YRC Public Data Repository - Protein Structure Prediction

Protein:	IDE
Organism:	Homo sapiens
Length:	1019 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IDE.

Description	E-value	Query Range	Subject Range
gi\|114631804 - gi\|114631804\|ref\|XP_507922.2\| PREDICTED: insulysin isoform 4 [Pan troglodytes]	0.0	[1..1019]	[1..1019]
gi\|109089936 - gi\|109089936\|ref\|XP_001090249.1\| PREDICTED: insulysin isoform 3 [Macaca mulatta]	0.0	[1..1019]	[1..1019]
IDE_BOVIN - Insulin-degrading enzyme OS=Bos taurus GN=IDE PE=2 SV=1	0.0	[1..1019]	[1..1019]
IDE - insulin-degrading enzyme	0.0	[1..1019]	[1..1019]
gi\|121583922, gi... - gi\|27371196\|gb\|AAH41675.1\| Insulin degrading enzyme [Mus musculus], gi\|121583922\|ref\|NP_112419.2\| in...	0.0	[1..1019]	[1..1019]
IDE_RAT - Insulin-degrading enzyme OS=Rattus norvegicus GN=Ide PE=1 SV=1	0.0	[1..1019]	[1..1019]
gi\|73998234 - gi\|73998234\|ref\|XP_534963.2\| PREDICTED: similar to Insulin-degrading enzyme (Insulysin) (Insulinase)...	0.0	[1..1019]	[1..994]

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Predicted Domain #1

Region A:
Residues: [1-1019]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYRLAWLLH PALPSTFRSV LGARLPPPER LCGFQKKTYS KMNNPAIKRI GNHITKSPED  60
   61 KREYRGLELA NGIKVLLISD PTTDKSSAAL DVHIGSLSDP PNIAGLSHFC EHMLFLGTKK 120
  121 YPKENEYSQF LSEHAGSSNA FTSGEHTNYY FDVSHEHLEG ALDRFAQFFL CPLFDESCKD 180
  181 REVNAVDSEH EKNVMNDAWR LFQLEKATGN PKHPFSKFGT GNKYTLETRP NQEGIDVRQE 240
  241 LLKFHSAYYS SNLMAVCVLG RESLDDLTNL VVKLFSEVEN KNVPLPEFPE HPFQEEHLKQ 300
  301 LYKIVPIKDI RNLYVTFPIP DLQKYYKSNP GHYLGHLIGH EGPGSLLSEL KSKGWVNTLV 360
  361 GGQKEGARGF MFFIINVDLT EEGLLHVEDI ILHMFQYIQK LRAEGPQEWV FQECKDLNAV 420
  421 AFRFKDKERP RGYTSKIAGI LHYYPLEEVL TAEYLLEEFR PDLIEMVLDK LRPENVRVAI 480
  481 VSKSFEGKTD RTEEWYGTQY KQEAIPDEVI KKWQNADLNG KFKLPTKNEF IPTNFEILPL 540
  541 EKEATPYPAL IKDTAMSKLW FKQDDKFFLP KACLNFEFFS PFAYVDPLHC NMAYLYLELL 600
  601 KDSLNEYAYA AELAGLSYDL QNTIYGMYLS VKGYNDKQPI LLKKIIEKMA TFEIDEKRFE 660
  661 IIKEAYMRSL NNFRAEQPHQ HAMYYLRLLM TEVAWTKDEL KEALDDVTLP RLKAFIPQLL 720
  721 SRLHIEALLH GNITKQAALG IMQMVEDTLI EHAHTKPLLP SQLVRYREVQ LPDRGWFVYQ 780
  781 QRNEVHNNCG IEIYYQTDMQ STSENMFLEL FCQIISEPCF NTLRTKEQLG YIVFSGPRRA 840
  841 NGIQGLRFII QSEKPPHYLE SRVEAFLITM EKSIEDMTEE AFQKHIQALA IRRLDKPKKL 900
  901 SAECAKYWGE IISQQYNFDR DNTEVAYLKT LTKEDIIKFY KEMLAVDAPR RHKVSVHVLA 960
  961 REMDSCPVVG EFPCQNDINL SQAPALPQPE VIQNMTEFKR GLPLFPLVKP HINFMAAKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	2g47A
Description:	No description for 2g47A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits