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View Structure Prediction Details

Protein: NPL4
Organism: Saccharomyces cerevisiae
Length: 580 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NPL4.

Description E-value Query
Range
Subject
Range
NPL4_YEAST - Nuclear protein localization protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=N...
NPL4 - Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recog...
0.0 [1..580] [1..580]
NPL4_RAT - Nuclear protein localization protein 4 homolog OS=Rattus norvegicus GN=Nploc4 PE=1 SV=3
0.0 [1..580] [5..560]
NPLOC4 - nuclear protein localization 4 homolog (S. cerevisiae)
gi|123997361 - gi|123997361|gb|ABM86282.1| nuclear protein localization 4 homolog (S. cerevisiae) [synthetic constr...
0.0 [1..580] [5..560]
NPL4_SCHPO - Nuclear protein localization protein 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=npl...
npl4 - Cdc48-Ufd1-Npl4 complex component Npl4
0.0 [1..539] [1..532]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [117..580] [87..547]

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Predicted Domain #1
Region A:
Residues: [1-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIRFRSKNG THRVSCQEND LFGTVIEKLV GNLDPNADVD TFTVCEKPGQ GIHAVSELAD  60
   61 RTVMDLGLKH GDMLILNYSD KPANEKDGVN VEIGSVGIDS KGIRQHRYGP LRIKELAVDE 120
  121 ELEKEDGLIP RQKSKLCKHG DRGMCEYCSP LPPWDKEYHE KNKIKHISFH SYLKKLNENA 180
  181 NKKENGSSYI SPLSEPDFRI NKRCHNGH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [209-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPWPRGICSK CQPSAITLQQ QEFRMVDHVE FQKSEIINEF IQAWRYTGMQ RFGYMYGSYS  60
   61 KYDNTPLGIK AVVEAIYEPP QHDEQDGLTM DVEQVKNEML QIDRQAQEMG LSRIGLIFTD 120
  121 LSDAGAGDGS VFCKRHKDSF FLSSLEVIMA ARHQTRHPNV SKYSEQGFFS SKFVTCVISG 180
  181 NLEGEIDISS YQVSTEAEAL VTADMISGST FPSMAYINDT TDERYVPEIF YMKSNEYGIT 240
  241 VKENAKPAFP VDYLLVTLTH GFPNTDTETN SKFVSSTGFP WSNRQAMGQS QDYQELKKYL 300
  301 FNVASSGDFN LLHEKISNFH LLLYINSLQI LSPDEWKLLI ESAVKNEWEE SLLKLVSSAG 360
  361 WQTLVMILQE SG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [185-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGSSYISPLS EPDFRINKRC HNGHEPWPRG ICSKCQPSAI TLQQQEFRMV DHVEFQKSEI  60
   61 INEFIQAWRY TGMQRFGYMY GSYSKYDNTP LGIKAVVEAI YEPPQHDEQD GLTMDVEQVK 120
  121 NEMLQIDRQA QEMGLSRIGL IFTDLSDAGA GDGSVFCKRH KDSFFLSSLE VIMAARHQTR 180
  181 HPNVSKYSEQ GFFSSKFVTC VISGNLEGEI DISSYQVSTE AEALVTADMI SGSTFPSMAY 240
  241 INDTTDERYV PEIFYMKSNE YGITVKENAK PAFPVDYLLV TLTHGFPNTD TETNSK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.24
Match: 2og4A
Description: No description for 2og4A was found.

Predicted Domain #4
Region A:
Residues: [481-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVSSTGFPWS NRQAMGQSQD YQELKKYLFN VASSGDFNLL HEKISNFHLL LYINSLQILS  60
   61 PDEWKLLIES AVKNEWEESL LKLVSSAGWQ TLVMILQESG 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle