YRC Public Data Repository - Protein Structure Prediction

Protein:	ECM13
Organism:	Saccharomyces cerevisiae
Length:	257 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECM13.

Description	E-value	Query Range	Subject Range
ECM13 - Non-essential protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irrad... ECM13_YEAST - Protein ECM13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM13 PE=4 SV=1 gi\|190408870 - gi\|190408870\|gb\|EDV12135.1\| extracellular matrix protein 13 [Saccharomyces cerevisiae RM11-1a] gi\|151946350 - gi\|151946350\|gb\|EDN64572.1\| conserved protein [Saccharomyces cerevisiae YJM789]	1.0E-93	[1..257]	[1..257]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-52	[51..201]	[691..839]
gi\|45383822, gi\|... - gi\|45383822\|ref\|NP_989478.1\| matrin 3 [Gallus gallus], gi\|17221616\|dbj\|BAB78469.1\| nuclear protein m...	1.0E-46	[47..200]	[730..895]
gi\|1469809, gi\|6... - gi\|6679098\|ref\|NP_032743.1\| zinc finger protein 638 [Mus musculus], pir\|\|JC4842 DNA-binding nuclear ...	9.0E-45	[48..202]	[1762..1916]
gi\|9956070 - gi\|9956070\|gb\|AAG02007.1\| similar to Homo sapiens mRNA for KIAA0723 protein with GenBank Accession N...	4.0E-44	[51..201]	[251..401]

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Predicted Domain #1

Region A:
Residues: [1-257]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSTTPSIQD QYILASKVRS KLAKCVSVTT KNKDYNLRVL VGHANLLDKI TENVETHNAA  60
   61 TNALAGDPFS KGPENLSIEH IELSNANASK NDVGKEENAE KTIESEDYCD FYSSDEDPDA 120
  121 DTLSSTDSED DDDYEDYDFE YDYSGGDYNK KIDMYFSFHT APNYQYLTHT NSHSEQTDEL 180
  181 AESTPRYNAL PATASTTEEE QDTETLDAVS LHSSAPIFRV LSRRVNGQED DSENESSSDV 240
  241 DDGSVPLTRF HSCPITA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [67-145]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPFSKGPENL SIEHIELSNA NASKNDVGKE ENAEKTIESE DYCDFYSSDE DPDADTLSST  60
   61 DSEDDDDYED YDFEYDYSG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [146-257]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDYNKKIDMY FSFHTAPNYQ YLTHTNSHSE QTDELAESTP RYNALPATAS TTEEEQDTET  60
   61 LDAVSLHSSA PIFRVLSRRV NGQEDDSENE SSSDVDDGSV PLTRFHSCPI TA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.26
Match:	1zr9A
Description:	Solution Structure of a Human C2H2-type Zinc Finger Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.94818133956056	bayes_pls_golite062009
protein binding	0.904295256065987	bayes_pls_golite062009
nucleic acid binding	0.397408203611735	bayes_pls_golite062009
DNA binding	0.173656975405487	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: