| Protein: | IRA1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 3092 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
No multiple sequence alignment data found for IRA1.
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Region A: Residues: [1-401] |
1 11 21 31 41 51
| | | | | |
1 MNQSDPQDKK NFPMEYSLTK HLFFDRLLLV LPIESNLKTY ADVEADSVFN SCRSIILNIA 60
61 ITKDLNPIIE NTLGLIDLIV QDEEITSDNI TDDIAHSILV LLRLLSDVFE YYWDQNNDFK 120
121 KIRNDNYKPG FSSHRPNFHT SRPKHTRINP ALATMLLCKI SKLKFNTRTL KVLQNMSHHL 180
181 SGSATISKSS ILPDSQEFLQ KRNYPAYTEK IDLTIDYIQR FISASNHVEF TKCVKTKVVA 240
241 PLLISHTSTE LGVVNHLDLF GCEYLTDKNL LAYLDILQHL SSYMKRTIFH SLLLYYASKA 300
301 FLFWIMARPK EYVKIYNNLI SSDYNSPSSS SDNGGSNNSD KTSISQLVSL LFDDVYSTFS 360
361 VSSLLTNVNN DHHYHLHHSS SSSKTTNTNS PNSISKTSIK Q
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| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
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Region A: Residues: [402-1193] |
1 11 21 31 41 51
| | | | | |
1 SSVNASGNVS PSQFSTGNDA SPTSPMASLS SPLNTNILGY PLSPITSTLG QANTSTSTTA 60
61 ATTKTDADTP STMNTNNNNN NNNSANLNNI PQRIFSLDDI SSFNSSRKSL NLDDSNSLFL 120
121 WDTSQHSNAS MTNTNMHAGV NNSQSQNDQS SLNYMENIME LYSNYTGSEL SSHTAILRFL 180
181 VVLTLLDSEV YDEMNSNSYR KISEPIMNIN PKDSNTSSWG SASKNPSIRH LTHGLKKLTL 240
241 QQGRKRNVKF LTYLIRNLNG GQFVSDVSLI DSIRSILFLM TMTSSISQID SNIASVIFSK 300
301 RFYNLLGQNL EVGTNWNSAT ANTFISHCVE RNPLTHRRLQ LEFFASGLQL DSDLFLRHLQ 360
361 LEKELNHIDL PKISLYTEGF RVFFHLVSTK KLHEDIAEKT SSVLKRLFCI IADILLKATP 420
421 YFDDNVTKII ASILDGHILD QFDAARTLSN DDHVSFDAAT SVYTEPTEII HNSSDASLVS 480
481 SLSQSPLSIN SGSNITNTRT WDIQSILPTL SNRSSASDLS LSNILTNPLE AQQNNNANLL 540
541 AHRLSGVPTT KRYASPNDSE RSRQSPYSSP PQLQQSDLPS PLSVLSSSAG FSSNHSITAT 600
601 PTILKNIKSP KPNKTKKIAD DKQLKQPSYS RVILSDNDEA RKIMMNIFSI FKRMTNWFIR 660
661 PDANTEFPKT FTDIIKPLFV SILDSNQRLQ VTARAFIEIP LSYIATFEDI DNDLDPRVLN 720
721 DHYLLCTYAV TLFASSLFDL KLENAKREML LDIIVKFQRV RSYLSNLAEK HNLVQAIITT 780
781 ERLTLPLLVG AV
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| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1194-1571] |
1 11 21 31 41 51
| | | | | |
1 GSGIFISLYC SRGNTPRLIK ISCCEFLRSL RFYQKYVGAL DQYSIYNIDF IDAMAQDNFT 60
61 ASGSVALQRR LRNNILTYIK GSDSILLDSM DVIYKKWFYF SCSKSVTQEE LVDFRSLAGI 120
121 LASMSGILSD MQELEKSKSA PDNEGDSLSF ESRNPAYEVH KSLKLELTKK MNFFISKQCQ 180
181 WLNNPNLLTR ENSRDILSIE LHPLSFNLLF NNLGLKIDEL MSIDLSKSHE DSSFVLLEQI 240
241 IIIIRTILKR DDDEKIMLLF STDLLDAVDK LIEIVEKISI KSSKYYKGII QMSKMFRAFE 300
301 HSEKNLGISN HFHLKNKWLK LVIGWFKLSI NKDYDFENLS RPLREMDLQK RDEDFLYIDT 360
361 SIESAKALAY LTHNVPLE
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| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
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Region A: Residues: [1572-1669] |
1 11 21 31 41 51
| | | | | |
1 IPPSSSKEDW NRSSTVSFGN HFTILLKGLE KSADLNQFPV SLRHKISILN ENVIIALTNL 60
61 SNANVNVSLK FTLPMGYSPN KDIRIAFLRV FIDIVTNY
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.829 | c.55.4 | Translational machinery components |
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Region A: Residues: [1670-1727] |
1 11 21 31 41 51
| | | | | |
1 PVNPEKHEMD KMLAIDDFLK YIIKNPILAF FGSLACSPAD VDLYAGGFLN AFDTRNAS
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Region B: Residues: [1944-2017] |
1 11 21 31 41 51
| | | | | |
1 EDPTPISFDY SFLHKFFYLN EFTIRKEIIN ESKLPGEFSF LKNTVMLNDK ILGVLGQPSM 60
61 EIKNEIPPFV VENR
|
| Detection Method: | |
| Confidence: | 280.68867 |
| Match: | 1nf1A |
| Description: | GAP related domain of neurofibromin |
Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [1728-1943] |
1 11 21 31 41 51
| | | | | |
1 HILVTELLKQ EIKRAARSDD ILRRNSCATR ALSLYTRSRG NKYLIKTLRP VLQGIVDNKE 60
61 SFEIDKMKPG SENSEKMLDL FEKYMTRLID AITSSIDDFP IELVDICKTI YNAASVNFPE 120
121 YAYIAVGSFV FLRFIGPALV SPDSENIIIV THAHDRKPFI TLAKVIQSLA NGRENIFKKD 180
181 ILVSKEEFLK TCSDKIFNFL SELCKIPTNN FTVNVR
|
| Detection Method: | |
| Confidence: | 280.68867 |
| Match: | 1nf1A |
| Description: | GAP related domain of neurofibromin |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [2018-2742] |
1 11 21 31 41 51
| | | | | |
1 EKYPSLYEFM SRYAFKKVDM KEEEEDNAPF VHEAMTLDGI QIIVVTFTNC EYNNFVMDSL 60
61 VYKVLQIYAR MWCSKHYVVI DCTTFYGGKA NFQKLTTLFF SLIPEQASSN CMGCYYFNVN 120
121 KSFMDQWASS YTVENPYLVT TIPRCFINSN TDQSLIKSLG LSGRSLEVLK DVRVTLHDIT 180
181 LYDKEKKKFC PVSLKIGNKY FQVLHEIPQL YKVTVSNRTF SIKFNNVYKI SNLISVDVSN 240
241 TTGVSSEFTL SLDNEEKLVF CSPKYLEIVK MFYYAQLKME EDFGTDFSND ISFSTSSSAV 300
301 NASYCNVKEV GEIISHLSLV ILVGLFNEDD LVKNISYNLL VATQEAFNLD FGTRLHKSPE 360
361 TYVPDDTTTF LALIFKAFSE SSTELTPYIW KYMLDGLEND VIPQEHIPTV VCSLSYWVPN 420
421 LYEHVYLAND EEGPEAISRI IYSLIRLTVK EPNFTTAYLQ QIWFLLALDG RLTNVIVEEI 480
481 VSHALDRDSE NRDWMKAVSI LTSFPTTEIA CQVIEKLINM IKSFLPSLAV EASAHSWSEL 540
541 TILSKISVSI FFESPLLSQM YLPEILFAVS LLIDVGPSEI RVSLYELLMN VCHSLTNNES 600
601 LPERNRKNLD IVCATFARQK LNFISGFSQE KGRVLPNFAA SSFSSKFGTL DLFTKNIMLL 660
661 MEYGSISEGA QWEAKYKKYL MDAIFGHRSF FSARAMMILG IMSKSHTSLF LCKELLVETM 720
721 KVFAE
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [2743-3092] |
1 11 21 31 41 51
| | | | | |
1 PVVDDEQMFI IIAHVFTYSK IVEGLDPSSE LMKELFWLAT ICVESPHPLL FEGGLLFMVN 60
61 CLKRLYTVHL QLGFDGKSLA KKLMESRNFA ATLLAKLESY NGCIWNEDNF PHIILGFIAN 120
121 GLSIPVVKGA ALDCLQALFK NTYYERKSNP KSSDYLCYLF LLHLVLSPEQ LSTLLLEVGF 180
181 EDELVPLNNT LKVPLTLINW LSSDSDKSNI VLYQGALLFS CVMSDEPCKF RFALLMRYLL 240
241 KVNPICVFRF YTLTRKEFRR LSTLEQSSEA VAVSFELIGM LVTHSEFNYL EEFNDEMVEL 300
301 LKKRGLSVVK PLDIFDQEHI EKLKGEGEHQ VAIYERKRLA TMILARMSCS
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
