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View Structure Prediction Details

Protein: kel-8
Organism: Caenorhabditis elegans
Length: 690 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for kel-8.

Description E-value Query
Range
Subject
Range
gi|157818009, gi... - gi|157818009|ref|NP_001101714.1| kelch-like 4 [Rattus norvegicus], gi|149055486|gb|EDM07070.1| simil...
525.0 [0..15] [664..88]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVYAKAIFG SFPSVQQVRV ENGERCLIEA MDELNKNEKG LYRPVRLENG DQISTTDDVL  60
   61 NGKLARVSYT PFEEFELVSN SK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 2cr2A
Description: Solution structure of N-terminal domain of speckle-type POZ protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [83-223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSCMEYENQE QSSKIMEQMR ILRQTEELCD VELLVAGSVI RAHRYILAAA SPYFKAMFTN  60
   61 GMVEMKKLTI ELQDIPEESV RIIVDYIYTD KIAITMNNVH QLIFTATVLQ MDVIVVACQQ 120
  121 FLATMITSHN CMSLYHFSDI Y

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 2nn2A
Description: No description for 2nn2A was found.

Predicted Domain #3
Region A:
Residues: [224-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NCTNLISSIE DFASSQFRCI RKSPEFNSIS FHHLKSLLNR SDLNVSEEQD VFETIVQWVS  60
   61 SNPRDRQHHF VQLFKTLRLH LVGWNFLCEA VNSNSYVKNS QECREIISAM VLDAMTPSKR 120
  121 KHPESNHEN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.08
Match: 2eqxA
Description: No description for 2eqxA was found.

Predicted Domain #4
Region A:
Residues: [353-690]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSEYSASMAC PSLTASSSSS TSTFRKSVAG AIFCAGGRGK AGGPFSSVEA YDWRRNQWIE  60
   61 VPDMMSQRRH VGVVSANGNL YAIGGHDGTA HLATAEAFQP SIRQWKRIAS MKTARRGIAV 120
  121 ASIENVIYAV GGLDDTTCYK TVERYDIEED EWSTVADMDV QRGGVGVAVI GRYLFAIGGN 180
  181 DGTSSLETCE RFDPMIDKWK RIASMKNRRA GSGVCVLDGY LYAIGGFDDN APLETCERYD 240
  241 PDADKWITLD KMSSPRGGVG VAALGGKVYA IGGHDGSDYL NTVECYDPIA NRWQPAAEIK 300
  301 ECRAGAGVAW ANVRMHQLSR TPEKCDSGCA PSGGSYCI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.69897
Match: 1u6dX
Description: Crystal structure of the Kelch domain of human Keap1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle