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View Structure Prediction Details

Protein: SEN34
Organism: Saccharomyces cerevisiae
Length: 275 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEN34.

Description E-value Query
Range
Subject
Range
gi|151941395 - gi|151941395|gb|EDN59766.1| tRNA splicing endonuclease subunit [Saccharomyces cerevisiae YJM789]
SEN34 - Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; S...
SEN34_YEAST - tRNA-splicing endonuclease subunit SEN34 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
3.0E-88 [1..275] [1..275]
gi|10438595 - gi|10438595|dbj|BAB15284.1| unnamed protein product [Homo sapiens]
2.0E-78 [4..274] [12..309]
SEN34_MOUSE - tRNA-splicing endonuclease subunit Sen34 OS=Mus musculus GN=Tsen34 PE=2 SV=2
3.0E-69 [4..274] [12..315]
SEN34_SCHPO - Probable tRNA-splicing endonuclease subunit sen34 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24...
sen34 - tRNA-splicing endonuclease subunit Sen34
6.0E-67 [4..275] [16..284]
ENDA_SULTO - tRNA-splicing endonuclease OS=Sulfolobus tokodaii GN=endA PE=1 SV=1
ENDA_SULTO - tRNA-splicing endonuclease OS=Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) G...
4.0E-32 [162..273] [69..179]
sen2 - tRNA-splicing endonuclease subunit Sen2
SEN2_SCHPO - Probable tRNA-splicing endonuclease subunit sen2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 248...
3.0E-29 [131..258] [210..333]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPLVFDIDH IKLLRKWGIC GVLSGTLPTA AQQNVFLSVP LRLMLEDVLW LHLNNLADVK  60
   61 LIRQEGDEIM EGITLERGAK LSKIVNDRLN KSFEYQRKFK KDEHIAKLKK IGRINDKTTA 120
  121 EELQRLDKSS NNDQLIESSL FIDIANTSM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [150-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILRDIRSDSD SLSRDDISDL LFKQYRQAGK MQTYFLYKAL RDQGYVLSPG GRFGGKFIAY  60
   61 PGDPLRFHSH LTIQDAIDYH NEPIDLISMI SGARLGTTVK KLWVIGGVAE ETKETHFFSI 120
  121 EWAGFG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.045757
Match: 1a79A_
Description: tRNA splicing endonuclease, C-terminal domain; tRNA splicing endonuclease EdnA, N-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle