YRC Public Data Repository - Protein Structure Prediction

Protein:	BNA4
Organism:	Saccharomyces cerevisiae
Length:	460 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BNA4.

Description	E-value	Query Range	Subject Range
KMO - kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	3.0E-95	[2..460]	[8..449]
KMO_YEAST - Kynurenine 3-monooxygenase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BNA4 PE=1 SV=... BNA4 - Kynurenine 3-mono oxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynure... gi\|207347938 - gi\|207347938\|gb\|EDZ73956.1\| YBL098Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190408916 - gi\|190408916\|gb\|EDV12181.1\| kynurenine 3-mono oxygenase [Saccharomyces cerevisiae RM11-1a]	1.0E-92	[1..460]	[1..460]
KMO_MOUSE - Kynurenine 3-monooxygenase OS=Mus musculus GN=Kmo PE=1 SV=1	2.0E-90	[4..459]	[10..448]
gi\|47522966, gi\|... - gi\|8886493\|gb\|AAF80481.1\|AF163971_1 L-kynurenine 3-monooxygenase Fpk [Sus scrofa], gi\|47522966\|ref\|N...	1.0E-86	[2..452]	[15..448]
KMO_RAT - Kynurenine 3-monooxygenase OS=Rattus norvegicus GN=Kmo PE=1 SV=1	4.0E-84	[4..459]	[10..448]
gi\|15076608, gi\|... - gi\|162952013\|ref\|NP_001106135.1\| kynurenine 3-monooxygenase [Bombyx mori], gi\|15076614\|dbj\|BAB62419....	1.0E-80	[4..453]	[13..453]
gi\|17225371 - gi\|17225371\|gb\|AAL37368.1\|AF325508_1 kynurenine monooxygenase [Aedes aegypti]	3.0E-79	[5..454]	[20..456]
gi\|86515354, gi\|... - gi\|86515354\|ref\|NP_001034500.1\| kynurenine 3-monooxygenase [Tribolium castaneum], gi\|16555103\|gb\|AAL...	4.0E-78	[5..452]	[9..445]
CE06267 - Monooxygenase status:Partially_confirmed UniProt:Q21795 protein_id:CAB00114.1	2.0E-77	[5..448]	[4..448]

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Predicted Domain #1

Region A:
Residues: [1-75]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSESVAIIGA GLVGCLAALA FSKEGYNVTL YDFRQDPRLD TTKNKNLKSI NLAISARGID  60
   61 ALKSIDPDAC EHILQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [109-187]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSVLNNSLLD ELEKSTTELK FGHKLVKIEW TDDKQICHFA IGEDLKTPHT EKYDFVIGCD  60
   61 GAYSATRSQM QRKVEMDFS

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [296-365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CVNCKPYDVP GGKAILLGDA AHAMVPFYGQ GMNCGFEDVR ILMALLKKHS GDRSRAFTEY  60
   61 TQTRHKDLVS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.522879
Match:	1bgn__
Description:	p-Hydroxybenzoate hydroxylase, PHBH; p-Hydroxybenzoate hydroxylase (PHBH)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [76-108]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMIPMKGRMI HDLKGRQESQ LYGLHGEAIN SIN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [188-295]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEYMNLRYIE LYIPPTEEFK PNYGGNFAIA PDHLHIWPRH KFMLIALANS DGSFTSTFFG  60
   61 SKDQISDLIT SKSRVREFLI ENFPDIINIM DLDDAVKRFI TYPKESLV

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [366-460]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITELAKRNYK EMSHDVTSKR FLLRKKLDAL FSIIMKDKWI PLYTMISFRS DISYSRALER  60
   61 AGKQTRILKF LESLTLGMLS IGGYKLFKFL TRERS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.522879
Match:	1bgn__
Description:	p-Hydroxybenzoate hydroxylase, PHBH; p-Hydroxybenzoate hydroxylase (PHBH)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits