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View Structure Prediction Details

Protein: MTW1
Organism: Saccharomyces cerevisiae
Length: 289 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTW1.

Description E-value Query
Range
Subject
Range
MTW1_YEAST - Kinetochore-associated protein MTW1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MTW1...
MTW1 - Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins ...
gi|190406683 - gi|190406683|gb|EDV09950.1| hypothetical protein SCRG_05669 [Saccharomyces cerevisiae RM11-1a]
gi|151941357 - gi|151941357|gb|EDN59728.1| mis12-like protein [Saccharomyces cerevisiae YJM789]
0.0 [1..289] [1..289]
mis12 - kinetochore protein Mis12
MIS12_SCHPO - Centromere protein mis12 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mis12 PE=1 SV=1
4.0E-96 [11..255] [1..252]

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Predicted Domain #1
Region A:
Residues: [1-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAPTMRSTS ILTEHLGYPP ISLVDDIINA VNEIMYKCTA AMEKYLLSKS KIGEEDYGEE  60
   61 IKSGVAKLES LLENSVDKNF DKLELYVLRN VLRIPEEYLD ANVFRLENQK DLVIVDENEL 120
  121 KKSEEKLREK VNDVELAFKK NEMLLKRVTK VKRLLFTIRG FKQKLNELLK CKDDVQLQKI 180
  181 LESLKPIDDT MTLLTDSLRK LYVDSESTSS TEEVEALL

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 1.96
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.43320979925109 bayes_pls_golite062009
protein binding 1.49557135231286 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [219-289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRLKTNGKQN NKDFRTRYID IRTNNVLRKL GLLGDKEDEK QSAKPDARTQ AGDIVSIDIE  60
   61 EPQLDLLDDV L

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 1.96
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle