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View Structure Prediction Details

Protein: PRS4
Organism: Saccharomyces cerevisiae
Length: 355 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRS4.

Description E-value Query
Range
Subject
Range
gi|9885239 - gi|9885239|emb|CAC04170.1| phosphoribosyl diphosphate synthase isoform 4 [Saccharomyces cerevisiae]
0.0 [1..355] [1..354]
gi|3608149, gi|1... - gi|633140|emb|CAA58717.1| phosphoribosyl diphosphate synthetase; ribose-phosphate pyrophosphokinase ...
0.0 [14..350] [9..351]
KPRS2_SPIOL - Ribose-phosphate pyrophosphokinase 2, chloroplastic OS=Spinacia oleracea GN=PRS2 PE=2 SV=1
0.0 [12..350] [50..394]
CE00745 - Ribose-phosphate pyrophosphokinase status:Confirmed UniProt:Q21994 protein_id:AAK29853.1
0.0 [17..355] [38..376]
PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=3
0.0 [39..355] [1..318]
PRPS1 - phosphoribosyl pyrophosphate synthetase 1
gi|208967042, gi... - gi|208967042|dbj|BAG73535.1| phosphoribosyl pyrophosphate synthetase 1-like 1 [synthetic construct],...
ENSCJAT00000043257 - null
gi|114689771, gi... - gi|114689771|ref|XP_001144504.1| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes], gi|114...
PRPS1_PONAB - Ribose-phosphate pyrophosphokinase 1 OS=Pongo abelii GN=PRPS1 PE=2 SV=1
tr|M3WGN3|M3WGN3... - Phosphoribosyl pyrophosphate synthetase 1 OS=Felis catus GN=PRPS1 PE=3 SV=1
PRPS1_PONPY - Ribose-phosphate pyrophosphokinase I - Pongo pygmaeus (Orangutan)
gi|109131827 - gi|109131827|ref|XP_001095604.1| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phospho...
PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=4
PRPS1_BOVIN - Ribose-phosphate pyrophosphokinase 1 OS=Bos taurus GN=PRPS1 PE=2 SV=3
gi|74008042 - gi|74008042|ref|XP_850853.1| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phosphoribo...
PRPS1_RAT - Ribose-phosphate pyrophosphokinase 1 OS=Rattus norvegicus GN=Prps1 PE=1 SV=2
0.0 [39..355] [1..318]
tr|G3I9Z3|G3I9Z3... - Ribose-phosphate pyrophosphokinase 2 OS=Cricetulus griseus GN=I79_020407 PE=3 SV=1
PRPS2_RAT - Ribose-phosphate pyrophosphokinase 2 OS=Rattus norvegicus GN=Prps2 PE=1 SV=3
0.0 [39..355] [1..318]

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Predicted Domain #1
Region A:
Residues: [1-185]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVIDLEHVVD YIMHIDSQLQ LHKASPAKMN SESREDMAIN SIKLLAGNSH PDLAEQISKK  60
   61 LGIPLSKVGV YQYSNKETSV TIGESLRDED VYIIQTGIGE QEINDFLMEL LILIHACQIA 120
  121 SARKITTVIP NFPYARQDKK DKSRAPITAK LVANLLQTAG ADHVITMDLH ASQIQGFFHI 180
  181 PVDNL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [330-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPTFAEAIRR LHNGESVSYL FTHAPV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 781.54902
Match: 1dkrA_
Description: Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [186-329]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YAEPSVLNYI RARKTDFDNA ILVSPDAGGA KRVAALADKL DLNFALIHKE RQKANEVSKM  60
   61 VLVGDVTNKS CLLVDDMADT CGTLVKACDT LMEHGAKEVI AIVTHGIFSG SAREKLRNSR 120
  121 LSRIVCTNTV PVDLDLPIAD QIDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 781.54902
Match: 1dkrA_
Description: Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle