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View Structure Prediction Details

Protein: HIS5_BACFR
Organism: Bacteroides fragilis
Length: 196 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS5_BACFR.

Description E-value Query
Range
Subject
Range
HIS5_BACFN - Imidazole glycerol phosphate synthase subunit HisH OS=Bacteroides fragilis (strain ATCC 25285 / DSM ...
175.0 [0..1] [196..1]

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Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVAVIKYNA GNIRSVDYAL KRLGVEAVIT SDKEVLKAAD KVIFPGVGEA ETTMLHLKES  60
   61 GMDRFIKELR QPVLGICLGM QLMCRFSEEG NVDCLGIFDT DVKRFAPRKH EEKVPHMGWN 120
  121 TISCLKSDLF KGFTRDEFVY FVHSYYVPVS EFTAAETDYI RPFSAALHKD NFYATQFHPE 180
  181 KSGEAGERII KNFLEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.0
Match: 1jvnA
Description: Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF; GAT subunit, HisH, (or domain) of imidazoleglycerolphosphate synthase HisF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
imidazoleglycerol-phosphate synthase activity 8.34101262147614 bayes_pls_golite062009
ligase activity 1.70348758031146 bayes_pls_golite062009
catalytic activity 1.30391542469987 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 0.643287540591989 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.628648036096965 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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