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View Structure Prediction Details

Protein: MNN2
Organism: Saccharomyces cerevisiae
Length: 597 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MNN2.

Description E-value Query
Range
Subject
Range
gi|190408814 - gi|190408814|gb|EDV12079.1| golgi alpha-1,2-mannosyltransferase [Saccharomyces cerevisiae RM11-1a]
gi|151946408 - gi|151946408|gb|EDN64630.1| mannosyltransferase [Saccharomyces cerevisiae YJM789]
MNN2_YEAST - Alpha-1,2-mannosyltransferase MNN2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MNN2 ...
MNN2 - Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to for...
0.0 [1..597] [1..597]
gi|1658377 - gi|1658377|gb|AAB18320.1| unknown [Pichia pastoris]
2.0E-88 [80..332] [60..306]

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Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLTKRFSKL FKLTFIVLIL CGLFVITNKY MDENTSVKEY KEYLDRYVQS YSNKYSSSSD  60
   61 AASADDSTPL RDNDEAGNEK LKSFYNNVFN FLMVDSPKGS TAKQYNEACL LKGDIGDRP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [120-313]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DHYKDLYKLS AKELSKCLEL SPDEVASLTK SHKDYVEHIA TLVSPKGTYK GSGIATVGGG  60
   61 KFSLMAFLII KTLRNMGTTL PVEVLIPPGD EGETEFCNKI LPKYNSKCIY VSDILPRETI 120
  121 EKFVFKGYQF KSLALIASSF ENLLLLDADN FPIKPLDNIF NEEPYVSTGL VMWPDFWRRT 180
  181 THPLYYDIAG IAVD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.52
Match: 1ll0A
Description: Glycogenin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyltransferase activity 5.1732667004955 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 4.02812104984198 bayes_pls_golite062009
UDP-glycosyltransferase activity 3.59185576348855 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 3.3757785630345 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 2.9474291454591 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 2.69652752452892 bayes_pls_golite062009
transferase activity 2.3313878748424 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.24840829900507 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.79751747857925 bayes_pls_golite062009
catalytic activity 1.73979371332125 bayes_pls_golite062009
binding 0.75831291352972 bayes_pls_golite062009
nucleotidyltransferase activity 0.641710647713692 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [314-597]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKKRVRNSRD DITPPAVYTK DLKDLSDVPL SDLDGTIPDV STESGQLMIN KTKHLATALL  60
   61 SLFYNVNGPT WYYPIFSQKA AGEGDKETFI AAANFYGLSF YQVRTRTGVE GYHDEDGFHG 120
  121 VAMLQHDFVQ DYGRYLNAME SIGNKYGGTK SADAIKFDKN YSLEKYTEEF FDNEDLNAKN 180
  181 HVDVMFIHSN FPKFDPYDLS KSNFLTTNGK PARSYTALKK VKNYDIELEN FKVLNEYVCV 240
  241 NKNPFKYLDD LLGQDKTEWK RVCGYITDRL AFLESTHDKA IAGK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle