YRC Public Data Repository - Protein Structure Prediction

Protein:	SEC18
Organism:	Saccharomyces cerevisiae
Length:	758 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC18.

Description	E-value	Query Range	Subject Range
SEC18 - ATPase required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuol... SEC18_YEAST - Vesicular-fusion protein SEC18 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC18 PE=...	0.0	[1..758]	[1..758]
Y1297_ARCFU - Cell division cycle protein 48 homolog AF_1297 OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 ... Y1297_ARCFU, YC9... - (O28972) Cell division cycle protein 48 homolog AF1297, Cell division cycle protein 48 homolog AF_12...	0.0	[22..757]	[19..709]
CDC48_SOYBN - Cell division cycle protein 48 homolog OS=Glycine max GN=CDC48 PE=2 SV=1	0.0	[27..749]	[42..715]
CD48D_ARATH - Cell division control protein 48 homolog D OS=Arabidopsis thaliana GN=CDC48D PE=1 SV=1	0.0	[9..749]	[25..715]
YB56_METJA, Y115... - (Q58556) Cell division cycle protein 48 homolog MJ1156, Cell division cycle protein 48 homolog MJ115... Y1156_METJA - Cell division cycle protein 48 homolog MJ1156 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / ...	0.0	[23..740]	[14..675]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[27..749]	[74..747]
CDC48_CAPAN - Cell division cycle protein 48 homolog OS=Capsicum annuum GN=CAFP PE=2 SV=1	0.0	[9..748]	[25..714]
TERA_RAT - Transitional endoplasmic reticulum ATPase OS=Rattus norvegicus GN=Vcp PE=1 SV=3	0.0	[27..736]	[37..698]

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Predicted Domain #1

Region A:
Residues: [1-103]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKIPGFGKA AANHTPPDMT NMDTRTRHLK VSNCPNNSYA LANVAAVSPN DFPNNIYIII  60
   61 DNLFVFTTRH SNDIPPGTIG FNGNQRTWGG WSLNQDVQAK AFD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1136.522879
Match:	1cr5A_
Description:	N-terminal domain of NSF-N, NSF-Nn; C-terminal domain of NSF-N, NSF-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [104-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFKYSGKQSY LGSIDIDISF RARGKAVSTV FDQDELAKQF VRCYESQIFS PTQYLIMEFQ  60
   61 GHFFDLKIRN VQAIDLGDIE PTSAVATGIE TKGILTKQTQ INFFKGRDGL VNLKS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1136.522879
Match:	1cr5A_
Description:	N-terminal domain of NSF-N, NSF-Nn; C-terminal domain of NSF-N, NSF-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [219-410]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSLRPRSNA VIRPDFKFED LGVGGLDKEF TKIFRRAFAS RIFPPSVIEK LGISHVKGLL  60
   61 LYGPPGTGKT LIARKIGTML NAKEPKIVNG PEILSKYVGS SEENIRNLFK DAEAEYRAKG 120
  121 EESSLHIIIF DELDSVFKQR GSRGDGTGVG DNVVNQLLAK MDGVDQLNNI LVIGMTNRKD 180
  181 LIDSALLRPG RF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.39794
Match:	1hqcA_
Description:	Holliday junction helicase RuvB
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [411-506]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVQVEIHLPD EKGRLQIFDI QTKKMRENNM MSDDVNLAEL AALTKNFSGA EIEGLVKSAS  60
   61 SFAINKTVNI GKGATKLNTK DIAKLKVTRE DFLNAL

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	14.82
Match:	1e32A
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [507-690]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDVTPAFGIS EEDLKTCVEG GMMLYSERVN SILKNGARYV RQVRESDKSR LVSLLIHGPA  60
   61 GSGKTALAAE IALKSGFPFI RLISPNELSG MSESAKIAYI DNTFRDAYKS PLNILVIDSL 120
  121 ETLVDWVPIG PRFSNNILQM LKVALKRKPP QDRRLLIMTT TSAYSVLQQM DILSCFDNEI 180
  181 AVPN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	495.38764
Match:	1nsf__
Description:	Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [691-758]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNLDELNNV MIESNFLDDA GRVKVINELS RSCPNFNVGI KKTLTNIETA RHDEDPVNEL  60
   61 VELMTQSA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	495.38764
Match:	1nsf__
Description:	Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits