YRC Public Data Repository - Protein Structure Prediction

Protein:	PRS4
Organism:	Saccharomyces cerevisiae
Length:	355 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRS4.

Description	E-value	Query Range	Subject Range
gi\|9885239 - gi\|9885239\|emb\|CAC04170.1\| phosphoribosyl diphosphate synthase isoform 4 [Saccharomyces cerevisiae]	0.0	[1..355]	[1..354]
gi\|3608149, gi\|1... - gi\|633140\|emb\|CAA58717.1\| phosphoribosyl diphosphate synthetase; ribose-phosphate pyrophosphokinase ...	0.0	[14..350]	[9..351]
KPRS2_SPIOL - Ribose-phosphate pyrophosphokinase 2, chloroplastic OS=Spinacia oleracea GN=PRS2 PE=2 SV=1	0.0	[12..350]	[50..394]
CE00745 - Ribose-phosphate pyrophosphokinase status:Confirmed UniProt:Q21994 protein_id:AAK29853.1	0.0	[17..355]	[38..376]
PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=3	0.0	[39..355]	[1..318]
PRPS1 - phosphoribosyl pyrophosphate synthetase 1 gi\|208967042, gi... - gi\|208967042\|dbj\|BAG73535.1\| phosphoribosyl pyrophosphate synthetase 1-like 1 [synthetic construct],... ENSCJAT00000043257 - null gi\|114689771, gi... - gi\|114689771\|ref\|XP_001144504.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes], gi\|114... PRPS1_PONAB - Ribose-phosphate pyrophosphokinase 1 OS=Pongo abelii GN=PRPS1 PE=2 SV=1 tr\|M3WGN3\|M3WGN3... - Phosphoribosyl pyrophosphate synthetase 1 OS=Felis catus GN=PRPS1 PE=3 SV=1 PRPS1_PONPY - Ribose-phosphate pyrophosphokinase I - Pongo pygmaeus (Orangutan) gi\|109131827 - gi\|109131827\|ref\|XP_001095604.1\| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phospho... PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=4 PRPS1_BOVIN - Ribose-phosphate pyrophosphokinase 1 OS=Bos taurus GN=PRPS1 PE=2 SV=3 gi\|74008042 - gi\|74008042\|ref\|XP_850853.1\| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phosphoribo... PRPS1_RAT - Ribose-phosphate pyrophosphokinase 1 OS=Rattus norvegicus GN=Prps1 PE=1 SV=2	0.0	[39..355]	[1..318]
tr\|G3I9Z3\|G3I9Z3... - Ribose-phosphate pyrophosphokinase 2 OS=Cricetulus griseus GN=I79_020407 PE=3 SV=1 PRPS2_RAT - Ribose-phosphate pyrophosphokinase 2 OS=Rattus norvegicus GN=Prps2 PE=1 SV=3	0.0	[39..355]	[1..318]

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Predicted Domain #1

Region A:
Residues: [1-185]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVIDLEHVVD YIMHIDSQLQ LHKASPAKMN SESREDMAIN SIKLLAGNSH PDLAEQISKK  60
   61 LGIPLSKVGV YQYSNKETSV TIGESLRDED VYIIQTGIGE QEINDFLMEL LILIHACQIA 120
  121 SARKITTVIP NFPYARQDKK DKSRAPITAK LVANLLQTAG ADHVITMDLH ASQIQGFFHI 180
  181 PVDNL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [330-355]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPTFAEAIRR LHNGESVSYL FTHAPV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	781.54902
Match:	1dkrA_
Description:	Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [186-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YAEPSVLNYI RARKTDFDNA ILVSPDAGGA KRVAALADKL DLNFALIHKE RQKANEVSKM  60
   61 VLVGDVTNKS CLLVDDMADT CGTLVKACDT LMEHGAKEVI AIVTHGIFSG SAREKLRNSR 120
  121 LSRIVCTNTV PVDLDLPIAD QIDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	781.54902
Match:	1dkrA_
Description:	Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits