YRC Public Data Repository - Protein Structure Prediction

Protein:	FTH1
Organism:	Saccharomyces cerevisiae
Length:	465 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FTH1.

Description	E-value	Query Range	Subject Range
FTH1_YEAST - Iron transporter FTH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FTH1 PE=1 SV=2 gi\|151946595 - gi\|151946595\|gb\|EDN64817.1\| fts3-like protein [Saccharomyces cerevisiae YJM789] gi\|207347556 - gi\|207347556\|gb\|EDZ73687.1\| YBR207Wp-like protein [Saccharomyces cerevisiae AWRI1631] FTH1 - Putative high affinity iron transporter involved in transport of intravacuolar stores of iron; forms...	0.0	[1..465]	[1..465]
gi\|238878207 - gi\|238878207\|gb\|EEQ41845.1\| plasma membrane iron permease [Candida albicans WO-1] gi\|7770293 - gi\|7770293\|gb\|AAF69681.1\| high-affinity iron permease CaFTR2 [Candida albicans]	0.0	[114..424]	[32..348]
FIP1_SCHPO - Plasma membrane iron permease OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fip1 PE=1 SV... fip1 - iron permease Fip1	6.0E-98	[115..444]	[38..350]
gi\|18977095, gi\|... - gi\|18977095\|ref\|NP_578452.1\| hypothetical protein PF0723 [Pyrococcus furiosus DSM 3638], gi\|18892738...	3.0E-45	[126..393]	[26..264]
gi\|224502342 - gi\|224502342\|ref\|ZP_03670649.1\| hypothetical protein LmonFR_07454 [Listeria monocytogenes FSL R2-561... gi\|25309253, gi\|... - pir\|\|AF1120 conserved hypothetical protein homolog lmo0365 [imported] - Listeria monocytogenes (stra... gi\|16802410 - gi\|16802410\|ref\|NP_463895.1\| hypothetical protein lmo0365 [Listeria monocytogenes EGD-e]	8.0E-45	[128..321]	[258..435]
gi\|16799461 - gi\|16799461\|ref\|NP_469729.1\| hypothetical protein lin0384 [Listeria innocua Clip11262] gi\|25309255, gi\|... - pir\|\|AI1480 conserved hypothetical protein homolog lin0384 [imported] - Listeria innocua (strain Cli...	1.0E-44	[128..321]	[258..435]
gi\|13360723, gi\|... - gi\|15830517\|ref\|NP_309290.1\| putative cytochrome [Escherichia coli O157:H7 str. Sakai], gi\|13360723\|... gi\|253773953, gi... - gi\|253773953\|ref\|YP_003036784.1\| FTR1 family protein [Escherichia coli BL21(DE3)], gi\|253324997\|gb\|A... gi\|242376828, gi... - gi\|251784555\|ref\|YP_002998859.1\| hypothetical protein B21_01026 [Escherichia coli BL21], gi\|24237682... gi\|189358185, gi... - gi\|189358185\|gb\|EDU76604.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4401]... gi\|188018213, gi... - gi\|188018213\|gb\|EDU56335.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4113]... gi\|254792275, gi... - gi\|254792275\|ref\|YP_003077112.1\| ferrous iron permease [Escherichia coli O157:H7 str. TW14359], gi\|2... gi\|157160541, gi... - gi\|157160541\|ref\|YP_001457859.1\| iron permease FTR1 family protein [Escherichia coli HS], gi\|1570662... gi\|157156355, gi... - gi\|157156355\|ref\|YP_001462251.1\| FTR1 family iron permease [Escherichia coli E24377A], gi\|157078385\|... gi\|189001223, gi... - gi\|189001223\|gb\|EDU70209.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4076]... gi\|187770528, gi... - gi\|187770528\|gb\|EDU34372.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4196]... gi\|189363226, gi... - gi\|189363226\|gb\|EDU81645.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4486]... gi\|189368764, gi... - gi\|189368764\|gb\|EDU87180.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4501]... gi\|208737587, gi... - gi\|208822102\|ref\|ZP_03262421.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4... gi\|208815062, gi... - gi\|208815062\|ref\|ZP_03256241.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4... gi\|208806187, gi... - gi\|208806187\|ref\|ZP_03248524.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4... gi\|195935275 - gi\|195935275\|ref\|ZP_03080657.1\| FTR1 family protein [Escherichia coli O157:H7 str. EC4024] gi\|217318813, gi... - gi\|217328386\|ref\|ZP_03444468.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. TW1... gi\|209911531, gi... - gi\|209918272\|ref\|YP_002292356.1\| putative cytochrome [Escherichia coli SE11], gi\|209911531\|dbj\|BAG76... gi\|209398317, gi... - gi\|209398317\|ref\|YP_002269743.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC... gi\|190903004, gi... - gi\|191166892\|ref\|ZP_03028716.1\| iron permease FTR1 family protein [Escherichia coli B7A], gi\|1909030... gi\|188490646, gi... - gi\|188495447\|ref\|ZP_03002717.1\| iron permease FTR1 family protein [Escherichia coli 53638], gi\|18849... gi\|124500101, gi... - gi\|124529146\|ref\|ZP_01700256.1\| FTR1 family protein [Escherichia coli B], gi\|124500101\|gb\|EAY47579.1... gi\|169755511, gi... - gi\|170020583\|ref\|YP_001725537.1\| FTR1 family protein [Escherichia coli ATCC 8739], gi\|169755511\|gb\|A... gi\|189372680, gi... - gi\|189372680\|gb\|EDU91096.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC869],... gi\|194438030, gi... - gi\|194438030\|ref\|ZP_03070123.1\| iron permease FTR1 family protein [Escherichia coli 101-1], gi\|19442... EFEU_SHISS - Ferrous iron permease EfeU OS=Shigella sonnei (strain Ss046) GN=efeU PE=3 SV=2 gi\|194413547, gi... - gi\|194428495\|ref\|ZP_03061035.1\| iron permease FTR1 family protein [Escherichia coli B171], gi\|194413... gi\|192955913, gi... - gi\|193070802\|ref\|ZP_03051736.1\| iron permease FTR1 family protein [Escherichia coli E110019], gi\|192... gi\|192927854, gi... - gi\|193064602\|ref\|ZP_03045682.1\| iron permease FTR1 family protein [Escherichia coli E22], gi\|1929278... gi\|25390170 - pir\|\|G90786 probable cytochrome [imported] - Escherichia coli (strain O157:H7, substrain RIMD 050995... EFEU_ECO57 - Ferrous iron permease EfeU OS=Escherichia coli O157:H7 GN=efeU PE=1 SV=3	2.0E-44	[126..331]	[26..220]

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Predicted Domain #1

Region A:
Residues: [1-465]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFEDYFSFQ IFFIFLRKSL EIVVIVSILL TIVKQDLSVE DDSPFEGSSS SAGLPSPNTN  60
   61 TNADSTTAFL QAGPSDGNAI GTSATAANNK SRPLNVEEEE EIYEYSNELR DQDRESDEHT 120
  121 ADNVKLYQKL KIQILAGGAF GLLLCMLIGG AFVSIFYHIG TDLWTLSEHY YEGVLSLVAS 180
  181 VIISVMGLFF LRMGKLREKF RVKLASIIYS KDNNLLGNKT QKGVKFSQKY SFFILPFITT 240
  241 LREGLEAVYS IGGIGIDQPL SSIPLSMVLA TAISTVFGIF FFRYSSSLSL KICLVVATCF 300
  301 LYLIAAGLFS KGVWQLELQD YVNKCNGQDM SEVENGPGSY DISRSVWHVN CCNGEKDGGW 360
  361 MIFTAIFGWT NSATVGSVIS YNAYWLVLKY ALKLLMIEGK CGYIPYLPIS WQKKRIMKRL 420
  421 SIAKASLDLK HHTSELNSST SEPDSQRRSK DSSVPLIIDS SGSAN

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	182.481486
Match:	PF03239
Description:	Iron permease FTR1 family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits