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View Structure Prediction Details

Protein: MYO4
Organism: Saccharomyces cerevisiae
Length: 1471 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MYO4.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [1..1258] [5..1183]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
 0.0 [3..1292] [32..1270]
gi|4505301, gi|1... - gi|4505301|ref|NP_002463.1| myosin, heavy polypeptide 8, skeletal muscle, perinatal [Homo sapiens], ...
 0.0 [3..1292] [34..1271]
MYH6_MOUSE - Myosin-6 OS=Mus musculus GN=Myh6 PE=1 SV=2
 0.0 [3..1292] [31..1270]
MYO11_ARATH - Myosin-11 OS=Arabidopsis thaliana GN=XI-E PE=3 SV=1
 0.0 [1..1274] [8..1201]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
 0.0 [3..1292] [32..1271]
MYH11_CHICK - Myosin-11 OS=Gallus gallus GN=MYH11 PE=1 SV=4
 0.0 [5..1304] [31..1347]

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Predicted Domain #1
Region A:
Residues: [1-64] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFEVGTKCW YPHKEQGWIG GEVTKNDFFE GTFHLELKLE DGETVSIETN SFENDDDHPT  60
   61 LPVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2640.0
Match: 1jwyA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [65-341] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNPPILESTD DLTTLSYLNE PAVLHAIKKR YMNGQIYTYS GIVLIAANPF DKVDHLYSRE  60
   61 MIQNYSSKRK DELEPHLFAI AEEAYRFMVH EKANQTVVVS GESGAGKTVS AKYIMRYFAS 120
  121 VQESNNREGE VEMSQIESQI LATNPIMEAF GNAKTTRNDN SSRFGKYLQI LFDENTTIRG 180
  181 SKIRTYLLEK SRLVYQPETE RNYHIFYQIL EGLPEPVKQE LHLSSPKDYH YTNQGGQPNI 240
  241 AGIDEAREYK ITTDALSLVG INHETQLGIF KILAGLL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [416-453] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STLFDWLVDN INKTLYDPEL DQQDHVFSFI GILDIYGF

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [649-693] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELMAIINSTN VHYIRCIKPN SEKKPWEFDN LMVLSQLRAC GVLET

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2640.0
Match: 1jwyA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [342-415] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HIGNIEMKMT RNDASLSSEE QNLQIACELL GIDPFNFAKW IVKKQIVTRS EKIVTNLNYN  60
   61 QALIARDSVA KFIY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [454-484] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EHFEKNSFEQ FCINYANEKL QQEFNQHVFK L

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [499-648] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEFSDNQPCI DLIENKLGIL SLLDEESRLP SGSDESWASK LYSAFNKPPS NEVFSKPRFG  60
   61 QTKFIVSHYA VDVEYEVEGF IEKNRDSVSL GHLDVFKATT NPIFKQILDN RELRSDDAPE 120
  121 EQNTEKKIMI PARLSQKKPT LGSMFKKSLG

[Run NCBI BLAST on this sequence.]

Region D:
Residues: [694-697] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2640.0
Match: 1jwyA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [485-498] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQEEYVKEEI EWSF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [698-779] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CAGFPSRWTF DEFVQRYFLL TDYSLWSGIL YNPDLPKEAI VNFCQSILDA TISDSAKYQI  60
   61 GNTKIFFKAG MLAFLEKLRT NK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2640.0
Match: 1jwyA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [780-849] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEICIIIQK KIRARYYRLQ YLQTMESIKK CQSQIRSLLV RTRVDHELKT RAAILLQTNI  60
   61 RALWKREYYR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.0
Match: 1wdcA_
Description: SCALLOP MYOSIN REGULATORY DOMAIN
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [850-914] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAIGQIIKLQ CTCKRKLILD SVNRKFMLMA AVIIQSYIRS YGHKTDYRTL KRSSILVQSA  60
   61 MRMQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [915-996] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARRRYIVLQK EVEERNIRAS YGIGLLEEAI EFKNSFILNL EMLNDSYTRL TQLLQGDLSN  60
   61 IPSKQRQEYE TIVNGYNDKI SK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [997-1056] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKTLQVEIMN TLNKKNALKE RKKKQSSLIQ SHMQSLAAIK GNKPSRLSDE VKSMKQELAF  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #9
Region A:
Residues: [1057-1134] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IENVIAQDFT TTYSANKNDK VKGLGIAGQQ VKPKLVNVIR RESGNPDLLE LLMDLNCYTL  60
   61 EVTEGYLKKV NVTEVNGD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #10
Region A:
Residues: [1135-1231] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVLGPIHVIT TVVSSLVRNG LLIQSSKFIS KVLLTVESIV MSLPKDETML GGIFWLSNLS  60
   61 RLPAFAANQK TLYEANGGDE KDKLTLIYLN DLENETL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [1405-1471] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPNEILNYLA NVIKRENLSL PGKMEIMLSA QFDSAKNHLR YDTSAITQNS NTEGLATVSK  60
   61 IIKLDRK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.17
Match: 1wq1G
Description: p120GAP domain
Matching Structure (courtesy of the PDB):

Predicted Domain #11
Region A:
Residues: [1232-1404] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVFDKIYSTW LVKFMKHASA HIEIFDMVLN EKLFKNSGDE KFAKLFTFLN EFDAVLCKFQ  60
   61 VVDSMHTKIF NDTLKYLNVM LFNDLITKCP ALNWKYGYEV DRNIERLVSW FEPRIEDVRP 120
  121 NLIQIIQAVK ILQLKISNLN EFKLLFDFWY ALNPAQIQAI LLKYKPANKG EAG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.17
Match: 1wq1G
Description: p120GAP domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle