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View Structure Prediction Details

Protein: DSF2
Organism: Saccharomyces cerevisiae
Length: 736 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DSF2.

Description E-value Query
Range
Subject
Range
DSF2 - Deletion suppressor of mpt5 mutation
0.0 [1..736] [1..736]
gi|25496719 - pir||B97033 uncharacterized protein, related to enterotoxins of other Clostridiales [imported] - Clo...
gi|15894364, gi|... - gi|15894364|ref|NP_347713.1| hypothetical protein CAC1079 [Clostridium acetobutylicum ATCC 824], gi|...
1.0E-92 [296..528] [16..235]
gi|1353239 - gi|1353239|gb|AAB01660.1| putative RNA helicase A
9.0E-6 [313..459] [1133..1280]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-4 [290..465] [146..330]
gi|11493967 - gi|11493967|gb|AAG35723.1|AF208033_1 lipase precursor [Staphylococcus warneri]
0.002 [204..523] [3..341]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQNLKNTSW ADRIGSDDQE RKANSSEVSQ SPPPNNSFES SMDSQFSYAH SNKSSISFES  60
   61 IQTTERLLDK LDLSLEDELI LQEALLEEEN ASRNSQLSQT SGPTLCMPAS EFPSLRYRTN 120
  121 PSPTYIQARD RSLIIDNLKE KDSTLRGKYS S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [152-528]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKVERHLPVK SRYSYIVEED YDSETFSGMK PQMNRNEKDY KYPNLENGNR STNRPNPFNF  60
   61 EKYRIENTRL HHLYPTLISD NNTSVDNNAN SKNNRTTSNN INTSTKTDRI SEKQSCPNEF 120
  121 TTTQKSNCLY RNGSSTSTNT SFSEVGQLSK PKTQSSFESE SSSFSKLKLT KSDTTTIKPS 180
  181 PKRSNSSTST ITKTNTMTND ISLPPTPPYK AHKKKTSLNS LKKLFKSPRT RAKNKKDLES 240
  241 EGSSPIRSAT NSLDFSGENI QLPSTSSTIN NSSPHLARYI FPPNPVFHFK TASTPQSSTD 300
  301 KKKNSKARPN RTHLRTFSDF HTTEKDSKIG ELSALTEQSN KPYHPKVRRR TLSLDGMLPN 360
  361 NSTQCMDSFS HKKEGSN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.3
Match: 1i3qA
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [529-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATSKCGKLKF HPEPYDNDES SHIGQAITMR HQGKLEESAQ RLKKACACGN KTAFLLYGLA  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.574 a.4.5 "Winged helix" DNA-binding domain
View Download 0.539 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.434 a.4.5 "Winged helix" DNA-binding domain
View Download 0.422 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.345 a.4.1 Homeodomain-like
View Download 0.304 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.302 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.290 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.284 a.22.1 Histone-fold
View Download 0.281 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.274 a.4.5 "Winged helix" DNA-binding domain
View Download 0.271 a.60.1 SAM/Pointed domain
View Download 0.267 a.28.1 ACP-like
View Download 0.263 d.58.49 YajQ-like
View Download 0.254 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.244 a.4.5 "Winged helix" DNA-binding domain
View Download 0.244 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.221 a.5.6 Hypothetical protein MTH1615
View Download 0.205 a.4.1 Homeodomain-like
View Download 0.202 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin

Predicted Domain #4
Region A:
Residues: [589-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRHGCGVDKN LKLSLGYLMA ATDIKSFAAE VLDLDINPLN FASMDDIPDI APEP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.73
Match: 1klxA
Description: Cysteine rich protein B (HcpB)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [643-736]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAPALYECGM AYLKGLGMDH PDERKGLKFL EKAALLGHVD SMCLSGTIWS KTSNVKKRDL  60
   61 ARAAAWFRIA DKKGANLLGS DWIYKEKYMK QGPK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.73
Match: 1klxA
Description: Cysteine rich protein B (HcpB)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle