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View Structure Prediction Details

Protein: APTX_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 232 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APTX_SCHPO.

Description E-value Query
Range
Subject
Range
gi|114624091 - gi|114624091|ref|XP_001157540.1| PREDICTED: similar to aprataxin isoform a isoform 4 [Pan troglodyte...
205.0 [0..1] [224..108]
APTX - aprataxin
200.0 [0..1] [224..123]
APTX_PIG - Aprataxin OS=Sus scrofa GN=APTX PE=2 SV=1
199.0 [0..14] [224..161]
APTX_BOVIN - Aprataxin OS=Bos taurus GN=APTX PE=2 SV=1
197.0 [0..1] [224..123]

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Predicted Domain #1
Region A:
Residues: [1-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVHKTNDAF KVLMNSAKEP IVEDIPKKYR KQSFRDNLKV YIESPESYKN VIYYDDDVVL  60
   61 VRDMFPKSKM HLLLMTRDPH LTHVHPLEIM MKHRSLVEKL VSYVQGDLSG LIFDEARNCL 120
  121 SQQLTNEALC NYIKVGFHAG PSMNNLHLHI MTLDHVSPSL KNSAHYISFT SPFFVKIDTP 180
  181 TSNLPTRGTL TSLFQEDLKC WRCGETFGRH FTKLKAHLQE EYDDWLDKSV SM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.39794
Match: 1av5A
Description: Protein kinase C inhibitor-1, PKCI-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.12315862086587 bayes_pls_golite062009
nucleic acid binding 0.724655038971066 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.666122982208826 bayes_pls_golite062009
transferase activity 0.403872263530178 bayes_pls_golite062009
catalytic activity 0.096119422680995 bayes_pls_golite062009
protein binding 0.0635855651106229 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle