZP_03413280.1\| acetyl-CoA synthetase [Salmonella enterica subsp. enterica serovar T... gi\|213852760 - gi\|213852760\|ref\|ZP_03382292.1\| acetyl-CoA synthetase [Salmonella enterica subsp. enterica serovar T...	0.0	[2..539]	[74..625]
ACSA_RHILO - Acetyl-coenzyme A synthetase OS=Rhizobium loti GN=acsA PE=3 SV=1 ACSA_RHILO - Acetyl-coenzyme A synthetase OS=Rhizobium loti (strain MAFF303099) GN=acsA PE=3 SV=1	0.0	[3..534]	[74..621]
ACSA_SALTY - Acetyl-coenzyme A synthetase OS=Salmonella typhimurium GN=acs PE=1 SV=1 ACSA_SALTY - Acetyl-coenzyme A synthetase OS=Salmonella typhimurium GN=acs PE=1 SV=1 lcl\|NC_016856.1_... - [gene=acs] [protein=acetyl-CoA synthetase] [protein_id=YP_005240576.1] [location=complement(4527256.... gi\|197244220, gi... - gi\|197265965\|ref\|ZP_03166039.1\| acetate--CoA ligase [Salmonella enterica subsp. enterica serovar Sai... ACSA_SALTY - Acetyl-coenzyme A synthetase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=acs ... gi\|205330151, gi... - gi\|205330151\|gb\|EDZ16915.1\| acetate--CoA ligase [Salmonella enterica subsp. enterica serovar 4,[5],1...	0.0	[2..539]	[74..625]
gi\|167426184, gi... - gi\|167426184\|ref\|ZP_02317937.1\| acetate--CoA ligase [Yersinia pestis biovar Mediaevalis str. K197300... gi\|167468260 - gi\|167468260\|ref\|ZP_02332964.1\| acetate--CoA ligase [Yersinia pestis FV-1] ACSA_YERPE - Acetyl-coenzyme A synthetase OS=Yersinia pestis GN=acs PE=3 SV=2 gi\|165990673, gi... - gi\|166010583\|ref\|ZP_02231481.1\| acetate--CoA ligase [Yersinia pestis biovar Antiqua str. E1979001], ... gi\|166213894, gi... - gi\|166213894\|ref\|ZP_02239929.1\| acetate--CoA ligase [Yersinia pestis biovar Antiqua str. B42003004],... gi\|167048137, gi... - gi\|167402487\|ref\|ZP_02307942.1\| acetate--CoA ligase [Yersinia pestis biovar Antiqua str. UG05-0454],... gi\|229836504, gi... - gi\|229836504\|ref\|ZP_04456670.1\| acetyl-coenzyme A synthetase [Yersinia pestis Pestoides A], gi\|22970... gi\|167418710, gi... - gi\|167418710\|ref\|ZP_02310463.1\| acetate--CoA ligase [Yersinia pestis biovar Orientalis str. MG05-102... gi\|161511453 - gi\|161511453\|ref\|NP_991800.2\| acetyl-CoA synthetase [Yersinia pestis biovar Microtus str. 91001] gi\|229842194, gi... - gi\|229842194\|ref\|ZP_04462349.1\| acetyl-coenzyme A synthetase [Yersinia pestis biovar Orientalis str.... gi\|162354221, gi... - gi\|162421406\|ref\|YP_001608244.1\| acetyl-CoA synthetase [Yersinia pestis Angola], gi\|162354221\|gb\|ABX... gi\|229696479, gi... - gi\|229840113\|ref\|ZP_04460272.1\| acetyl-coenzyme A synthetase [Yersinia pestis biovar Orientalis str.... ACSA_YERPN - Acetyl-coenzyme A synthetase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=acs PE=3 SV=1 gi\|165921419, gi... - gi\|165926796\|ref\|ZP_02222628.1\| acetate--CoA ligase [Yersinia pestis biovar Orientalis str. F1991016... ACSA_YERPA - Acetyl-coenzyme A synthetase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=acs PE=3 SV=1 gi\|165936473, gi... - gi\|165936473\|ref\|ZP_02225041.1\| acetate--CoA ligase [Yersinia pestis biovar Orientalis str. IP275], ... gi\|218927458, gi... - gi\|218927458\|ref\|YP_002345333.1\| acetyl-CoA synthetase [Yersinia pestis CO92], gi\|16120590\|ref\|NP_40... gi\|150260700, gi... - gi\|150260700\|ref\|ZP_01917428.1\| acetyl-coenzyme A synthetase [Yersinia pestis CA88-4125], gi\|1492901... ACSA_YERPP - Acetyl-coenzyme A synthetase OS=Yersinia pestis (strain Pestoides F) GN=acs PE=3 SV=1	0.0	[2..539]	[74..625]
gi\|17986522, gi\|... - gi\|17986522\|ref\|NP_539156.1\| acetyl-coenzyme A synthetase [Brucella melitensis 16M], gi\|17982126\|gb\|... gi\|25293392 - gi\|25293392\|pir\|\|AI3281 acetate-CoA ligase (EC 6.2.1.1) [imported] - Brucella melitensis (strain 16M...	0.0	[3..536]	[92..643]
ACSA_PASMU - Acetyl-coenzyme A synthetase OS=Pasteurella multocida (strain Pm70) GN=acsA PE=3 SV=1 ACSA_PASMU - Acetyl-coenzyme A synthetase OS=Pasteurella multocida GN=acsA PE=3 SV=1	0.0	[2..537]	[79..631]
ACSA2_PSEAE, ACS... - Acetyl-coenzyme A synthetase 2 OS=Pseudomonas aeruginosa GN=acsA2 PE=3 SV=1, (Q9HV66) Acetyl-coenzym... ACSA2_PSEAE - Acetyl-coenzyme A synthetase 2 OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / ...	0.0	[3..539]	[74..622]
gi\|25293385, gi\|... - gi\|25293385\|pir\|\|AH2913 acetyl-coenzyme A synthetase acs [imported] - Agrobacterium tumefaciens (str... gi\|15889994, gi\|... - gi\|17936620\|ref\|NP_533410.1\| acetyl-coenzyme A synthetase [Agrobacterium tumefaciens str. C58], gi\|1...	0.0	[3..534]	[79..626]

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Predicted Domain #1

Region A:
Residues: [1-19]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSAATVTAS FNDTFSVSD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [33-193]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TYRDLSHMVG HFQTMFTNPN SPLYGAVFRQ DTVAISMRNG LEFIVAFLGA TMDAKIGAPL  60
   61 NPNYKEKEFN FYLNDLKSKA ICVPKGTTKL QSSEILKSAS TFGCFIVELA FDATRFRVEY 120
  121 DIYSPEDNYK RVIYRSLNNA KFVNTNPVKF PGFARSSDVA L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	477.0
Match:	1ba3__
Description:	Luciferase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [20-32]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVAVIVPETD TQV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [194-433]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILHTSGTTST PKTVPLLHLN IVRSTLNIAN TYKLTPLDRS YVVMPLFHVH GLIGVLLSTF  60
   61 RTQGSVVVPD GFHPKLFWDQ FVKYNCNWFS CVPTISMIML NMPKPNPFPH IRFIRSCSSA 120
  121 LAPATFHKLE KEFNAPVLEA YAMTEASHQM TSNNLPPGKR KPGTVGQPQG VTVVILDDND 180
  181 NVLPPGKVGE VSIRGENVTL GYANNPKANK ENFTKRENYF RTGDQGYFDP EGFLVLTGRI 240
  241

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	477.0
Match:	1ba3__
Description:	Luciferase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [434-543]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KELINRGGEK ISPIELDGIM LSHPKIDEAV AFGVPDDMYG QVVQAAIVLK KGEKMTYEEL  60
   61 VNFLKKHLAS FKIPTKVYFV DKLPKTATGK IQRRVIAETF AKSSRNKSKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	477.0
Match:	1ba3__
Description:	Luciferase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits