YRC Public Data Repository - Protein Structure Prediction

Protein:	CFT2_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	797 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CFT2_SCHPO.

Description	E-value	Query Range	Subject Range
CPSF2 - cleavage and polyadenylation specific factor 2, 100kDa gi\|114654443, gi... - gi\|114654443\|ref\|XP_001147356.1\| PREDICTED: cleavage and polyadenylation specific factor 2 isoform 4...	511.0	[0..1]	[797..4]
CPSF2_MOUSE - Cleavage and polyadenylation specificity factor subunit 2 OS=Mus musculus GN=Cpsf2 PE=1 SV=1	511.0	[0..1]	[797..4]
gi\|109084634 - gi\|109084634\|ref\|XP_001092942.1\| PREDICTED: similar to cleavage and polyadenylation specific factor ...	510.0	[0..1]	[797..4]
gi\|157822735, gi... - ref\|XP_216766.2\| similar to cleavage and polyadenylation specificity factor [Rattus norvegicus], gi\|...	510.0	[0..1]	[797..4]
CPSF2_BOVIN - Cleavage and polyadenylation specificity factor subunit 2 OS=Bos taurus GN=CPSF2 PE=1 SV=1	509.0	[0..1]	[797..4]
gi\|73962293 - gi\|73962293\|ref\|XP_537353.2\| PREDICTED: similar to cleavage and polyadenylation specific factor 2 is...	508.0	[0..1]	[797..4]
gi\|60098929, gi\|... - gi\|71894931\|ref\|NP_001026379.1\| cleavage and polyadenylation specific factor 2 [Gallus gallus], gi\|6...	500.0	[0..1]	[797..4]

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Predicted Domain #1

Region A:
Residues: [1-716]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNYQCLETD SYCGTSHIEL DGIHIYIDPG SDDSLKHPEV PEQPDLILLS HSDLAHIGGL  60
   61 VYAYYKYDWK NAYIYATLPT INMGRMTMLD AIKSNYISDM SKADVDAVFD SIIPLRYQQP 120
  121 TLLLGKCSGL TITAYNAGHT LGGTLWSLIK ESESVLYAVD WNHSKDKHLN GAALYSNGHI 180
  181 LEALNRPNTL ITDANNSLVS IPSRKKRDEA FIESVMSSLL KGGTVLLPVD AASRVLELCC 240
  241 ILDNHWSASQ PPLPFPILFL SPTSTKTIDY AKSMIEWMGD NIVRDFGINE NLLEFRNINT 300
  301 ITDFSQISHI GPGPKVILAT ALTLECGFSQ RILLDLMSEN SNDLILFTQR SRCPQNSLAN 360
  361 QFIRYWERAS KKKRDIPHPV GLYAEQAVKI KTKEPLEGEE LRSYQELEFS KRNKDAEDTA 420
  421 LEFRNRTILD EDLSSSSSSE DDDLDLNTEV PHVALGSSAF LMGKSFDLNL RDPAVQALHT 480
  481 KYKMFPYIEK RRRIDEYGEI IKHQDFSMIN EPANTLELEN DSDDNALSNS NGKRKWSEIN 540
  541 DGLQQKKEEE DEDEVPSKII TDEKTIRVSC QVQFIDIEGL HDGRSLKTII PQVNPRRLVL 600
  601 IHASTEEKED MKKTCASLSA FTKDVYIPNY GEIINVSIDV NAFSLKLADD LIKNLIWTKV 660
  661 GNCEVSHMLA KVEISKPSEE EDKKEEVEKK DGDKERNEEK KEEKETLPVL NALTLR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.0
Match:	2i7xA
Description:	No description for 2i7xA was found.

Predicted functions:

Term	Confidence	Notes
RNA binding	1.48455378212673	bayes_pls_golite062009
nucleic acid binding	0.980281910076056	bayes_pls_golite062009
catalytic activity	0.941400907161877	bayes_pls_golite062009
binding	0.862029507899862	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [717-797]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDLARAPRAA PLLVGNIRLA YLRKALLDQG ISAELKGEGV LLCGGAVAVR KLSGGKISVE  60
   61 GSLSNRFFEI RKLVYDALAV V

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: