YRC Public Data Repository - Protein Structure Prediction

Protein:	ATG12
Organism:	Saccharomyces cerevisiae
Length:	186 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG12.

Description	E-value	Query Range	Subject Range
gi\|119569340, gi... - gi\|52632420\|gb\|AAH12266.2\| ATG12 autophagy related 12 homolog (S. cerevisiae) [Homo sapiens], gi\|382...	200.0	[0..55]	[186..54]
ATG12_MOUSE - Ubiquitin-like protein ATG12 OS=Mus musculus GN=Atg12 PE=1 SV=1	200.0	[0..67]	[186..21]
ATG12_PONAB - Ubiquitin-like protein ATG12 OS=Pongo abelii GN=ATG12 PE=2 SV=1 ATG12_PONPY - Autophagy-related protein 12 - Pongo pygmaeus (Orangutan)	196.0	[0..67]	[186..20]
gi\|73970487 - gi\|73970487\|ref\|XP_531866.2\| PREDICTED: similar to Autophagy protein 12-like (APG12-like) (ATG12) is...	192.0	[0..71]	[186..24]
ATG12_RAT - Ubiquitin-like protein ATG12 OS=Rattus norvegicus GN=Atg12 PE=2 SV=1	190.0	[0..56]	[186..10]
ATG12_BOVIN - Ubiquitin-like protein ATG12 OS=Bos taurus GN=ATG12 PE=2 SV=1	188.0	[0..55]	[186..7]
gi\|50762174 - gi\|50762174\|ref\|XP_424963.1\| PREDICTED: hypothetical protein [Gallus gallus]	169.0	[0..67]	[186..22]

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Predicted Domain #1

Region A:
Residues: [1-74]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRILESENE TESDESSIIS TNNGTAMERS RNNQELRSSP HTVQNRLELF SRRLSQLGLA  60
   61 SDISVDQQVE DSSS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [75-186]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTYEQEETIK TNAQTSKQKS HKDEKNIQKI QIKFQPIGSI GQLKPSVCKI SMSQSFAMVI  60
   61 LFLKRRLKMD HVYCYINNSF APSPQQNIGE LWMQFKTNDE LIVSYCASVA FG

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	14.04
Match:
Description:	No description for 1kjtA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits