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View Structure Prediction Details

Protein: SHE3
Organism: Saccharomyces cerevisiae
Length: 425 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SHE3.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-57 [1..394] [264..660]
gi|45383668, gi|... - gi|9800486|gb|AAF99314.1|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi|45383668|r...
5.0E-57 [1..394] [1253..1649]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
2.0E-56 [1..392] [1247..1641]
MYH4 - myosin, heavy chain 4, skeletal muscle
2.0E-56 [5..394] [1254..1645]
MYSS_CYPCA - Myosin heavy chain, fast skeletal muscle OS=Cyprinus carpio PE=2 SV=2
3.0E-56 [1..395] [1246..1643]

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Predicted Domain #1
Region A:
Residues: [1-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDQDNTQTS SSKLAPHHNI FMANLESSPT KDRNTSSQNA SSSRVIESLH DQIDMLTKTN  60
   61 LQLTTQSQNL LSKLELAQSK ESKLLENLNL LKNENENLNS IFERKNKKLK ELEKDYSELS 120
  121 NRYNEQKEKM DQLSKLAKNS SAIEQSCSEK LQNMEVNYNS LLESQNLYRD HYSDEISKLN 180
  181 EKIGLLELEL SNQNLNYGSD TSSNSDIELN LNKFNDSVKD LKSLETEKDS KLSKIITHSL 240
  241 DELNLQSWLN LYQTNENLIS TFAEKMDLKD VLKRNDEKIS NKGAVVQTLK KNVQTQVESN 300
  301 NADALSSNNA QDMLPIKMVK LRKTPNTNDS SSNGNSSNNK RRSFYTASPL LSSGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.221849
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [356-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPKSASPVLP GVKRTASVRK PSSSSSKTNV THNNDPSTSP TISVPPGVTR TVSSTHKKKG  60
   61 NSMVVHGAQS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.425 a.4.5 "Winged helix" DNA-binding domain
View Download 0.395 a.4.1 Homeodomain-like
View Download 0.357 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.505 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.505 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.425 a.4.5 "Winged helix" DNA-binding domain
View Download 0.395 a.4.1 Homeodomain-like
View Download 0.357 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.330 d.50.3 PI-Pfui intein middle domain
View Download 0.330 d.50.3 PI-Pfui intein middle domain
View Download 0.317 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.317 d.58.25 Killer toxin KP6 alpha-subunit
View Download 0.308 d.58.3 Protease propeptides/inhibitors
View Download 0.294 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.294 a.60.2 RuvA domain 2-like
View Download 0.289 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.283 d.68.3 SirA-like
View Download 0.260 c.30.1 PreATP-grasp domain
View Download 0.224 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.215 d.58.3 Protease propeptides/inhibitors


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle