YRC Public Data Repository - Protein Structure Prediction

Protein:	SKT5
Organism:	Saccharomyces cerevisiae
Length:	696 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SKT5.

Description	E-value	Query Range	Subject Range
gi\|415510 - gi\|415510\|gb\|AAC60564.1\| protoplast regeneration and killer toxin resistance gene [Saccharomyces cer...	406.0	[0..15]	[678..1]
gi\|84375186, gi\|... - gi\|84394204\|ref\|ZP_00992934.1\| hypothetical protein V12B01_19651 [Vibrio splendidus 12B01], gi\|84375...	282.0	[0..128]	[691..312]
gi\|69255787, gi\|... - gi\|69255787\|ref\|ZP_00605529.1\| Sel1-like repeat [Magnetococcus sp. MC-1], gi\|68248152\|gb\|EAN30235.1\|...	278.0	[0..86]	[691..215]
gi\|88934891, gi\|... - gi\|88934891\|ref\|ZP_01140530.1\| Sel1-like repeat [Geobacter uraniumreducens Rf4], gi\|88918355\|gb\|EAR3...	254.0	[0..214]	[696..94]
CHR3_SCHPO - Chitin synthase regulatory factor 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=chr3 P... chr3 - chitin synthase regulatory factor Chr3	248.0	[0..37]	[562..394]
gi\|82409304, gi\|... - gi\|82701239\|ref\|YP_410805.1\| Sel1 repeat-containing protein [Nitrosospira multiformis ATCC 25196], g...	244.0	[0..246]	[691..34]
gi\|32477819, gi\|... - gi\|32477819\|ref\|NP_870813.1\| hypothetical protein RB13005 [Rhodopirellula baltica SH 1], gi\|32448376...	238.0	[0..224]	[666..106]
gi\|20073079, gi\|... - gi\|74144524\|dbj\|BAE36100.1\| unnamed protein product [Mus musculus], gi\|46309573\|ref\|NP_035474.1\| Sel...	235.0	[0..101]	[678..19]
gi\|45185913, gi\|... - gi\|45185913\|ref\|NP_983629.1\| ACR227Wp [Ashbya gossypii ATCC 10895], gi\|44981703\|gb\|AAS51453.1\| ACR22... gi\|44981703 - gi\|44981703\|gb\|AAS51453.1\| ACR227Wp [Ashbya gossypii ATCC 10895]	228.0	[0..149]	[542..207]

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Predicted Domain #1

Region A:
Residues: [1-106]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSPQVHPY KKHLMQSQHI NFDNRGLQFQ NSSLKVGQDF SDNKENRENR DNEDFSTADL  60
   61 PKRSANQPLI NEHLRAASVP LLSNDIGNSQ EEDFVPVPPP QLHLNN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.498	a.121.1	Tetracyclin repressor-like, C-terminal domain
View	Download	0.341	a.278.1	Description not found.
View	Download	0.332	d.24.1	Pili subunits
View	Download	0.324	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.319	d.24.1	Pili subunits
View	Download	0.304	a.7.6	Ribosomal protein S20
View	Download	0.303	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.303	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.292	a.181.1	Antibiotic binding domain of TipA-like multidrug resistance regulators
View	Download	0.257	a.29.2	Bromodomain

Predicted Domain #2

Region A:
Residues: [107-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNNTSLSSLG STPTNSPSPG ALRQTNSSTS LTKEQIKKRT RSVDLSHMYL LNGSSDTQLT  60
   61 ATNESVADLS HQMISRYLGG KNNTSLVPRL KTIEMYRQNV KKSKDPEVLF QYAQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.154902
Match:	1fchA
Description:	Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [221-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YMLQTALTIE SSNALVQDSD KEGNVSQSDL KLQFLKEAQS YLKKLSIKGY SDAQYLLADG  60
   61 YSSGAFGKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.154902
Match:	1fchA
Description:	Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [290-379]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENKEAFVLFQ AAAKHGHIES AYRASHCLEE GLGTTRDSRK SVNFLKFAAS RNHPSAMYKL  60
   61 GLYSFYGRMG LPTDVNTKLN GVKWLSRAAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.154902
Match:	1fchA
Description:	Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [380-424]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RANELTAAAP YELAKIYHEG FLDVVIPDEK YAMELYIQAA SLGHV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2.69897
Match:	1a17A
Description:	TETRATRICOPEPTIDE REPEATS OF PROTEIN PHOSPHATASE 5
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [425-552]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSATLLAQIY ETGNDTVGQD TSLSVHYYTQ AALKGDSVAM LGLCAWYLLG AEPAFEKDEN  60
   61 EAFQWALRAA NAGLPKAQFT LGYFYEHGKG CDRNMEYAWK WYEKAAGNED KRAINKLRSR 120
  121 DGGLASIG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2.69897
Match:	1a17A
Description:	TETRATRICOPEPTIDE REPEATS OF PROTEIN PHOSPHATASE 5
Matching Structure (courtesy of the PDB):

Predicted Domain #7

Region A:
Residues: [553-696]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKQHKKNKSI STLNLFSTVD SQTSNVGSNS RVSSKSETFF TGNPKRDREP QGLQINMNSN  60
   61 TNRNGIKTGS DTSIRKSSSS AKGMSREVAE QSMAAKQEVS LSNMGSSNMI RKDFPAVKTE 120
  121 SKKPTSLKNK KDKQGKKKKD CVIM

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.221	a.79.1	Antitermination factor NusB

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits