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View Structure Prediction Details

Protein: ATG14
Organism: Saccharomyces cerevisiae
Length: 344 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG14.

Description E-value Query
Range
Subject
Range
ATG14 - Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I (with Vps34/15/30p); Atg14p ta...
gi|207347655 - gi|207347655|gb|EDZ73755.1| YBR128Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190408716 - gi|190408716|gb|EDV11981.1| hypothetical protein SCRG_02840 [Saccharomyces cerevisiae RM11-1a]
ATG14_YEAST - Autophagy-related protein 14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG14 PE=1 ...
0.0 [1..344] [1..344]
SMC_METJA - Chromosome partition protein Smc OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JA...
SMC_METJA - Chromosome partition protein smc homolog OS=Methanocaldococcus jannaschii GN=MJ1643 PE=3 SV=2
0.005 [51..156] [241..349]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.005 [51..156] [241..349]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHCPICHHRA HVVYCAHCIN TSPSLLLKLK LDLILLKDEN KELNGKVEQI LNEAMNYDQL  60
   61 DIKRMEKKKD PLMNSLMKLD VLRMKKNNNL IRHRIEQLNE RIYSKRNHIS ELKVEIDNYK 120
  121 CYKVGTGTDK LREQVEISDA KNKLAQVSKI CESARDYKLN LLNNWFVIQK LQDN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 1.84003218039855 bayes_pls_golite062009
protein binding 1.44233807327602 bayes_pls_golite062009
signal transducer activity 0.804943740914237 bayes_pls_golite062009
molecular transducer activity 0.804943740914237 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [175-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQIPFAIAFQ PLISLKNFRI LPLAITNDSI NIMWKYISFF SDILMIKLPY TNKICEQPMF  60
   61 EFSDSIQTVV QRLIKLIINI LQICRHLKLV PSTPMDIPWL LDQYDVDGLF YNMVKRNKMK 120
  121 CRSVSLYWTF GMLYSMVLDN MNNPQRGHPA RRTAPPPTVT GPHDRWYVVG 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle